Medicine composition for preventing and controlling respiratory tract virus and bacterial infection of birds and preparing method

A technology for bacterial infection and respiratory tract, applied in the field of livestock and poultry medicine, can solve problems such as single function, difficult compound ingredients, difficult development and screening, etc., and achieve the effect of convenient use

Active Publication Date: 2006-08-09
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complexity of the mechanism of action of traditional Chinese medicine in animals and the difficulty of quantifying the components of the compound formula, it is still very difficult to develop and screen a very effective drug that can be used on a large scale in clinical practice. , and the function is single

Method used

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  • Medicine composition for preventing and controlling respiratory tract virus and bacterial infection of birds and preparing method
  • Medicine composition for preventing and controlling respiratory tract virus and bacterial infection of birds and preparing method
  • Medicine composition for preventing and controlling respiratory tract virus and bacterial infection of birds and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] ①According to the formula, weigh 400g Radix Isatidis, 200g Rhizoma Coptidis, 250g Honeysuckle, 300g Scutellaria, 200g Shandougen, 150g Licorice, add 4 times distilled water for the first time, heat to boiling, extract for 0.5 hour, filter and take the filtrate; Add 7 times the amount of water at a time, heat to boiling for 1 hour, and collect the filtrate by filtration; the third time is the same as the second time, then the three extracts are combined and heated and concentrated to 1200ml.

[0027] ②Add ethanol to make the ethanol concentration of the drug solution 50%. After shaking, let it stand overnight at low temperature, centrifuge to drive off the precipitate, recover the supernatant, and heat under reduced pressure to recover ethanol to make the drug solution volume to 1200ml. Use the above method to pass 65% and 80% ethanol and alcohol precipitation twice, and finally concentrate the liquid to 1200ml.

[0028] ③ Add 3g of sodium bisulfite to the solution and stir ...

Embodiment 2

[0030] ①According to the formula, weigh 400g Isatis root, 200g Rhizoma Coptidis, 250g Honeysuckle, 300g Scutellaria baicalensis, 200g Shandou root, 150g licorice, add 4 times distilled water for the first time, heat to boiling, extract for 1 hour, filter the filtrate; Add 6 times the amount of water at a time, heat to boiling for extraction for 1 hour, and collect the filtrate by filtration; the third time is the same as the second time, then the three extracts are combined and heated to 1200ml.

[0031] ②Add ethanol to make the ethanol concentration of the drug solution 50%. After shaking, let it stand overnight at a low temperature, centrifuge to remove the precipitate, recover the supernatant, and heat under reduced pressure to recover ethanol to make the drug solution volume to 1200ml. After 65% and 80% ethanol and alcohol precipitation 2 times, the liquid medicine is finally concentrated to 1200ml.

[0032] ③ Add 3g of sodium bisulfite to the liquid medicine and stir to disso...

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Abstract

The present invention discloses a medicine composition for curing avian respirovirus and bacterial infection and its preparation method. Said medicine composition is characterized by that every 1500 ml of liquid medicine contains 350-450 g of isatis root, 150-250 g of coptis root, 225-275 g of lonicera flower, 270-330 g of sculellaria root, 180-220 g of bushy sophora root, 135-165 g of licorice, 225-250 ml of 95% ethyl alcohol, 3 g of sodium bisulfite and the rest is distilled water. Besides, said invention also provides the concrete steps of its preparation method.

Description

Technical field [0001] The invention belongs to livestock and poultry medicines, in particular to a pharmaceutical composition for preventing and treating respiratory virus and bacterial infections of birds and a preparation method thereof. Background technique [0002] Infectious diseases of the respiratory tract of poultry occupies a very important position in the whole poultry diseases, among which viral and bacterial diseases account for more than 80%. At present, the number of poultry species and disease species are increasing, which not only seriously affects the development of the poultry industry, but also the serious threats to human health caused by poultry viruses infecting the human body and human and poultry comorbidities have attracted the attention of the international community. Due to the complex immune program, the potential danger of attenuated vaccines, the weak antigenicity of inactivated vaccines, the reduced protection rate of some vaccines, and the lack of...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61P11/00A61P31/12A61P31/04A61K33/04
Inventor 张继瑜李剑勇周绪正李金善李宏胜蒲小霞魏小娟徐忠赞
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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