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Chinese ephedra and almond containing cough stopping dripping pills and its preparing process

A technology of maxing cough and dripping pills, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve problems such as inaccurate dosage, low dissolution rate, and large dust pollution, and improve bioavailability The effect of high degree, fast dissolution and absorption, and no dust pollution

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup preparations also have the disadvantages of low drug content, large doses, inaccurate doses, inconvenient taking, and inconvenient carrying.
[0016] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] The preparation method of Maxing Zhike Dropping Pills of the present invention will be further described with several groups of specific examples.

[0041] Group 1: Tests with a single matrix

[0042] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then follow the section [Appendix: Preparation Method of a Chinese Medicine Extract] to first prepare the ingredients containing ephedra, bitter almond, gypsum, roasted licorice, etc. Extract dry powder of four kinds of pure traditional Chinese medicine active ingredients for standby;

[0043] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0044] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:9;

[0...

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PUM

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Abstract

The invention relates to a medicinal oral preparation with the functions of cough-relieving, phlegm reducing and treating acute, chronic bronchitis, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a pharmaceutical composition with antitussive, expectorant and antiasthmatic effects, which is used for treating acute and chronic bronchitis and wheezing. A kind of pharmaceutical composition oral drop pill preparation of making. Background technique [0002] Maxing cough syrup prepared according to the formula and extraction process given in the national drug standard WS-10757 (ZD-0757)-2002, is a kind of antitussive, expectorant, antiasthmatic effect, used for the treatment of acute, Oral syrup-like pure Chinese medicine preparations for symptoms such as chronic bronchitis and wheezing have been clinically verified to have stable quality and definite curative effect. [0003] The following is the formula and extraction process given in the pharmaceutical standard WS-10757 (ZD-0757)-2002: [0004] Prescription: 120g ephedra, 80g bitter almond, 240g gypsum, 60g licorice (burnt), 625g sucrose, 2g sorbic acid; [0005...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P11/00A61P11/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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