Method of supercritical CO2 for extracting effective constituent from whole spores of ganoderma lucidum

A technology of Ganoderma lucidum spores and active ingredients, which is applied to medical preparations containing active ingredients, solid solvent extraction, pharmaceutical formulations, etc., can solve problems such as affecting extraction efficiency, and achieve high extraction efficiency, energy saving, and simple process flow. Effect

Active Publication Date: 2005-01-12
钱律余
View PDF1 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional supercritical CO 2 The extraction method, such as the technology disclosed in Chinese patent ZL99123952.0, is to extract active ingredients from Ganoderma lucidum spores alone. 2 The extraction needs to be broken and pulverized, and the obtained spores of Ganoderma lucidum are often agglomerated, which affects the extraction efficiency. Among the extracted active ingredients, the polysaccharide is only 0.24%, and the triterpenes are 7.69%, which cannot meet the needs and needs to be improved urgently.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method of supercritical CO2 for extracting effective constituent from whole spores of ganoderma lucidum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Put 10 kg of Ganoderma lucidum fruiting body and 20 kg of Ganoderma lucidum spores crushed into 200 meshes into extraction kettle 1, and introduce CO 2 , the control temperature is 32°C, the pressure is 12Mpa, and the time is 4 hours, the CO containing whole Ganoderma lucidum spore extract that flows out from said extraction kettle 1 2 into the separation tank 2, CO 2 Flow out from the separation kettle 2 tops, and 1.6 kilograms of whole Ganoderma lucidum spore extracts in oil and paste state flow out from the vacuum separator 2 bottoms.

[0023] Among them: polysaccharide is 0.36%, and triterpene is 8.07%.

Embodiment 2

[0025] Put 20 kg of Ganoderma lucidum fruiting bodies and 10 kg of Ganoderma lucidum spores into extraction kettle 1 with 400 meshes, and inject CO 2 , the control temperature is 48°C, the pressure is 30Mpa, and the time is 5 hours, the CO containing the whole Ganoderma lucidum spore extract flowing out from said extraction kettle 1 2 Into vacuum separator 2, CO 2 Flow out from the vacuum separator 2 tops, and 1.2 kilograms of whole Ganoderma lucidum spore extracts in oil and paste state flow out from the vacuum separator 2 bottoms.

[0026] Among them: polysaccharide is 2.33%, and triterpene is 12.16%.

Embodiment 3

[0028] Adopt the same method as Example 1, but when extracting, add 3 kilograms of edible ethanol with a weight concentration of 70% as a carrier agent to obtain 2.5 kilograms of whole Ganoderma lucidum spore extract in oil and paste state, wherein: polysaccharide is 1.28% , triterpenes are 11.24%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A process for extracting the active components from ganoderma spore by supercritical CO2 includes mixing the ganoderma spora with its sporophores, adding edible alcohol, introducing supercritical CO2, and extracting. Its advantage is high extracting rate.

Description

technical field [0001] The invention relates to a method for extracting effective components of Ganoderma lucidum, in particular to a method using supercritical CO 2 A method for extracting active ingredients from whole Ganoderma lucidum spores. Background technique [0002] As we all know, Ganoderma lucidum is a fungus that has been hailed as the "Auspicious Grass" by medical scientists of all ages, and it can improve the immune function of the human body. Active ingredients extracted from Ganoderma lucidum, such as Ganoderma lucidum triterpenoids and Ganoderma lucidum polysaccharides, can inhibit the synthesis of lymphocyte DNA and the proliferation of T and B lymphocytes under certain conditions. For this reason, how to extract active ingredients from Ganoderma lucidum, especially from whole Ganoderma lucidum spores, has become a research hotspot. Said whole ganoderma spores refer to ganoderma spores and ganoderma fruiting bodies. Conventional supercritical CO 2 The e...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61P37/04B01D11/02
Inventor 钱律余
Owner 钱律余
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap