Method For Manufacturing Molded Article With Core

a manufacturing method and core technology, applied in manufacturing tools, pharmaceutical product form changes, roofs, etc., can solve the problems of restrained core shape and mold disorder, and achieve the effects of preventing the increase in molding size, superb moldability, and preventing the increase in siz

Inactive Publication Date: 2011-01-20
SANWAKAGUKU KENKYUSHO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a method and apparatus for manufacturing a molding with core using a double punch. This method and apparatus allow for the efficient and effective manufacturing of moldings with cores that have high moldability and wear resistance without increasing the size of the finished product. The method and apparatus also allow for the manufacturing of moldings with plural cores and the formation of a thin outer layer. The technical effects of this invention include improved productivity, reduced expense, and the ability to mold cores with plural cores.

Problems solved by technology

As described above, the prior art for the manufacture of a molding with core still holds some problems such as productivity problems, expense problems, occasional manufacturing of a molding without core or with plural cores, problems with centering of the core in the process of supplying of the core and with offset of the core due to the centrifugal force of the rotary table, which furthermore cause molding disorders, restrained shape of a core, etc.

Method used

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  • Method For Manufacturing Molded Article With Core
  • Method For Manufacturing Molded Article With Core
  • Method For Manufacturing Molded Article With Core

Examples

Experimental program
Comparison scheme
Effect test

experimental example 1

Manufacture Example 1

[0169]On the surface of the punches of a double structure with inside diameter of 8.5 mm and outside diameter of 10.0 mm and with pressurizable flat edge, a small amount of magnesium stearate (manufactured by Taihei Kagaku Sangyo) was applied and as the lower central punch was kept in lowered position, in the space above the lower central punch, enclosed by the lower outer punch, 15 mg crystalline cellulose (manufactured by Asahi Kasei: Avicel PH-101) was supplied; then the upper central punch and the lower central punch were moved towards each other and compression was applied manually so as the surface to become flat. Next, as the lower central punch was kept in lowered position, in the space above the temporary moldings of crystalline cellulose, enclosed by the lower outer layer, 300 mg of ascorbic acid (manufactured by Merck Japan: L-ascorbic acid crystal) were supplied; then the upper central punch and the lower central punch were moved towards each other a...

experimental example 2

[0174]The results of experimental example 1 showed that the tablets of manufacture example 1 possess superb degree of friability. The combination proportion of ascorbic acid and crystalline cellulose, which would allow the same degree of friability as in manufacture example 1 while weight of the tablet is unchanged, in the traditional methods for manufacturing of ordinary tablets (same as comparative manufacture example 2) was evaluated.

experimental example 3

[0181]The results of manufacture example show that the tablets of comparative manufacture example 1 have poor moldability and high degree of friability. For this reason evaluation of the pros and cons of manufacturing of compression-coated tablets with poor moldability by the traditional manufacturing methods was performed (comparative manufacture example 6). The core supplying mechanism of the compression-coated tablets making mechanism (manufactured by Hata Tekkojo: HT-AP33-C) cannot be applied for formatting the tablets in the comparative manufacture example 1 (there are problems with supplying the core pills in the die), so the shape of the tablets was changed to 6.5 mm in diameter ordinary R and ascorbic acid was used, which is same as comparative manufacture example 6.

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Abstract

A method for manufacturing molded articles with cores uses a compression molding apparatus that includes upper and lower punches that have a double structure comprising a central punch and an outer punch that surrounds the periphery of the central punch. The central punch and the outer punch are movable and capable either of moving together or sliding with respect to one another. Molding materials are supplied for a core and an outer layer. The molding materials are compressed by the punches to form molded articles that include the core. The method may be executed in a rotary compression molding machine.

Description

RELATED APPLICATIONS[0001]This application is a continuation of U.S. application Ser. No. 10 / 317,360, having a filing date of Dec. 12, 2002, now pending, which is a continuation of International Application PCT / JP2001 / 05296, having an international filing date of Jun. 20, 2001, now abandoned, which claims priority to Japan Application Nos. 2000-183996, filed Jun. 20, 2000, 2000-387052, filed Dec. 20, 2000, 2001-42787, filed Feb. 20, 2001, 2001-74413, filed Mar. 15, 2001, 2001-98571, filed Mar. 30, 2001, and 2001-125690, filed Apr. 24, 2001. Further, International Application PCT / JP2001 / 05296, was filed in the national stage of Japan as Japan Application No. 2002-503525, which issued as Japan Patent No. 4316871 on May 29, 2009. All of which are hereby incorporated herein by reference.TECHNICAL FIELD[0002]The present invention relates generally to a manufacturing method for manufacturing a molding by compressing molding material such as powder granule, an apparatus for use in the meth...

Claims

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Application Information

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Patent Type & AuthorityApplications(United States)
IPC IPC(8): B29C43/20A61J3/06A61J3/10A61K9/20B30B11/00B30B11/02B30B11/08B30B11/34B60J7/05B60R13/02
CPCA61J3/06A61J3/10A61K9/2054A61K9/2081A61K9/2095Y10T428/29B30B11/08B30B11/34B60R13/0206B60R13/0212B30B11/02B30B11/00
InventorOZEKI, YUICHIKONDO, YOSHIYAWATANABE, YUKINAO
OwnerSANWAKAGUKU KENKYUSHO CO LTD