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Granule containing ginseng ,Siberian cocklebur ,lagehead atractylodes and its preparation method

A technology of Shenling Baizhu and granules, applied in the field of preparation of Shenling Baizhu granules, can solve the problems of poor taste, large dosage, unacceptable for children and patients, etc., and achieve the effect of good stability

Active Publication Date: 2006-06-21
BEIJING HANDIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The whole prescription of Shenling Baizhu San is composed of 10 herbs including ginseng, poria cocos, Atractylodes macrocephala, yam, white lentil, lotus seed, coix seed, amomum seed, platycodon grandiflorum and licorice. , eat less loose stools, shortness of breath, cough, limb fatigue, especially for children with weak spleen and stomach, it is a must-have medicine for children, but powder is inconvenient for children to take, and the dosage is large, and the taste is poor, which is difficult for children to accept

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] (1) Extract volatile oil from 200g Amomum seed with steam distillation, and collect the distilled aqueous solution in another device; soak 400g ginseng dregs, 400g Atractylodes rhizome (stir-fried) and add 4-5 times the amount of 95% ethanol for 24 hours, and reflux for 3 hours. hours, filter, ethanol is recovered from the filtrate, and concentrated to a relative density of 1.0 (65°C) to obtain the alcohol extract (a), add 4 to 5 times the amount of 50% ethanol to the dregs, reflux for 3 hours, filter, and the filtrate Recover ethanol, concentrate to a relative density of 1.12-1.13 (80°C) to obtain the alcohol extract (b), and use the dregs for later use;

[0016] (2) Take 200g coix seed (fried), 200g lotus seeds, 300g white lentils (fried), 200g bellflower, 400g licorice, 400g poria cocos, add 8 to 10 times the amount of water and boil for 2 hours, filter, and mix the dregs with the above steps (1 ) after alcohol extraction, add 8 times the amount of water and cook tog...

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PUM

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Abstract

The preparation process of white atractylodes granule with ginseng and tuckahoe includes the following steps: extracting volatile oil of amomum fruit; twice hot alcohol reflux extracting the amomum dreg, ginseng and white atractylodes rhizome, filtering and concentration to obtain alcohol extract and medicine dreg; decocting coix seed, lotus seed, white hyacinth bean, balloonflower root, licorice and tuckahoe, and filtering to obtain filtrate and filter dreg; decocting the medicine dreg and the filter dreg, filtering, merging filtrate and distilled water solution, filtering, concentration, adding the alcohol extract, and concentration to obtain extractum; crushing and sieving Chinese yam and adding the powder into the extractum; crushing the mixture to obtain medicine powder; mixing medicine powder and sugar powder in the weight ratio of 1 to 0.4, adding alcohol solution and pelletizing; and spraying the volatile oil. The present invention has high bioavailability and other advantages.

Description

technical field [0001] The invention relates to a preparation method of Shenling Baizhu Granules. Background technique [0002] The prescription of Shenling Baizhu Granules comes from Shenling Baizhu Powder on page 167 of "Chinese Pharmacopoeia". The whole prescription of Shenling Baizhu San is composed of 10 herbs including ginseng, poria cocos, Atractylodes macrocephala, yam, white lentil, lotus seed, coix seed, amomum seed, platycodon grandiflorum and licorice. , eat less loose stools, shortness of breath, cough, limb fatigue, especially for children with weak spleen and stomach, it is a must-have medicine for children, but powder is inconvenient for children to take, and the dosage is large, and the taste is poor, which is difficult for children to accept. Contents of the invention [0003] The product of the present invention, Shenling Baizhu granule, is formed on the basis of Shenling Baizhu powder through the improvement of dosage form. The purpose of the present ...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K9/16A61P1/14
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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