57 results about "Mastic Gum" patented technology

A food composition includes allulose having a concentration of about 60% to about 70% by weight, a cocoa product having a concentration of about 20% to about 30% by weight, and at least one natural plant resin having a concentration of about 0.37% to about 2.19% by weight. The at least one natural plant resin may be mastic gum and / or mastic powder. The food composition may further include a combination of plant-derived biominerals and / or antioxidants as active ingredients. A confectionary product made with the food composition is also disclosed.

The disclosed composition consists of 15 mg Ferula asafetida (Hing) oil as an active ingredient, 85 mg Frankincense oil and 400 mg coconut oil as in-active ingredients in an enteric coated HPMC capsule form. The process of preparation consists of steps of blending asafetida (hing) oil with Frankincense oil and coconut oil followed by dispensing the blended oils into empty HPMC capsule shell, which are automatically filled in liquid filling machine. Further a banding solution containing 0.025 ml HPMC (surfactant), 2.8 mg IPA (Binding Agent) and 0.03 mg Chocolate brown color (colorant) are filled into the bath of band sealing machine at room temperature where the hing oil containing capsules are band sealed. The disclosed oral formulation in the form of HPMC capsule is natural, low cost, highly efficacious and quick in management primary dysmenorrhea.

The invention discloses a traditional Chinese medicine combination effective part capable of improving diabetic peripheral neuropathy. The traditional Chinese medicine combination effective part is prepared from a volatile oil effective part, a water-soluble effective part and an alcohol-soluble effective part, the effective part of the volatile oil comprises alpha-ocimene, alpha-santalene, bisabolol, beta-bisabolol and nerolidol; the water-soluble effective part comprises salvianolic acid A, salvianolic acid B and tanshinol; the alcohol-soluble effective part is prepared from Z-ligustilide, alpha-masticinic acid, beta-masticinic acid, tanshinone IIA, and 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone, and the alcohol-soluble effective part is prepared from the following raw materials in parts by weight: 2-methoxy-5-acetyl-furangermacane-1 (10)-ene-6-ketone. The traditional Chinese medicine composition effective part provided by the invention can regulate blood sugar, improve the conduction speed of sciatic nerves, repair damaged tissues, inhibit oxidative stress reaction, resist inflammation and relieve pain, so that the diabetic peripheral neuropathy is improved, the curative effect is reliable, the safety is good, the adverse reaction is low, and the traditional Chinese medicine composition effective part can be used for preparing a medicinal preparation for improving the diabetic peripheral neuropathy.

The present application belongs to the technical field of traditional Chinese medicine composition, and relates to a traditional Chinese medicine transdermal external preparation for treating vulvar hypopigmentation disease. The preparation is a paste prepared by mixing traditional Chinese medicine powder and horse oil. The traditional Chinese medicine powder is composed of the following raw materials by weight: Xuchangqing 10-12, Pugongying 10-15, Difusiduo 12-15, Tuzifuding 12-15, Baiji 10-15, Huzhang 9-12, Quansie 6-10, Diyu 10-12, Xuezhi 10-12, Danggui 6-10, Rushang 6-10, Miedu 6-10, Bingpian 1-3. The traditional Chinese medicine transdermal external preparation has definite and significant effects on vulvar hypopigmentation disease, especially in relieving intractable pruritus, promoting pigment recovery and improving skin sclerosis / atrophy. The traditional Chinese medicine transdermal external preparation has high safety, few adverse reactions and low recurrence rate.

The invention provides a traditional Chinese medicine extract with a folliculitis treatment effect, a preparation method of the traditional Chinese medicine extract and prepared bacteriostatic shampoo, and belongs to the technical field of daily necessities. The traditional Chinese medicine extract is prepared from the following raw materials in parts by mass: 5 to 20 parts of rhizoma coptidis, 5 to 20 parts of cortex phellodendri, 5 to 20 parts of radix scutellariae, 5 to 20 parts of vinegar frankincense, 5 to 20 parts of vinegar myrrh, 5 to 20 parts of radix et rhizoma rhei, 5 to 20 parts of rhizoma polygoni cuspidati, 5 to 20 parts of radix stemonae and 5 to 20 parts of herba taraxaci. By optimizing the compatibility and extraction process of a traditional Chinese medicine formula and combining the modern preparation technology, the invention aims to provide a traditional Chinese medicine hair washing therapeutic agent which is efficient in permeation, long-acting in bacteriostasis, safe, mild and strong in cleaning power, so as to overcome the defects of current chemical hair washing products in the field of folliculitis treatment.

The present invention discloses a pain relieving plaster preparation process and a filtration treatment system, and relates to the field of medical equipment, the pain relieving plaster comprises the following production raw materials by mass ratio (W / W%): 3.0-5.0% of menthol; 0.5 to 1.0 part of carbomer; 0.3 to 0.7 part of camphor; 0.5 to 0.9 part of triethanolamine; 23.0 to 29.0 parts of isopropyl alcohol; 0.2 to 0.3 part of an arnica flower extract; 4.0 to 5.0 parts of glycerol; 0.4 to 0.6 part of isopropyl myristate; 0.1 to 0.2 part of a calendula flower extract; 0.01 to 0.03 part of VE (Vitamin E) acetate; 0.1 to 0.2 part of melissa officinalis leaf extract; 0.005 to 0.015 part of aloe barbadensis leaf juice; 0.1 to 0.3 part of burdock extract; 0.4-0.6% of a tea leaf extract; 0.1-0.3 part of a paraguay tea leaf extract; 0.04 to 0.06 part of olibanum serratum extract; 0.05 to 0.15 part of a methyl methacrylate cross-linked polymer; 0.001 to 0.003 part of a pigment; and the rest is water. According to the invention, menthol is taken as a main active component for relieving pain and is matched with components such as skin-care grease, an ointment product with a pain-relieving effect is produced through a physical mixing process, and the quick-acting formula can deeply permeate and quickly dry and is wide in application range.

The intraoral cleaning tablet has a chewable gum to stimulate saliva and a fibrous ingestible material in the form of dried apple peel. The dried apple peel embedded within the chewable gum in order to clean the teeth. The chewable gum is plastic-free and biodegradable, comprised of ingredients such as mastic or chicle.

The invention provides an external medicine composition for clearing heat, diminishing swelling and dispersing blood stasis as well as application and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine formulas. The external medicine composition for clearing heat, diminishing swelling and dispersing blood stasis is prepared from the following raw material medicine components in parts by weight: 5 to 8 parts of raw cortex phellodendri, 2 to 5 parts of borneol, 8 to 12 parts of radix paeoniae rubra, 4 to 8 parts of radix notoginseng slices, 4 to 6 parts of fried ground beeltle, 2 to 4 parts of prepared myrrh, 2 to 4 parts of prepared frankincense, 5 to 8 parts of prepared rhizoma arisaematis, 8 to 12 parts of fructus liquidambaris and 8 to 12 parts of radix angelicae. , 8-12 parts by weight of mint, and 8-12 parts by weight of radices trichosanthis. The external medicine composition for clearing heat, diminishing swelling and dispersing blood stasis is prepared from traditional Chinese medicinal materials which have the effects of clearing heat, cooling blood, dispersing blood stasis, dispersing swelling and promoting blood circulation, can avoid the risk of bleeding and swelling aggravation during use in an acute stage, and realizes safe and effective early intervention of injury of ankle joints or other parts in the acute stage, so that the rehabilitation time of a patient is shortened.

The application discloses a traditional Chinese medicine external application powder and a preparation method and application thereof. The traditional Chinese medicine external application powder is prepared from the following raw medicinal materials in parts by weight: Herba Reineckiae 10-14 parts, Herba Vaccariae 18-22 parts, Radix et Rhizoma Rhei 4-6 parts, Olibanum 8-12 parts, Dried Dragon's Blood 4-6 parts, Myrrha 8-12 parts, Fructus Zanthoxyli 4-6 parts, Fructus Amomi Rotundus 13-17 parts, Cortex Mori 8-12 parts, Resina Commiphorae 8-12 parts and Mirabilite 0.5-1.5 parts. The traditional Chinese medicine external application powder has the effects of activating blood circulation to dissipate stasis, removing swelling and pain, relaxing tendons and recovering injury, and removing stasis without damaging normal body functions. The traditional Chinese medicine external application powder is used in the clinical treatment of 8 cases of acute sprain of joints accompanied by edema of soft tissues, and the swelling and pain are obviously relieved within one treatment course (5 times), and the joint function is recovered, and the total effective rate and the cure rate are both 100%. In the 8 cases, the symptoms of 7 cases disappear in 5 days, and the swelling and pain of 1 case of acute exacerbation of old injury are basically relieved in 5 days, and the old injury is cured in 3 days. The traditional Chinese medicine external application powder has the advantages of fast effect, short treatment course, good effect on acute injury and recurrence of old injury.

The invention discloses a formula and a preparation method of a quick-acting analgesic tincture external spraying agent, and belongs to the technical field of external spraying agents, the quick-acting analgesic tincture external spraying agent comprises the following raw materials in parts by weight: a group A: 25kg of radix clematidis, 20kg of radix saposhnikoviae, 20kg of rhizoma zingiberis, 20kg of radix angelicae, 20kg of rhizoma drynariae, 20kg of notopterygium root, 15kg of corydalis tuber, 15kg of radix aconiti preparata, 15kg of radix aconiti kusnezoffii preparata and 15kg of frankincense preparata; the traditional Chinese medicine is prepared from 15 kilograms of prepared myrrh, 15 kilograms of ligusticum wallichii, 10 kilograms of ephedra, 10 kilograms of asarum, 5 kilograms of saffron crocus (240 kilograms of 15 parts) and 1200 kilograms of ethanol. The group B comprises 15 kilograms of camphor, 5 kilograms of storax oil, 3 kilograms of vanillyl butyl ether and ethanol (the dosage is 300-900% of the total weight of the medicines), the prepared'ten-full-pain quick-napping 'tincture is generally used for various arthralgia pains caused by wind-cold-dampness stasis, and aims at the etiology and symptoms of arthralgia, cold-dampness pains, blood stasis pains, spasm pains and wind-excess channeling pains, medicine symptoms are combined, both symptoms and root causes are taken into consideration, and the traditional Chinese medicine tincture can be used for treating various arthralgia pains caused by wind-cold-dampness stasis. The composition has the advantages of quick transdermal effect, quick effect, broad effect, special effect, safety and convenience, and meets the fast-paced life of modern people and the high requirements on health, high efficiency, convenience and safety. The promotion and popularization of the invention will surely produce great social and economic benefits.

The present invention relates to the use of natural protectants comprising a mastic extract and optionally a second component to prevent microbial growth and preserve a product. The invention also relates to the use of natural protectants comprising quinic acid or a salt thereof, ethyl lauroyl arginate or a salt thereof, and optionally a third component to prevent microbial growth and preserve a product.

The invention discloses a pharmaceutical composition for bone diseases and bone fractures. The pharmaceutical composition is prepared from the following raw material medicines in parts by weight: 15-25 parts of calcined native copper, 10-20 parts of vinegar myrrh, 10-20 parts of vinegar frankincense, 3-10 parts of cornu cervi degelatinatum, 3-10 parts of white dipsacus, 3-10 parts of safflower carthamus, 15-25 parts of ground beetles, 3-10 parts of white mulberry root-bark and 3-10 parts of dragon's blood. The fine powder of the pharmaceutical composition and pharmaceutically acceptable auxiliary materials or auxiliary components are prepared into an external preparation. The patch has good biocompatibility with skin, and the hydrophilic polymer matrix has air permeability, perspiration resistance, no sensitization and no irritation; the drug release performance is good, the affinity with the skin is strong, the hydration effect of the cuticle can be improved, and the transdermal absorption of the drug is facilitated; a transdermal absorption controlled release technology is applied, so that the blood concentration is stable, and the drug effect is lasting.

The present application relates to the technical field of Qizixuexu agent sticking, especially to a Qizixuexu acupoint sticking and a preparation method thereof, the Qizixuexu acupoint sticking comprises the following raw materials and weight parts, Anarhichas lupus, 3-7 parts; red peony root, 8-12 parts; peach kernel, 8-12 parts; gardenia, 8-12 parts; myrrh in vinegar, 8-12 parts; olibanum in vinegar, 8-12 parts; baizhi, 8-12 parts; sanqi, 8-12 parts; rhubarb, 8-12 parts; xiangfu, 8-12 parts; corydalis, 8-12 parts; safflower, 8-12 parts. The present application improves the Qizixuexu related symptoms of the elderly patients by preparing a specific Qizixuexu acupoint sticking, plays a role in multiple targets and multiple directions, and improves the treatment effect of the patients.

The invention belongs to the technical field of important compositions, and particularly relates to a traditional Chinese medicine composition for treating muscle and bone diseases, a traditional Chinese medicine preparation and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials: radix angelicae pubescentis, ligusticum wallichii, rhizoma sparganii, rhizoma atractylodis macrocephalae, peach kernels, radix angelicae sinensis, flos daturae, radix paeoniae rubra, radix angelicae, unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, unprocessed rhizoma pinelliae, unprocessed rhizoma arisaematis, flos carthami, unprocessed radix rehmanniae, radix et rhizoma rhei, fructus forsythiae, trogopterus dung, unprocessed radix astragali, unprocessed semen strychni, rhizoma et radix notopterygii, unprocessed radix glycyrrhizae, drynaria baronii, frankincense, myrrh and storax. Aiming at the technical problems of single effect and limited curative effect of the existing plaster, the plaster disclosed by the invention combines the functions of eliminating evil and strengthening the body resistance through scientific formula compatibility, and realizes the synergistic effect of multiple effects of clearing heat, tonifying qi, activating blood, dredging collaterals and the like, so that the treatment of the plaster is more comprehensive and deep, and the plaster has a remarkable curative effect on chronic and intractable muscle and bone diseases.

The present invention relates to the use of multifunctional protectants comprising (i) hydroxyacetophenone with (ii) at least one of natural 1,3-propanediol and a mastic extract to protect a formulation from biodegradation. The present invention also relates to the use of a protectant comprising (i) hydroxyacetophenone with (ii) at least one of vitamin B5, vitamin C, and vitamin E to protect a formulation from biodegradation.

The invention discloses a yang-warming and cold-dispelling health-care liquid and a preparation method thereof. The aconitine content is less than or equal to 0.015 mg / mL and the heat effect lasting time is more than or equal to 8 hours by combining the radix aconiti carmichaeli-rhizoma zingiberis toxicity attenuation synergistic compatibility with the phase change temperature control technology. The transdermal rate of the masticinic acid is increased by 3.5 times by innovatively adopting a micro-jet nanocrystallization process, and the production safety is ensured by matching with near-infrared online monitoring. Animal experiments prove that microcirculation disturbance can be remarkably improved (the blood flow speed is increased by 178%), and the traditional Chinese medicine composition is suitable for local warming and dredging conditioning of people with yang-deficiency constitution.

The invention relates to a traditional Chinese medicine ointment for treating sores and ulcers caused by heat toxin accumulation and a preparation method of the traditional Chinese medicine ointment. Comprising the following raw materials: 10-15 g of honeysuckle, 10-15 g of spina gleditsiae, 10-15 g of thunberg fritillary bulb, 8-10 g of radix angelicae, 10-15 g of radix paeoniae rubra, 9-12 g of radix trichosanthis, 5-7 g of frankincense, 5-7 g of myrrh, 8-10 g of radix saposhnikoviae, 10-15 g of pericarpium citri reticulatae, 8-10 g of angelica sinensis, 8-10 g of lumbricus, 5-8 g of turtle shell, 10-15 g of herba patriniae, 10-15 g of coptis chinensis, 5-7 g of bletilla striata, 5-7 g of liquorice, 50-70 g of beewax, 5-8 g of borneol, 25-35 g of mirabilite and 450-500 g of ground oil. According to the traditional Chinese medicine ointment disclosed by the invention, in clinical observation of treating sores and ulcers caused by the heat toxin accumulation syndrome, the 3-day cure rate is 55%, the 5-day cure rate is 95%, the effective rate is 100%, and the traditional Chinese medicine ointment has a good effect on the sores and ulcers caused by the heat toxin accumulation syndrome.

The invention provides methods and products for use in treating hyposalivation and / or xerostomia in an individual. The invention further provides methods for increasing salivation in an individual. The methods comprise administering a therapeutic selected from alpha-pinene and / or mastic resin. The invention further provides oral adhering troches comprising said therapeutic.

Compositions comprising hydroxytyrosol and masticinic acid are provided. Compositions comprising a synergistic combination of hydroxytyrosol and 3-O-acetyl-11-one-beta-masticinic acid are described. The hydroxytyrosol can be derived from an olive extract, and the 3-O-acetyl-11-keto-beta-boswellic acid can be derived from a Boswellia serrata extract, and the 3-O-acetyl-11-keto-beta-boswellic acid can be derived from a Boswellia serrata extract. The composition may be formulated for oral administration to a mammalian or avian subject. Methods are provided for treating, repairing, or reducing connective tissue damage caused by one or more inflammatory mediators, and reducing the level of one or more inflammatory mediators in connective tissue, comprising orally administering the composition to a subject in need thereof.

The present application relates to a kind of gout paste set and preparation method thereof, the gout paste includes: paste A and paste B;Paste A is for the umbilical paste of gout remission period;Paste B is used for the paste of the painful joint of attack period;The drug efficacy component of paste A is made of the first traditional Chinese medicine composition comprising the following components: atractylodes, huangjiu, willow bark, yiyiren, wulingzhi, cansha, baizhu, gancao, tougucao, sandalwood, chishao, chuanqiong, dog spine, fuling, zhuling, dilon, chenpi, huoxiang, wangbuliuxing and suhe xiang;The drug efficacy component of paste B is made of the second traditional Chinese medicine composition comprising the following components: jinyinhua, huangbai, yanhuosuo, wulingzhi, cansha, zihuoding, da xueteng, luoshiteng, jixieteng, tougucao, tuobie worm, oyster, laohu, mody, turmeric, danneling, tianzhu huang and ice. The present application effectively reduces the level of patient's blood uric acid, C-reactive protein and cell sedimentation rate and TCM syndrome score, drug safety is high, and recurrence rate is low.

This invention discloses a flavored thick cream and its preparation method: Flavorful protease and lipase are added to butter and / or fermented butter for enzymatic hydrolysis. The hydrolysate is thermally reacted at 85-100℃ for 8-24 hours. The product is centrifuged to obtain oil phase A and aqueous phase B. Oil phase A is emulsified to obtain a first dispersion, and aqueous phase B is emulsified to obtain a second dispersion. The first and second dispersions are mixed to obtain a water-in-oil product. 0.2-0.5 wt% of an oil phase emulsifier is added to the water-in-oil product at 55-65℃ and mixed to obtain a third dispersion. 0.2-0.5 wt% of an aqueous phase emulsifier is added to water to obtain a fourth dispersion. The fourth dispersion is heated to 55-65℃, and the third dispersion is added to the fourth dispersion and mixed. The mixture is then sheared and homogenized to obtain the flavored thick cream. The flavored thick cream prepared by this invention has a rich, pure, natural, and full-bodied aroma and flavor.

The application discloses a synergistic ganoderma lucidum fermentation extract composition and application thereof in skin antioxidation, immunoregulation, anti-aging and anti-wrinkle skin tendering. The composition provided by the application contains the following raw materials in percentage by weight: 0.1-10% of ganoderma lucidum fermentation extract, 0.01-10% of magnesium ascorbyl phosphate, 0.01-5% of glycyrrhiza extract, 0.1-5% of tocopherol, 0.05-3% of boswellic acid extract, 0.01-3% of asiaticoside, 0.01-0.5% of coffee acid, and the balance of solvent. The composition provided by the application realizes three-effect synergism of "immune homeostasis-antioxidation repair-antioxidation" through specific component cooperation, can significantly improve skin inflammation, stabilize the skin immune microenvironment, delay skin aging, and has important application value in the development of skin antioxidation, immunoregulation, anti-aging and anti-wrinkle skin tendering products.

The invention belongs to the technical field of pharmaceutical preparations, and discloses a traditional Chinese medicine ointment with a tissue repair function and a preparation method of the traditional Chinese medicine ointment. The traditional Chinese medicine composition is prepared from, by weight, 3-10 parts of rhizoma coptidis, 3-10 parts of radix scutellariae, 3-10 parts of cortex phellodendri, 10-15 parts of radix angelicae sinensis, 5-10 parts of rhizoma bletillae, 5-10 parts of dragon's blood, 1-5 parts of pearl powder, 5-10 parts of radix arnebiae seu lithospermi, 5-10 parts of raw radix sanguisorbae, 1-5 parts of elephant hide, 10-15 parts of radix angelicae, 10-15 parts of radix salviae miltiorrhizae, 5-10 parts of radix paeoniae rubra, 5-10 parts of frankincense and 5-10 parts of myrrh. 5-10 parts by weight of safflower, 5-10 parts by weight of pseudo-ginseng and 10-15 parts by weight of honeysuckle; the composition further comprises lidocaine, an r-bFGF solution, multivitamins and an oily solvent. Vitamin C and vitamin E are added, so that the anti-oxidation effect of the formula can be further enhanced, collagen synthesis is promoted, and the immunity is enhanced. In combination with an r-bFGF solution, tissue repair and cell growth can be more effectively promoted.

A food composition includes allulose having a concentration of about 43% to about 82% by weight, a cocoa product having a concentration of about 15% to about 50% by weight, and mastic gum or powder having a concentration of about 0.35% to about 2.71% by weight. A food composition also includes allulose having a concentration of about 55% to about 90% by weight, mastic gum or powder having a concentration of about 0.35% to about 5% by weight, and one or more plant-based proteins having a concentration of about 4.7% to about 32.5% by weight. The food compositions may further include secondary sweeteners, polysaccharide hydrocolloids, natural ingredients, plant-based nutrients, plant-based proteins, biominerals, vitamins and / or antioxidants as active ingredients. A confectionary product made with the food compositions and a method of making the food compositions are also disclosed. An allulose-based sweetener and method of making same are also disclosed.

The invention relates to the related technical field of medicated food, in particular to a multifunctional medicated food composition with spleen-tonifying and qi-replenishing effects, which consists of 50g of liquorice, 30g of lemon, 20g of leaf and stem, 50g of lotus, 5g of tartary buckwheat, 5g of realgar, 28g of folium artemisiae argyi, 13g of lotus seed, 7g of frankincense and 13g of astragalus membranaceus. The medicated food has the effects of tonifying spleen and qi, nourishing heart and tranquilizing mind, promoting blood circulation to arrest pain, stimulating menstrual flow and diminishing swelling, enhancing immunity and the like, and can be used for making medicinal liquor soup, pills, health underwear, accessories and other forms. Through scientific compatibility of multiple medicinal materials, the medicated diet synergistically exerts the effects of health preserving medicine, body building, qi and blood circulation promoting and the like, and is suitable for conditioning and health care of multiple sub-health states.

The invention discloses a traditional Chinese medicine composition which comprises the following medicinal materials in terms of 50 preparation units: 60-100 parts of pseudo-ginseng, 60-100 parts of vinegar-processed rhizoma corydalis, 20-60 parts of starfish, 20-60 parts of ground beeltle, 5-15 parts of processed semen strychni, 10-30 parts of safflower, 1-20 parts of vinegar-processed frankincense, 1-20 parts of vinegar-processed myrrh, 1-10 parts of borneol and 0.1-1 part of artificial musk. The invention further discloses a preparation method of a tincture of the traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of medicines for treating acute and chronic falling trauma, neck, shoulder, waist and knee pain or arthralgia. The traditional Chinese medicine composition disclosed by the invention has the effects of relaxing muscles and tendons, promoting blood circulation, dredging collaterals, dissipating blood stasis, diminishing swelling and relieving pain. Pharmacodynamic studies show that the traditional Chinese medicine composition disclosed by the invention takes effect quickly and has a good curative effect when being used for treating symptoms such as traumatic injuries, blood stasis swelling and swelling and red and swollen injuries. The traditional Chinese medicine composition disclosed by the invention effectively relieves the injury condition of a tested animal, and is free of irritation and sensitization to the tested animal in a skin medication toxicity test.

The invention discloses a pharmaceutical composition for treating osteoarthritis as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing selenized epigallocatechin gallate; the preparation method comprises the following steps: preparing a 3-acetyl-11-ketone-beta-masticinic acid phospholipid complex; mixing a sodium alginate solution with the two active components, and adding a CaCl2 cross-linking accelerant to form a medicine carrying solution; preparing sodium alginate-chitosan core-shell drug-loaded microspheres by adopting a coaxial electrostatic spraying technology; modifying the surface of the microsphere by using arginine-glycine-aspartic acid peptide; and curing by CaCl2, and freeze-drying to obtain a final product. The drug stability is remarkably improved through selenylation modification and phospholipid complex technologies, long-acting slow release of the drug is achieved through core-shell microspheres constructed through coaxial electrostatic spraying, and cartilage targeting is enhanced by combining RGD peptide modification. The pharmaceutical composition has excellent anti-inflammatory and cartilage protection effects, is suitable for preparing articular cavity injection preparations, and provides a new solution for osteoarthritis treatment.

The invention relates to the field of cardiovascular disease treatment, in particular to a traditional Chinese medicine composition for improving heart health and a preparation method thereof. The traditional Chinese medicine composition is characterized by comprising twenty traditional Chinese medicines including 5 to 20g of radix salviae miltiorrhizae, 5 to 15g of flos carthami, 5 to 15g of radix paeoniae rubra, 5 to 15g of frankincense, 5 to 15g of myrrh, 5 to 15g of radix notoginseng, 3 to 10g of clove, 5 to 15g of radix aucklandiae, 3 to 10g of agilawood, 5 to 15g of sandalwood, 3 to 10g of storax, 5 to 15g of rhizoma corydalis, 5 to 15g of ligusticum wallichii, 3 to 15g of schisandra chinensis, 3 to 15g of borneol, 500ml of olive oil and the like, and any one or any combination of 5 to 15g of radix codonopsis, 5 to 15g of radix ophiopogonis and 5 to 15g of lignum dalbergiae odoriferae is contained in the formula. The medicine can be quickly absorbed by smelling the medicine, directly enters blood, and is suitable for relieving acute angina pectoris, chest distress and shortness of breath. The health-care tea is an ideal heart health improving product, and is especially suitable for people with coronary heart disease history or high risk of cardiovascular diseases.