Method for preparing minipill of 'Xue Fu Zhu Yu'

A technology of Xuefu Zhuyu pellets, which is applied in the field of preparation of Xuefu Zhuyu pellets, can solve problems such as moisture-prone, moldy deterioration, unsatisfactory drug stability, and moisture-prone

Inactive Publication Date: 2007-05-30
珠海天翼医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, Xuefu Zhuyu Pills (Ministry of Health Drug Standards Traditional Chinese Medicine Prescription Volume 1), Xuefu Zhuyu Capsules (Ministry of Health Drug Standards Traditional Chinese Medicine Prescription Volume 5), and Xuefu Zhuyu Oral Liquid have been approved for production. (Ministry of Health's new drug standard 13 volumes), Xuefu Zhuyu Pills are made of crushed medicinal materials and then added with condensed milk to make large honeyed pills. It is a traditional dosage form, fully embodying the characteristics of "black, big, and thick", and is prone to mold and deterioration due to moisture; Xuefu Zhuyu Capsules have improved on the basis of pills, but still have the problem of being susceptible to moisture, and the dosage is large, 4 to 6 capsules each time; suboptimal agent

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0014] Prescription: peach kernel 132g, angelica 132g, citrus aurantium 88g, chuanxiong 66g, bupleurum 44g

[0015] Safflower 132g Achyranthes bidentata 132g Radix Paeoniae Rubra 88g Rehmannia glutinosa 132g Bellflower 66g

[0016] Licorice 44g

[0017] Preparation method: Take the above eleven flavors, take peach kernel (1 / 2 of the prescription amount), angelica, red peony root, Ji Ke, Chuanxiong, and Bupleurum, and grind them into fine powder, sieve, mix well, and the remaining 5 medicinal materials such as safflower and Peach kernels (1 / 2 of the prescription amount) are decocted with water for 2 to 4 times, filtered, and the filtrate is combined, and the filtrate is concentrated into a thick paste with a relative density of 1.15~ / Concentrated and dried to make a dry paste powder, add fine powder and pharmaceutically approved The excipients are mixed according to the ratio of 1:0.5~3, pelletized, dried and coated to obtain. Make pellets and dry them; put the d...

Embodiment 2

[0019] Prescription: peach kernel 132g, angelica 132g, citrus aurantium 88g, chuanxiong 66g, bupleurum 44g

[0020] Safflower 132g Achyranthes bidentata 132g Radix Paeoniae Rubra 88g Rehmannia glutinosa 132g Bellflower 66g

[0021] Licorice 44g

[0022] Preparation method: Take the above eleven flavors, take peach kernel (1 / 2 of the prescription amount), angelica, red peony root, Jike, Chuanxiong, and Bupleurum, and grind them into fine powder, sieve, mix well, and the remaining 5 medicinal materials such as safflower and Peach kernels (1 / 2 of the prescription amount) are decocted with water for 2 to 4 times, filtered, and the filtrate is combined, and the filtrate is concentrated into a thick paste with a relative density of 1.15~ / Concentrated and dried to make a dry paste powder, add fine powder and pharmaceutically approved The excipients are mixed according to the ratio of 1:0.5~3, pelletized, dried and coated to obtain. Make pellets and dry them; put the dr...

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Abstract

The invention discloses a process for preparing blood-nourishing micro-pellets by making dressed micro-pellets through conventional pharmaceutical techniques. The invention achieves simple process for manufacturing, stabilized and controllable quality, small amount of administration, shorter disintegration time, and quicker action.

Description

technical field [0001] The invention relates to a preparation method of Xuefu Zhuyu pellets, belonging to the technical field of traditional Chinese medicine. technical background: [0002] Xuefu Zhuyu Decoction comes from the book "Yilin Gaicuo" written by Wang Qingren, a famous doctor in the Qing Dynasty. This prescription is specially developed by Mr. Wang Qingren after summarizing decades of clinical experience for the treatment of "blood stasis". . It is composed of eleven traditional Chinese medicines such as peach kernel, angelica, Jike, Chuanxiong, Bupleurum, safflower, Achyranthes bidentata, red peony root, rehmannia glutinosa, platycodon grandiflorum, and licorice. It is used for internal obstruction of blood stasis, chest pain or headache, cardiovascular and cerebrovascular diseases, menopausal syndrome, treatment of biliary tract infection, insomnia, diabetes and other diseases caused by internal obstruction of blood stasis. In this prescription, peach kernel a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/16A61P9/00A61P15/12A61P1/16A61P25/20A61P3/10
Inventor 张晓明杨岗麦耀权李俊尧
Owner 珠海天翼医药技术开发有限公司
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