The invention discloses a Chinese medicinal preparation for treating duodenal ulcer, which comprises the following Chinese herbal medicines in part by weight: 10 to 20 parts of astragalus, 10 to 20 parts of peach seed, 10 to 20 parts of bletilla, 10 to 20 parts of nutgrass galingale rhizome, 10 to 20 parts of white paeony root, 10 to 20 parts of largehead atractylodes rhizome, 10 to 20 parts of Indian buead, 10 to 20 parts of honey-fired liquoric root, 10 to 20 parts of emblic leafflower fruit, 10 to 20 parts of Chinese gall, 10 to 20 parts of combined spicebush root, 10 to 20 parts of tangerine peel, 10 to 20 parts of chicken's gizzard-membrane, 10 to 20 parts of notoginseng root, 10 to 20 parts of bupleurum, 10 to 20 parts of sanguisorba root, 10 to 20 parts of ginger, 10 to 20 parts of rosewood heart wood, 10 to 20 parts of root of red-rooted salvia, 10 to 20 parts of cuttlefish bone and 10 to 20 parts of cinnamomvine. The Chinese medicinal preparation has the effects of calming liver and regulating flow of qi, tonifying spleen, lung and kidney, tonifying middle-Jiao and qi and stopping bleeding and preventing or arresting vomiting, is mainly used for treating discomfort in spleen and stomach and weakness of the spleen and the stomach, and fulfills the aims of stopping diarrhea and diminishing inflammation, relieving spasm and pain, improving local blood circulation and metabolism, enhancing the immunologic function of intestinal tracts and promoting ulcer healing. The Chinese medicinal preparation has a simple preparation process, small toxic or side effects and low cost, and is convenient to administrate and easy to prepare.