Microfluidic Device with a Filter
a microfluidic device and filter technology, applied in the field of chemical or biochemical analysis devices, can solve the problems of clogging flow channels, limiting the packing density that can be achieved and the amount,
Inactive Publication Date: 2008-11-13
CAPLIPER LIFE SCI INC
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- Claims
- Application Information
AI Technical Summary
Benefits of technology
"The invention is a microfluidic device that can filter loose process material from process fluid. The device includes a substrate with a flowpath and a filter across the flowpath. The filter has openings that strain the loose material from the fluid. The method involves depositing the loose material in the flowpath, mixing it with the fluid, and then draining the fluid through the filter. This device can be used to treat process fluids with loose materials."
Problems solved by technology
Microfluidic devices designed to carry out complex analyses will often have complicated networks of intersecting channels with some of the channels being open to the outside of the microfluidic devices through one or more wells.
This limits the packing density that can be achieved and the amount of reaction that can take place in a given volume of the chip.
In addition, beads entering the channels can enter the process in undesirable places and can clog flow channels.
Method used
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[0018]As noted previously, embodiments of the present invention are directed to a microfluidic device with a filter. Microfluidic devices as defined herein are devices with channels having at least one interior dimension, such as depth or radius, of less than one millimeter.
[0019]FIG. 1 is a perspective view of a typical microfluidic device. The top portion of FIG. 1 shows an exploded view of the microfluidic device 100, which includes a well plate 102 and a channel plate 110; and the bottom portion of FIG. 1 shows a side view of the assembled microfluidic device 100 after the well plate 102 and channel plate 110 have been bonded together. Structures such as channels and / or chambers are formed within the interior of the assembled microfluidic device 100 by fabricating a pattern of channels 114, such as grooves and / or trenches, on a surface 112 of the channel plate 110 and bonding a corresponding surface 104 of the well plate 102 onto the patterned surface 112. When the plates are bo...
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Abstract
A microfluidic device with a filter includes a substrate; a flowpath including a well formed in the substrate in fluid communication with a channel formed in the substrate; and a filter disposed across the flowpath.
Description
TECHNICAL FIELD[0001]The present invention relates to chemical or biochemical analysis devices, particularly, a microfluidic device with a filter.BACKGROUND OF THE INVENTION[0002]Microfluidics refers to a set of technologies involving the flow of fluids through channels having at least one linear interior dimension, such as depth or radius, of less than 1 mm. It is possible to create microscopic equivalents of bench-top laboratory equipment such as beakers, pipettes, incubators, electrophoresis chambers, and analytical instruments within the channels of a microfluidic device. Since it is also possible to combine the functions of several pieces of equipment on a single microfluidic device, a single microfluidic device can perform a complete analysis that would ordinarily require the use of several pieces of laboratory equipment. A microfluidic device designed to carry out a complete chemical or biochemical analysis is commonly referred to as a micro-Total Analysis System (μ-TAS) or a...
Claims
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IPC IPC(8): B01D37/00B01L11/00B01L99/00
CPCB01L3/502715B01L3/502761B01L2300/0819B01L2300/0681B01L2300/0816B01L2200/027
Inventor MOURADIAN, STEPHANEMOLHO, JOSHWU, MINGWU, HAYLEYFARINAS, JAVIER A.
Owner CAPLIPER LIFE SCI INC