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Compound hedgehog hydnum dispersion tablet for treating gastrosia, and its preparing method

A technology for dispersible tablets and compound recipes, applied in the field of compound Hericium erinaceus dispersible tablets and their preparation, can solve the problems of inconvenient taking, special odor, etc., and achieve the effects of stable quality, no side effects, curative effect, and wide applicability to the crowd.

Inactive Publication Date: 2008-10-29
朱经州
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a compound hericium ericaceus dispersible tablet for treating stomach diseases and a preparation method thereof, solve the problem that the product has a special smell when taken orally, and solve the problem that the existing product is inconvenient to take; use the preparation method provided by the invention to prepare The product has no peculiar smell, stable quality, easy to take, fast absorption, high bioavailability, and small adverse reactions, which can overcome the shortcomings of the existing technology

Method used

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  • Compound hedgehog hydnum dispersion tablet for treating gastrosia, and its preparing method
  • Compound hedgehog hydnum dispersion tablet for treating gastrosia, and its preparing method
  • Compound hedgehog hydnum dispersion tablet for treating gastrosia, and its preparing method

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Effect test

Embodiment 1

[0059] Embodiment 1 of the present invention: take Hericium erinaceus dry product, add warm water and soak for 30 minutes, stir, boil for 1 hour at a constant temperature, cool and filter, add water to the filter residue and boil for 1 hour at a constant temperature, filter, combine the filtrates, and vacuum concentrate to liquid extract , add 95% ethanol to 75% alcohol content, put it in a cold storage below 4°C for 48 hours, filter, dry in a vacuum oven to obtain Hericium erinaceus dry extract; weigh Hericium erinaceus dry extract 45g, sucralfate 20g, magnesium trisilicate 10g, bismuth subnitrate 8g, mixed and milled, added CMS-Na disintegrant 2g, granulated with 95% ethanol, dried at 65°C, passed through a 80-mesh sieve, Then add 6g of CMS-Na disintegrant, 5g of microcrystalline cellulose anti-humidity agent and 2g of micropowder silica gel lubricant, mix, and press into dispersible tablets to obtain the product.

Embodiment 2

[0060] Embodiment 2 of the present invention: take Hericium erinaceus dry product, add warm water and soak for 50 minutes, stir, boil at a constant temperature for 0.5 hours, cool and filter, add water to the filter residue and boil at a constant temperature for 0.5 hours, filter, combine the filtrates, and vacuum concentrate to a liquid extract , add 80% ethanol to 60% alcohol content, put it in a cold storage below 4°C for 12 hours, filter, dry in a vacuum oven to obtain Hericium erinaceus dry extract; weigh Hericium erinaceus dry extract 40g, sucralfate 16g, magnesium trisilicate 5g, bismuth subnitrate 6g, mix and grind, add CMS-Na disintegrant 3g, granulate with 80% ethanol, dry at 50°C, pass through a 60-mesh sieve, Then add 4g of CMS-Na disintegrant, 3g of microcrystalline cellulose anti-humidity agent and 1g of micropowder silica gel lubricant, mix, and press into dispersible tablets to obtain the product.

Embodiment 3

[0061] Embodiment 3 of the present invention: take Hericium erinaceus dry product, add warm water to soak for 15 minutes, stir, boil at a constant temperature for 1.5 hours, cool and filter, add water to the filter residue and boil at a constant temperature for 2.0 hours, filter, combine the filtrates, and vacuum concentrate to a liquid extract , add 98% ethanol to 80% alcohol content, put it in a cold storage below 4°C for 60 hours, filter, dry in a vacuum oven to obtain Hericium erinaceus dry extract; weigh Hericium erinaceus dry extract 60g, sucralfate 30g, magnesium trisilicate 20g, bismuth subnitrate 10g, mix and grind, add CMS-Na disintegrant 5g, granulate with 98% ethanol, dry at 70°C, pass through a 100-mesh sieve, Then add 4g of CMS-Na disintegrating agent, 8g of microcrystalline cellulose anti-humidity agent and 4g of micropowder silica gel lubricant, mix, and press into dispersible tablets to obtain final product.

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Abstract

The present invention relates to a compound monkey head mushroom dispersing tablet for curing gastropathy and its preparation method. Said invention has the functions of alleviating pain, nourishing stomach and raising immunity and can be used for curing the diseases of gastroduodenal ulcer and chronic gastritis, its total effective rate can be up to 96.8%. Said invention also has a certain therapeutic effect for carcinoma of esophagus and carcinoma of stomach. Said dispersing tablet is made up by using dried monkey head mushroom extract, ulcerlmin, magnesium trisilicate, bismuth subnitrate, disintegrant, lubricant and moisture-resisting agent. Said invention also provides its preparation method.

Description

Technical field: [0001] The invention relates to a compound hericium ericaceus dispersible tablet for treating stomach diseases and a preparation method thereof, belonging to the technical field of medicines. Background technique: [0002] Stomach trouble is a kind of common disease, frequently-occurring disease, is used at home and abroad at present the medicine of stomach trouble a lot, and traditional Chinese medicine preparation also has western medicine preparation. Western medicine preparations usually take effect quickly, but they often have side effects, and are prone to relapse after drug withdrawal, while traditional Chinese medicine preparations have stable curative effects and few side effects, but their treatment courses are longer. The applicant’s unit before the restructuring: Zhejiang Yuerkang Pharmaceutical Co., Ltd. is the earliest unit in China to study Hericium ericaceus preparations for the treatment of stomach diseases; after the restructuring, the name...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/06A61P1/04
Inventor 朱经州
Owner 朱经州
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