Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicinal Composition of Extract of Seed of Emblica Officinalis and Method of Preparing the Same

a technology of emblica officinalis and extract, which is applied in the directions of biocide, hair cosmetics, plant/algae/fungi/lichens ingredients, etc., can solve the problems of statins not being effective in the treatment of patients with chylomicronemia, failure to achieve the desired goal and reducing harmful ldl cholesterol , the effect of safe lipid lowering

Inactive Publication Date: 2015-04-09
ARJUNA NATURAL PTE LTD
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent is about a medicinal composition made from extracts of the seeds of Emblica officinalis. This composition has various benefits for reducing cholesterol, preventing heart disease, and improving HDL levels in humans. Compared to extracts made from the fruits of Emblica officinalis, the seeds have better results in terms of reducing cholesterol and preventing heart disease. The patent also provides a method for preparing these seeds and a method for using them as a nutraceutical or pharmaceutical. Overall, the patent describes a beneficial composition that can help in reducing the risk of heart disease and improving heart health.

Problems solved by technology

Statins also reduce the serum TG levels; but they are often insufficient.
Statins are ineffective in the treatment of patients with chylomicronemia.
Thus, diets alone or in conjunction, with lipid lowering drugs fail to yield the desired goal of safe lipid lowering.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicinal Composition of Extract of Seed of Emblica Officinalis and Method of Preparing the Same
  • Medicinal Composition of Extract of Seed of Emblica Officinalis and Method of Preparing the Same
  • Medicinal Composition of Extract of Seed of Emblica Officinalis and Method of Preparing the Same

Examples

Experimental program
Comparison scheme
Effect test

example 1

Method of Preparation of Ethyl Acetate Extract of Methanol Extract of Seed of Emblica officinalis (Amla Seed Extract)

[0074]Fresh fruits of Emblica officinalis (Amla) were collected (500 Kg). Fruits were deseeded by deseeding machine and fresh seeds (75 Kg) were crushed through roller mill. 95% Methanol in an amount 2 times the quantity of crushed seeds was added to the crushed seeds to form a mixture for methanol extraction. The extraction was performed using an extractor with reflux condenser. The bottom of the extractor was fitted with a polypropylene (100 microns) filter cloth. The mixture was re fluxed for one hour at 65° C. to obtain a first residue and supernatant. The residue and supernatants were separated by draining out the supernatant from the extractor bottom through the polypropylene filter cloth using a centrifugal pump. After the first extraction, the first residue was further extracted with two times the quantity of methanol at 65° C. to get second residue and supern...

example-2

Method of Preparation of Ethyl Acetate Extract of Seed of Emblica officinalis (Amla Seed Extract)

[0076]Fresh fruits of Emblica officinalis were collected (500 Kg). Fruits were deseeded by deseeding machine and fresh seeds (75 Kg) were crushed through roller mill. Crushed seeds were filled in the Soxhlet extractor and extracted with ethyl acetate (300 L). The extraction was carried out for 5 hrs at a temperature of about 78° C. After the completion of extraction, the supernatant was filtered and concentrated in an Agitated thin film evaporator (ATFE) at a temperature of 75° C. to form concentrated ethyl acetate extract. Concentrated ethyl acetate extract was dried under vacuum at above 500 mm of mercury to gel 2 Kg of powder of ethyl, acetate extract of seed of Emblica Officinalis.[FIG. 2]

example-3

[0077]Method of Preparation of Pectinase Treated Water Extract of Fruits of Emblica Officinalis (Amla)

[0078]Fresh fruits of Emblica officinalis were collected (100 Kg). Fresh fruits of Emblica officinalis were pulped with demineralized water to create slurry. The slurry was treated with pectinase and then filtered to obtain a solution. The solution, was concentrated and dried under vacuum. Dried product (5 kg) was pulverized and sieved through 30 meshes to obtain a powder of a pectinase treated water extract of Emblica officinalis.[FIG. 3]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
concentrationsaaaaaaaaaa
Login to View More

Abstract

A composition having an extract of seed of Emblica officinalis. Methods of preparing extract of seed of Emblica officinalis. An amla seed blend composition having various ratios of extracts of seeds of Emblica officinalis. Nutraceutical or pharmaceutical methods for decreasing the total cholesterol, decreasing triglyceride, decreasing blood glucose level, enhancing HDL-C levels, increasing the HDL-C level to total cholesterol ratio, lowering LDL-C levels, decreasing the CRP level, decreasing the intima media thickening, reducing hair fall in mammals especially human beings. The extract of seed of Emblica officinalis, or the amla seed blend composition is more effective compared to extracts prepared from fruits of Emblica officinalis.

Description

[0001]This application is a continuation of International Application No. PCT / IN2014 / 000642 filed Oct. 7, 2014, which claims priority of Indian Provisional Application Ser. No. 4565 / CHE / 2013 filed Oct. 8, 2013.FIELD[0002]The disclosure relates a medicinal composition of the extract of seed of Emblica officinalis, a method of preparing a composition consisting of extract of seed of Emblica officinalis more particularly which has application as a nutraceutical or pharmaceutical for reducing the total cholesterol reducing triglyceride, reducing blood glucose level, enhancing HDL-Cholesterol, increasing the HDL-Cholesterol to total cholesterol ratio, lowering LDL-Cholesterol levels, reducing the CRP level, decreasing the intima media thickening, reducing hair fall in mammals especially human beings. The composition is effective even at lower dosage for reducing the total cholesterol, reducing triglyceride, reducing blood glucose level, enhancing HDL-Cholesterol levels, increasing the HD...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61K36/47A61Q7/00A61K8/97
CPCA61K36/47A61Q7/00A61K8/97A61K31/045A61K31/192A61K31/201A61K31/202A61K31/575A61K8/9789A61K2300/00A61K36/185B01D11/02
Inventor ANTONY, BENNY
Owner ARJUNA NATURAL PTE LTD