Chinese medicine capsule for treating hyperplasia of mammary glands and its producing method

A technology for traditional Chinese medicine capsules and mammary gland hyperplasia, which is applied in the directions of capsule delivery, pharmaceutical formulations, and drug combinations, can solve the problems of limited popularization and application, unable to meet clinical needs, and clinical efficacy needs to be further improved.

Inactive Publication Date: 2005-03-02
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of traditional Chinese medicine for this disease is mainly based on clinical decoction, which limits its popularization and application.
Although there are Chinese patent medicines such as Rupixiao Tablets, Rukuaixiao Tablets, and Rukang Tablets, most of them are local standard drugs that were approved by the provinces before the implementation of the New Drug Application Approval Measures. Either because of the cost or because of its curative effect, or because of its quality or because of the wrong medicine, it is far from meeting the clinical needs, and the clinical curative effect needs to be further improved.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0007] The traditional Chinese medicine capsule of the present invention is formed by putting medicine powder into the capsule, and the medicine powder is composed of 19.48% Cyperus cyperi, 19.48% Danshen, 12.99% Bupleurum 12.99%, 12.99% Baishao, 19.48% Cuilou and Lulu in weight percentage. Pass 15.58% made.

[0008] The production method that realizes is, according to above-mentioned proportioning requirement, add water to be 10 times of drug weight with Cyperus cyperi, Bupleuri, Radix Paeoniae Alba, Trichosanthes chinensis, and Passepartout, soak for 1 hour, decoct for 2 hours, add water 6 times, decoct for 1.5 After decocting for 1 hour, use a volatile oil collector to collect the volatile oil at the same time, set aside, combine the liquid medicine, concentrate it into a thick extract with a relative density of 1.2-2.0, wrap the above volatile oil with β-cyclodextrin, dry it under vacuum at 60°C, and set aside; Add Danshen into ethanol with a mass concentration of 90%, the...

Embodiment 2

[0010] The traditional Chinese medicine capsule of the present invention is made up of capsule and the medicine powder in it, and its medicine powder is made of Cyperus Cyperi 15 grams, Salvia miltiorrhiza 15 grams, Bupleurum bupleurum 10 grams, Radix Paeoniae Alba 10 grams, Trichopina chinensis 15 grams and Passepartout 12 grams. The specific implementation method is to mix 15 grams of Rhizoma Cyperi, 10 grams of Bupleurum, 10 grams of Radix Paeoniae Alba, 15 grams of Trichosanthes and 12 grams of Passepartout, add 620 grams of water (ie 620ml), soak for 1 hour, fry for 1.5 hours, and pour out the medicine. Add 496 grams of water (i.e. 496ml), decoct for 1.5 hours, combine the two medicinal liquids, collect the volatile oil with a volatile oil collector while decocting the medicine, set aside, after the two medicinal liquids are combined, concentrate to a relative density of 1.2-2.0 15 grams of salvia miltiorrhiza miltiorrhiza was added to 90% ethanol and refluxed twice, addin...

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Abstract

The present invention relates to Chinese medicine capsule for treating hyperplasia of mammary glands and its preparation process. The Chinese medicine capsule is prepared with the Chinese medicinal materials including nutagrass flatsedge rhizome, red sage, bupleurum root, white peony root, trichosanthes fruit and sweetgum fruit. The preparation process includes mixing and decocting nutagrass flatsedge rhizome, bupleurum root, white peony root, trichosanthes fruit and sweetgum fruit, concentrating while collecting volatile oil, clathrating with beta-cyclodextrin, alcohol extracting and water extracting red sage, merging the extractum and drying, and capsulizing. The present invention has simple and scientific recipe, rich material, low cost, good clinical effect and other advantages.

Description

1. Technical field [0001] The invention relates to a traditional Chinese medicine capsule for treating mammary gland hyperplasia for treating gynecological breast diseases and a production method thereof. 2. Background technology [0002] Mammary gland hyperplasia is a common and frequently-occurring disease in gynecology. The incidence rate is extremely high in women aged 20-50. Its symptoms are multiple round and tough nodules of different sizes in one or both breasts, often accompanied by breast distending pain, especially before menstruation. Current research shows that the cancerous rate of mammary gland hyperplasia is about 20%, so the research on this disease has attracted much attention in recent years. When the country formulated the "Tenth Five-Year Plan", the research on medication for common (gynecological) diseases has been listed as a key funding scope. Western medicine mostly adopts hormone therapy (proterosterone or methyltestosterone etc.) to the treatment...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61P15/14
Inventor 耿新生苗明三张桂兰王晓红
Owner HENAN UNIV OF CHINESE MEDICINE
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