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Preparation method of achillea effective part medicinal preparation

A technology of effective parts and parts, applied in the field of preparation of effective parts of Artemisia chinensis, can solve problems such as unfavorable recovery of liver disease and liver damage

Inactive Publication Date: 2005-01-05
斯拉甫·艾白 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, many drugs must be oxidized, decomposed, and excreted in the liver, and some can directly cause liver damage, which is not conducive to the recovery of liver disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] a. First, crush the whole herb of Artemisia argyi into powder, extract it with 60% ethanol to obtain an ethanol extract of Artemisia argyi, extract the extract with ethyl acetate, concentrate to obtain the ethyl acetate part, and then dissolve it with dichloromethane , to obtain the dichloromethane site;

[0032] b. Extract the dichloromethane part with 2% sodium bicarbonate to obtain the sodium bicarbonate part, then adjust the pH to 4-5 with hydrochloric acid, extract with dichloromethane, and concentrate to obtain the effective part I mainly composed of ketoacids , its residue is ready for use;

[0033] c. Extract the residue of the dichloromethane part with 2% sodium hydroxide to obtain the sodium hydroxide part, then adjust the pH to 4-5 with hydrochloric acid, extract with dichloromethane, and concentrate to obtain the effective part mainly composed of flavonoids II;

[0034]d. After vacuum-drying the obtained effective fractions I or II or I and II, they can be...

Embodiment 2

[0036] a. First, crush the whole Artemisia argyi into powder, extract it with 95% ethanol to obtain the ethanol extract of Artemisia argyi, and directly dissolve the ethanol extract of Artemisia argyi in dichloromethane to obtain the dichloromethane part;

[0037] b. Extract the dichloromethane part with 20% sodium bicarbonate to obtain the sodium bicarbonate part, then adjust the pH to 4-5 with sulfuric acid, extract with ethyl acetate, and concentrate to obtain the effective part I mainly composed of ketoacids , its residue is ready for use;

[0038] c. Extract the residue of the dichloromethane part with 15% sodium hydroxide to obtain the sodium hydroxide part, then adjust the pH to 4-5 with sulfuric acid, extract with ethyl acetate, and concentrate to obtain the effective part mainly composed of flavonoids II;

[0039] d. After vacuum-drying the obtained effective fractions I or II or I and II, they can be made into oral solid dosage forms and liquid dosage forms accordin...

Embodiment 3

[0041] a. First, crush the whole herb of Artemisia argyi into powder, extract it with 80% ethanol to obtain an ethanol extract of Artemisia argyi, extract the extract with ethyl acetate, concentrate to obtain the ethyl acetate part, and then dissolve it with dichloromethane , to obtain the dichloromethane site;

[0042] b. Extract the dichloromethane part with 12% sodium bicarbonate to obtain the sodium bicarbonate part, then adjust the pH to 4-5 with acetic acid, extract with dichloromethane, and concentrate to obtain the effective part I mainly composed of ketoacids , its residue is ready for use;

[0043] c. Extract the residue of the dichloromethane part with 10% sodium hydroxide to obtain the sodium hydroxide part, then adjust the pH to 4-5 with acetic acid, extract with dichloromethane, and concentrate to obtain the effective part mainly composed of flavonoids II;

[0044] d. After vacuum-drying the obtained effective fractions I or II or I and II, they can be made int...

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PUM

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Abstract

An oral Chinese medicine for treating viral hepatitis and liver injuries is prepared from alpine yallow herb through pulverizing, extracting in alcohol and then in ethyl acetate concentrating, dissolving in dichloromethane, extracting by dicarbonate, regulating pH, extracting, concentrating to obtain active component A, extracting the dregs by sodium hydroxide, regulating pH, extracting, concentrating to obtain active component B, proportional mixing A with B, and vacuum drying.

Description

technical field [0001] The invention relates to a preparation method of an effective part preparation of Artemisia argyi. Background technique [0002] Viral hepatitis and liver injury are diseases that damage human health. Among them, viral hepatitis is a global infectious disease that seriously endangers human health. The prognosis of patients is poor. Most patients become chronic and may develop into liver cirrhosis. Liver damage caused by viral hepatitis is mainly mediated by the body's immune response. When the virus activates the body's immune system, it produces sensitized lymphocytes and specific antibodies, especially virus-specific cytotoxic T cells. They can not only react with the virus in the body to kill, but also cause liver damage due to the viral antigen on the surface of the virus-infected liver cells, leading to degeneration, swelling and necrosis of the liver cells. At present, the efficacy of traditional Chinese and Western medicine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/16A61P31/12
Inventor 斯拉甫·艾白哈木拉提·吾甫尔阿吉艾克拜尔阿不都热依木·玉苏甫古力娜·达吾提
Owner 斯拉甫·艾白
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