Preparing method of concentrated Shuanghuanglian oral liquid

A technology of Shuanghuanglian oral liquid and concentrated type is applied in the preparation field of producing concentrated Shuanghuanglian oral liquid, and can solve the problems of oral liquid concentration, low content of active ingredients, incomplete extraction of active ingredients of medicines, inconvenience for taking and carrying, and the like, Achieve the effect of shortening production cycle, increasing cost consumption and shortening production cycle

Active Publication Date: 2004-11-17
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the existing preparation process is realized by traditional extraction and preparation methods, the active ingredient extraction of the medicine is incomplete, the impurity content is high, and the extraction utilization rate is low, resulting in low concentration and active ingredient content of the oral liquid produced. As a result, the oral dosage is increased each time, which is inconvenient to take and carry
In addition, the increase of the dose will also bring a lot of inconvenience to people who have difficulty taking medicine, such as children.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0017] (a) Take 750g of Scutellaria baicalensis slices, add 10 times the amount of water to decoct for 2 hours, filter, add 6 times the amount of water to decoct the medicinal residues twice, each for 1 hour, filter, combine the filtrates three times, concentrate the filtrates and store at 80°C Add appropriate amount of hydrochloric acid solution to adjust the pH value to 2.0, keep it warm for 1 hour, and place it overnight, add 8 times the amount of water to the lower sediment and stir well, adjust the pH value to 7.0 with 40% sodium hydroxide solution, add an equal amount of ethanol, and stir to make Dissolve, filter, adjust the pH value of the filtrate to 2.0 with concentrated hydrochloric acid, place it overnight at 60°C for 30 minutes, filter, wash the precipitate with ethanol until the pH value reaches 7.0, and evaporate the ethanol to obtain the crude extract of Scutellaria baicalensis; Double the amount of water to suspend, adjust the pH value to 7.0, stir until dissolv...

Embodiment 2

[0021] (a) Take 750 g of Scutellaria baicalensis slices, add 9 times the amount of water to decoct for 1 hour and 50 minutes, filter, add 5.5 times the amount of water to decoct the medicinal residues twice, each 50 minutes, filter, combine the filtrate three times, concentrate the filtrate and Add an appropriate amount of hydrochloric acid solution to adjust the pH value to 2.5 at 80°C, keep it warm for 1 hour, and place it overnight, add 7 times the amount of water to the lower sediment and mix well, adjust the pH value to 7.5 with 40% sodium hydroxide solution, and then add an equal amount of ethanol, Stir to dissolve, filter, adjust the pH value of the filtrate to 2.5 with concentrated hydrochloric acid, keep it overnight at 60°C for 30 minutes, filter, wash the precipitate with ethanol until the pH value reaches 7.5, and evaporate the ethanol to obtain the crude extract of Scutellaria baicalensis; Suspend with 5 times the amount of water, adjust the pH value to 7.5, stir u...

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PUM

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Abstract

The invention provides a process for preparing concentration type Shuanghuanglian oral liquid preparation, wherein the preparation comprises flower of honeysuckle, baikal skullcap root and capsule of weeping forsythia. The preparing process comprises acid deposition, alcohol deposition, pH adjustment, extraction, and high speed centrifuging.

Description

(1) Technical field [0001] The invention relates to the field of medicine, in particular to a preparation method for producing concentrated Shuanghuanglian oral liquid. (2) Background technology [0002] Shuanghuanglian Oral Liquid is an antibacterial and antiviral pure Chinese medicine preparation introduced in recent years. It has the effects of dispelling wind and dissipating heat, purging fire and detoxifying, clearing lung and relieving throat, suitable for fever caused by wind-heat, upper respiratory tract infection, tonsillitis, pharyngitis, viral pneumonia, viral enteritis, bacterial enteritis, viral conjunctivitis, Bacterial and viral diseases such as viral keratitis. Due to the significant antibacterial and antiviral effects of Shuanghuanglian, it fills the shortage of clinical antibacterial and antiviral drugs to a certain extent, especially for respiratory infections whose pathogen has not been identified, the use of Shuanghuanglian has also received good curati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/00A61P11/00A61P27/02A61P31/04A61P31/12
Inventor 邢泽田李江华张志平姚静陈进
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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