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Yunan red drug tablet , its preparation method and use

A technology of pills and red medicines, applied in the field of pharmaceutical compositions, which can solve problems such as unfavorable clinical drug safety, poor control of dosage, long capsules, etc.

Inactive Publication Date: 2004-03-17
YUNNAN PHYTOPHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Due to the diversity of clinical patients and their own specific conditions, the existing dosage forms cannot meet the needs of clinical drug diversity
As far as Yunnan Hongyao Capsule is concerned, first, the capsule shell is filled with fine powder of compound medicinal materials, and the moisture and pathogenic bacteria are not easy to be completely removed, and the capsule itself is poor in moisture-proof, light-proof and airtight, and loose after filling the capsule. The medicinal powder of traditional Chinese medicine is easy to absorb moisture and deteriorate, which is not conducive to the safety of clinical medication; second, although capsule shells are commonly used pharmaceutical excipients, high-quality capsule shells are still expensive and increase the burden on patients, so they are not economical
Furthermore, the capsules are long and difficult to swallow for some patients.
[0005] Yunnan Hongyao powder is made by putting the fine powder of compound medicinal materials for multiple doses into a bottle. It is difficult to control the dose for each dose, and the loose powder is easy to absorb moisture and deteriorate, and is easy to be contaminated, which is not conducive to ensuring the safety and effectiveness of clinical medication.
Furthermore, the powder is a direct entrance of the powder, and the patient is prone to discomfort such as choking.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] The parts by weight of raw materials of Yunnan red medicine are: Panax notoginseng 20, Chonglou 55, Zijinlong 10, Cannabis 15, Jintiesuo 10, Sliding leaf Dieda 20, Yu grape root 20, Zhihuangcaowu 35, Shichangpu 5 , Southwest Huangling 20. The parts by weight of Yunnan Hongyao Tablets are: Yunnan Hongyao 216, microcrystalline cellulose 5, sucrose powder 18, dextrin 12, magnesium stearate 3, talcum powder 3, carboxypropyl methylcellulose 60% ethanol liquid Appropriate amount.

[0060] Remove the foreign matter and impurities from the Chinese herbal medicines, quickly wash away the sediment with running water, filter the water, dry below 80°C until the water content is 2%, pulverize, pass through an 80-mesh sieve, and set aside; according to the Yunnan The parts by weight of the composition of the red medicine, each Chinese herbal medicine powder is weighed and placed in a mixer, mixed until the color is uniform, passed through a 40-mesh sieve, and mixed for 20 minutes to...

Embodiment 2

[0062] The parts by weight of raw materials of Yunnan red medicine are: Panax notoginseng 30, Zhonglou 65, Zijinlong 15, Cannabis 20, Jintiesuo 15, Sliding leaf Dieda 28, Yu grape root 30, Huangcaowu 40, Shichangpu 10 , Southwest Huangling 30; The parts by weight of Yunnan Hongyao Tablets are: Yunnan Hongyao 283, microcrystalline cellulose 8, sucrose powder 30, dextrin 15, magnesium stearate 3, talcum powder 3, carboxypropylmethyl An appropriate amount of cellulose 60% ethanol solution.

[0063] Production process is identical with embodiment 1.

Embodiment 3

[0065] The parts by weight of raw materials of Yunnan red medicine are: Panax notoginseng 25, Zhonglou 62.5, Zijinlong 12.5, Cannabis 18.75, Jintiesuo 12.5, Sliding leaf Dieda 23.75, Yu grape root 25, Huangcaowu 37.5, Shichangpu 7.5 , Southwest Huangling 25.

[0066] The parts by weight of Yunnan Hongyao tablets are: 270 Yunnan Hongyao, 6.5 microcrystalline cellulose, 24 sucrose powder, 13.5 dextrin, 3 magnesium stearate, 3 talcum powder, 60% ethanol solution of carboxypropyl methylcellulose Appropriate amount.

[0067] Production process is identical with embodiment 1.

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PUM

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Abstract

Yunnan Hongyao tablet is prepared with Yunnan Hongyao 210-283 (in weight portions, the same below), avicel 5-8, cane sugar powder 18-30, dextrin 12-15, magnesium stearate 3, talcum powder 3, CMC in 60 % and alcohol in proper amount. Where, Yunnan Hongyao consists of ten kinds of Chinese medicinal materials, including notoginseng, Chinese paris rhizome, dactylicapnos root, falcate dolichos root or leaf, tuniclike psammosilene root, etc. Yunnan Hongyao tablet is safe, non-toxic, strong in pharmacological effect and wide in indications, and may be used widely in preparing medicines for preventing and treating gastroduodenal ulcer, upper respiratory tract hemorrhage and functional metrorrhagia, stopping pain and resisting rheumatism.

Description

Technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition made from plant Chinese herbal medicines as main raw materials. At the same time, the present invention also relates to a preparation method of the pharmaceutical composition and its application in the field of pharmacy. Background technique [0002] In daily life, gastric ulcer bleeding, bronchiectasis hemoptysis, dysfunctional uterine bleeding, menorrhagia, fundus hemorrhage and other diseases are common and frequently-occurring diseases, which endanger the lives of patients in severe cases. But in the prior art, still do not have the specific medicine to these diseases, especially lack the Chinese medicinal preparation that is convenient to take, and toxic side effect is little, and therapeutic effect is remarkable. [0003] Yunnan Hongyao, formerly known as Yunnan Qilong Powder, is a Chinese patent medicine produced by Yunna...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/04A61P7/04A61P15/00A61P29/00
Inventor 周敏朱红涛马嵘白运辉
Owner YUNNAN PHYTOPHARML
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