Multiple electrode lead and a system for deep electrical neurostimulation including such a lead

a multi-electrode technology, applied in the direction of external electrodes, internal electrodes, therapy, etc., can solve the problems of multiple risks and side effects of surgery, and achieve the effect of minimizing the risks and side effects of such treatment and effective treatmen

Active Publication Date: 2011-08-02
COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0015]An object of the invention is thus to provide a lead for deep electrical neurostimulation making it possible, at least in the context of certain applications, such as stimulating the CG25 region, to obtain more effective treatment, while minimizing the risks and the side effects of such treatment.

Problems solved by technology

However, that has the drawback of allowing only a very small region of brain tissue to be stimulated, whereas in order to obtain more effective treatment it would be desirable to be able to act on a target of larger volume.
Implanting a plurality of leads directed at distinct points of a common target region of relatively large volume is indeed possible, but that multiplies the risks and the side effects of the surgery.

Method used

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  • Multiple electrode lead and a system for deep electrical neurostimulation including such a lead
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  • Multiple electrode lead and a system for deep electrical neurostimulation including such a lead

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Embodiment Construction

[0039]The lead 1 of the invention essentially comprises two portions: a substantially rectilinear rod 10 and a blade 20 in the form of a sickle or kidney bean, secured to a so-called “distal” end of said rod 10 and in alignment therewith, so as to constitute an extension. Both the rod 10 and the blade 20 are made of biocompatible material, preferably a relatively flexible material such as silicone, siloxane, polyurethane, polyvinyl chloride, benzocyclobutene (BCB), polyimide, and parylen. The rod 10 and the blade 20 are preferably made as a single piece, but that is not essential.

[0040]The lead 1 presents a structure that is substantially planar. The rod 10 presents a section that is at least approximately rectangular, as shown in FIGS. 3 and 4, having thickness E generally lying in the range 25 μm to 3 mm, and preferably lying in the range 50 μm to 2 mm, and a width L generally lying in the range 10 mm to 40 mm, and preferably in the range 15 mm to 30 mm. In a variant, the rod 10 m...

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Abstract

A lead for deep electrical neurostimulation comprising a rod of biocompatible material and a blade, also of biocompatible material, secured to one end of the rod and in alignment therewith. The blade presents two main faces and a plurality of electrodes disposed on at least one of the two main faces in a two-dimensional configuration. The electrodes are connected to conductor elements disposed inside or on a surface of said rod. A deep electrical neurostimulation system comprising an electrical pulse generator connected to at least one lead of the above-described type is also disclosed.

Description

[0001]The invention relates to a lead for deep electrical neurostimulation, and more particularly for deep brain electrostimulation. The invention also relates to a system for deep electrical neurostimulation and including at least one such lead.BACKGROUND OF THE INVENTION[0002]Deep brain stimulation is a therapeutic technique comprising implanting a medical appliance known as a brain stimulator that serves to send electrical pulses to specific regions of the brain. For example, stimulation of the nuclei of the thalamus or of the hypothalamus can be used for treating motor disorders such as tremor, caused in particular by Parkinson's syndrome; in this context, reference can be made to the following articles:[0003]P. Krack, P. Pollak, P. Limousin, A. Benzzaous, A. L. Benabid, The Lancet, Vol. 350, Dec. 6, 1977; and[0004]A. L. Benadid et al., Acta Neurochirurgica suppl., Vol. 58, pp. 39-44, 1993.[0005]It has also been envisaged to stimulate the posterior hypothalamic nucleus for treat...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): A61N1/05
CPCA61N1/0529A61N1/0531
Inventor BENABID, ALIM LOUISSAUTER-STARACE, FABIENCAILLAT, PATRICE
Owner COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
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