Application of physalis alkekengi polysaccharide in preparation of medicine and health care product for treating diabetes

Abstract

An application of the Calyx Seu Fructus Physalis' polyose in preparing the medicine and hypoglycemic health-care food for treating diabetes is disclosed. Its preparing process includes such steps as adding the fruits of Calyx Seu Fructus Physalis in deionized water, heating, filtering, concentrating, stirring, depositing, centrifugal separation and vacuum drying.

Description

technical field

[0001] The invention belongs to the application in the field of pharmacy, and in particular relates to the application of the polysaccharide from the fruit of the lantern in the preparation of medicines for treating diabetes and health care products for lowering blood sugar. Background technique

[0002] With social progress and rapid economic development, the incidence of diabetes is increasing day by day, and young and middle-aged people join the "army" of diabetes at twice the rate of the elderly. Therefore, drugs related to the prevention and treatment of diabetes have become the focus and development trend of international and domestic research.

[0003] At present, the hypoglycemic market in my country is dominated by western medicine, accounting for about 73.68% of the entire market share; supplemented by Chinese patent medicine, accounting for about 24.7%. Chemical prescription drugs account for the absolute dominant share of hypoglycemic products. A...

Examples

Embodiment Construction

[0013] Step 1: Add 1Kg of fresh or dried Carambola japonica, add 5-10 times (V / V) deionized water and heat to boil for 2-3 hours, filter the residue; then extract with 5-10 times (V / V) deionized water Combine the filtrate twice; concentrate the filtrate to about 1 / 15 of the original volume, add 4-5 times of ethanol to stir and precipitate, and the precipitate is centrifuged and vacuum-dried to obtain 32 g of crude product of total polysaccharide.

[0014] Step 2: Dissolve the crude polysaccharide in deionized water, centrifuge after repeated freezing and thawing, and discard the precipitate; prepare the polysaccharide in the supernatant to a 2% aqueous solution, add ethanol to make the final concentration 30%, adjust the pH to 2.5, and stand still Overnight, discard the precipitate after centrifugation; continue to add ethanol solution to the supernatant to make the final concentration 70%, let it stand overnight, the precipitate is centrifuged, and vacuum-dried, the obtained c...

technical field

[0001] The invention belongs to the application in the field of pharmacy, and in particular relates to the application of the polysaccharide from the fruit of the lantern in the preparation of medicines for treating diabetes and health care products for lowering blood sugar. Background technique

[0002] With social progress and rapid economic development, the incidence of diabetes is increasing day by day, and young and middle-aged people join the "army" of diabetes at twice the rate of the elderly. Therefore, drugs related to the prevention and treatment of diabetes have become the focus and development trend of international and domestic research.

[0003] At present, the hypoglycemic market in my country is dominated by western medicine, accounting for about 73.68% of the entire market share; supplemented by Chinese patent medicine, accounting for about 24.7%. Chemical prescription drugs account for the absolute dominant share of hypoglycemic products. A...

Examples

Embodiment Construction

[0013] Step 1: Add 1Kg of fresh or dried Carambola japonica, add 5-10 times (V / V) deionized water and heat to boil for 2-3 hours, filter the residue; then extract with 5-10 times (V / V) deionized water Combine the filtrate twice; concentrate the filtrate to about 1 / 15 of the original volume, add 4-5 times of ethanol to stir and precipitate, and the precipitate is centrifuged and vacuum-dried to obtain 32 g of crude product of total polysaccharide.

[0014] Step 2: Dissolve the crude polysaccharide in deionized water, centrifuge after repeated freezing and thawing, and discard the precipitate; prepare the polysaccharide in the supernatant to a 2% aqueous solution, add ethanol to make the final concentration 30%, adjust the pH to 2.5, and stand still Overnight, discard the precipitate after centrifugation; continue to add ethanol solution to the supernatant to make the final concentration 70%, let it stand overnight, the precipitate is centrifuged, and vacuum-dried, the obtained c...