Heat clearing Chinese proprietary capsule(tablet) of 'Ganlu Xiaodu' for treating cold and its preparation process

Abstract

The invention discloses a heat clearing Chinese proprietary capsule (tablet) of 'Ganlu Xiaodu' for treating cold and its preparation process, which comprises eleven kinds of Chinese medicinal herbs including baikal skullcap root, talcum powder, grassleaved sweetflag rhizome and belamcanda rhizome. The preparing process comprises making extract by prescription contents, mixing 100 parts of extract with 2-5 parts of silicon dioxide to prepare capsule, or mixing 100 parts of extract with 0.2-0.5 part of magnesium stearate to obtain tablets, and the content of the active ingredient of baicalin in the extract in no less than 9.0%.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a Chinese patent medicine Ganlu Xiaoxiao Capsule (tablet) for treating colds and clearing away heat and a preparation process thereof. Background technique [0002] In ancient times, Chinese patent medicines for treating colds were mostly pills or powders, but they were inconvenient to take because they were prone to mildew and deterioration in summer, and the dosage was large. In modern times, some ancient prescriptions or classic prescriptions are changed into tablets, capsules or granules. For example, Ganlu Xiaoxiao Pill is an ancient classic prescription, and its dosage form is water pill, (see the Ministry of Health of the People's Republic of China Drug Standards, Volume 9, page 54) mainly used for treating colds and clearing away heat. It has been proved to have significant curative effect through years of clinical practice, and it is safe and safe. ...

AI Technical Summary

Problems solved by technology

For example, Ganlu Xiaoxiao Wan is an ancient classic prescription, and its dosage form is a water pill. (For details, see the Ministry of Health of the People's Republic of China, Volume 9, Page 54 of Drug Standards). Obvious toxic and side effects, but due to the limitations of the dosage form and dosage, the market share has been small, far from meeting the needs of the majority of cold and fever patients

[0003] At present, Ganlu Xiaodu pills mainly have the following problems (1). The long dissolution time generally takes 50 minutes, resulting in slow oral absorption and reduced bioavailability, which is not conducive to the efficacy of the drug; (2). The dosage is relatively large , taking about 86-129 pills each time (equivalent to 6-9 grams of crude drug), causing inconvenience to patients, especially the elderly; It is directly formed into pan pills, so the drug content is low, and there is no quality standard control at present, and it is difficult to meet the hygiene inspection standards, etc.

In short, the solubility, dissolution rate, bioavailability and active ingredient content control of Ganlu disinfection pills need to be further improved.

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