The invention discloses a cotton cloth selling storage device with a dust removal effect. The storage device comprises a device body and a driving motor, wherein a plurality of open placing grooves arranged side by side are formed in the device body; a first air guide hole and a second air guide hole are formed at the position, above and below the open placing grooves, in the device body respectively; and an air outlet end of the first air guide hole and an air inlet end of the second air guide hole both communicate with the outside. According to the cotton cloth selling storage device with the dust removal effect, through matched use among the driving motor, a first driven rod, a first bevel gear, a bearing seat, a fixed rod, a second driven rod, fan blades, a second bevel gear, the second air guide hole, a second chamber, a fourth driven rod, a pressing plate, a second return spring, a sliding groove, a through hole, a sliding rod, a connecting rod, fifth air guide holes, sixth air guide holes and seventh air guide holes, gas is continuously sprayed outwards when a cabinet door is opened, dust is prevented from entering and being absorbed on cotton cloth, and therefore normal sale of the cotton cloth is guaranteed.