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Traditional Chinese medicine composition for preventing and/or adjuvant therapy of malignant tumor

A malignant tumor and composition technology, which is applied in the fields of food and medicine, can solve problems such as epistaxis, chest tightness, and dreaminess, and achieve the effect of expanding the applicable population

Inactive Publication Date: 2010-10-06
杨德华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in actual use, often produce following side effect: " phenomenons such as dry throat, pharyngalgia, dizziness, tinnitus, epistaxis and uncomfortable in chest, dreaminess ", " Chinese Medicine Encyclopedia " (People's Medical Publishing House, the 3rd Edition 2005, page 516) and "Newly Edited National Chinese Patent Medicine" (People's Medical Publishing House, 2002 edition, page 723) relevant regulations: "People with fiery symptoms or yin deficiency and internal heat should not use it", press, ginseng tastes slightly bitter, Lukewarm

Method used

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  • Traditional Chinese medicine composition for preventing and/or adjuvant therapy of malignant tumor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 Animal experiment

[0021] 1) Test drug raw materials:

[0022] Ginseng extract, in which Rg3 content is 80%, was purchased from Jilin Province Jiuhong Biotechnology Co., Ltd., batch number: 060201;

[0023] Tea extract, in which the content of theaflavins is 23%, and the content of EGCE is 8%, purchased from Wuxi Century Biopharmaceutical Co., Ltd., batch number: S0512001W-3;

[0024] Ganoderma lucidum broken spore powder, with a breaking rate of more than 96%, was purchased from Zhejiang Yisheng Fungus Development Co., Ltd., batch number: 060412.

[0025] 2) Test drug preparation:

[0026] Unilateral ginseng extract: take 2 g of ginseng extract (containing ginsenoside Rg380%), 248 g of lactose, mix well, and prepare a 60 mg / ml suspension with 0.5% tragacanth gum;

[0027] The composition of the present invention: get 2 g of ginseng extract (containing ginsenoside Rg3 80%), 75 g of tea extract and 173 g of Ganoderma lucidum broken spore powder, mix them ev...

Embodiment 2

[0043] Example 2 Preparation of compound ginseng extract powder

[0044] Take ginseng extract 1%, tea extract 20%, Ganoderma lucidum broken spore powder 79% according to the following weight ratio, wherein ginseng extract contains ginsenoside Rg3 90%, tea extract contains EGCG 40%, Ganoderma lucidum broken spore powder The wall-breaking rate is over 96%. The above-mentioned raw materials are mixed evenly, and the powder is prepared by a traditional Chinese medicine powder preparation method.

Embodiment 3

[0045] Example 3 Preparation of compound ginseng extract granules

[0046] Take ginseng extract 2%, tea extract 40%, Ganoderma lucidum broken spore powder 58% according to the following weight ratio; wherein ginseng extract contains 380% ginsenoside Rg, tea extract contains 20% theaflavins and EGCG 6%, The wall breaking rate of the ganoderma lucidum broken spore powder is 96%; the above raw materials are mixed evenly, and the granules are made into granules by the conventional traditional Chinese medicine granule preparation method.

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Abstract

A Chinese medicine in the form of orally taken solid for prevention and / or auxiliary therapy of cancer is prepared from the ginseng extract including ginsenoside Rg3, tea extract and ganoderma.

Description

technical field [0001] The invention belongs to the field of food and medicine, and relates to a traditional Chinese medicine composition for preventing and / or adjuvantly treating malignant tumors. Background technique [0002] In recent years, ginseng extract marked by ginsenoside Rg3 (hereinafter referred to as ginseng extract) has been used in adjuvant cancer treatment, among which there is a product on the market, and its trade name is "Shenyi Capsule". Pharmacological tests show that the above-mentioned ginseng extract can inhibit the protein synthesis of tumor cells in the early stage of mitosis, inhibit the formation of blood vessels around tumor cells, inhibit the adhesion and invasion of tumor cells with fibronectin and laminin, and lead to tumor cell apoptosis. It is used as an adjuvant treatment for postoperative and radiotherapy and chemotherapy of various malignant tumors in clinical practice, to prevent recurrence and metastasis, increase efficiency and reduce ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K9/48A61P35/00A61K9/14A61K9/20A61K36/82
Inventor 杨德华
Owner 杨德华
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