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Jaundice capillaris drip pill and its preparation method

A technology of Chen Dropping Pills and Jaundice, which is applied in the field of Jaundice Yinchen Dropping Pills and its preparation, which can solve the problems of low dissolution rate, unfavorable improvement of patients' ability to seek medical treatment, and low drug content, so as to speed up dissolution and absorption and improve bioavailability high degree of bioavailability

Inactive Publication Date: 2007-05-16
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Granules also have defects such as low drug content, inaccurate measurement, and inconvenient taking.
In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0033] Now with several groups of specific examples, the preparation method of the Jaundice Yinchen Dropping Pills of the present invention will be further described.

[0034] Group 1: Tests with a single matrix

[0035] 1. Raw materials: According to the [Appendix], pre-prepared dry powder containing active pharmaceutical ingredients of 4 traditional Chinese medicines, including capillary, scutellaria, rhubarb, and licorice, for future use;

[0036] 2. Substrate: polyethylene glycol (1000～20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0037] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0038] 4. Then prepare according to the process of [Preparation Method] 4-7, and various specifications of Jaundice Yinchen Dropping Pills can be prepared.

[0039] [test results]

[0040] Experim...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating infectious icterohepatitis is prepared from oriental wormwood, scutallaria root, rhubarb, liquorice root and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has heat-clearing and gallbladder-reducing and jaundice-relieving effects, and is used for the treatment of acute and chronic jaundice-type infectious hepatitis, and liver and gallbladder damp-heat syndrome. A pharmaceutical composition oral preparation prepared from extracts of active pharmaceutical ingredients of four traditional Chinese medicines as raw materials. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-10442 (ZD-0442)-2002, Jaundice Yinchen Granules is a kind of jaundice-clearing and gallbladder-reducing effect, which is used for acute and chronic jaundice. Infectious hepatitis, as well as granule preparations for the treatment of diseases such as liver and gallbladder damp-heat syndrome, have been clinically verified for many years, with stable quality and definite curative effect. They are commonly used...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/708A61K36/539A61K36/484A61K36/28A61P1/16A61P31/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司