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Drug for curing diabetes and nephropathy and its preparing method

A technology for diabetic nephropathy and drugs, which is applied in drug combinations, medical formulas, urinary system diseases, etc., can solve the problems of complex taste, inadaptability, and large dosage, and achieve the effect of protecting kidney function, lowering blood sugar, and definite curative effect

Active Publication Date: 2007-09-26
北京市金药源药物研究院 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its shortcoming is that there are nearly 20 flavors of the formula drug, the taste of the medicine is complex, and the dosage is large.
Its shortcoming is that the herbal medicine composition is a combination of natural medicines, not guided by the theory of traditional Chinese medicine, and not suitable for patients with diabetic nephropathy whose main pathogenesis and syndrome are deficiency of both qi and yin, and stasis of collaterals.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The raw materials were weighed according to the following proportions: 60 parts of astragalus, 20 parts of rehmannia root, 30 parts of Prunella vulgaris, 30 parts of curcuma, 30 parts of ghost arrow feather, 2 parts of panax notoginseng, and 6 parts of rhubarb.

[0063] Preparation method: Take the above seven flavors, extract Astragalus with 50% ethanol twice, the first time 10 times the amount, 2 hours, the second time 8 times the amount, 2 hours, combine the extracts, filter; Rehmannia, Prunella vulgaris, Panax notoginseng Rhubarb was extracted twice with 70% ethanol, the first time was 10 times the amount for 2 hours, the second time was 8 times the amount for 2 hours, the extracts were combined and filtered; the volatile oil was extracted from Zedoary, and the volatile oil was made into β-CD inclusion compound (oil: β-CD: water = 1:6:60, 20°C ultrasonic for 30min), the distilled water liquid was filtered, the filtrate was concentrated to 55-60°C and the relative den...

Embodiment 2

[0067] The raw materials were weighed according to the following proportions: 110 parts of astragalus, 40 parts of rehmannia root, 80 parts of Prunella vulgaris, 80 parts of curcuma, 80 parts of ghost arrow feather, 9 parts of panax notoginseng, and 20 parts of rhubarb.

[0068] Preparation method: Take the above seven flavors, extract Astragalus with 50% ethanol twice, the first time 10 times the amount, 2 hours, the second time 8 times the amount, 2 hours, combine the extracts, filter; Rehmannia, Prunella vulgaris, Panax notoginseng Rhubarb was extracted twice with 70% ethanol, the first time was 10 times the amount for 2 hours, the second time was 8 times the amount for 2 hours, the extracts were combined and filtered; the volatile oil was extracted from Zedoary, and the volatile oil was made into β-CD inclusion compound (oil: β-CD: water = 1:6:60, 20°C ultrasonic for 30min), the distilled water liquid was filtered, the filtrate was concentrated to 55-60°C and the relative d...

Embodiment 3

[0070] The raw materials were weighed according to the following proportions: 84 parts of astragalus, 28 parts of rehmannia glutinosa, 56 parts of Prunella vulgaris, 56 parts of curcuma, 56 parts of ghost arrow feather, 5.6 parts of panax notoginseng, and 16.8 parts of rhubarb.

[0071] Preparation method: Take the above seven flavors, extract Astragalus with 50% ethanol twice, the first time 10 times the amount, 2 hours, the second time 8 times the amount, 2 hours, combine the extracts, filter; Rehmannia, Prunella vulgaris, Panax notoginseng Rhubarb was extracted twice with 70% ethanol, the first time was 10 times the amount for 2 hours, the second time was 8 times the amount for 2 hours, the extracts were combined and filtered; the volatile oil was extracted from Zedoary, and the volatile oil was made into β-CD inclusion compound (oil: β-CD: water = 1:6:60, 20°C ultrasonic for 30min), the distilled water liquid was filtered, the filtrate was concentrated to 55-60°C and the re...

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Abstract

The invention relates to a compound medicament for treating diabetes and nephrosis and process for preparation, wherein the raw materials include Chinese medicinal herbs of astragalus root, dried rehmannia root, selfheal, zedoary, winged euony twigs and right amount of starch gum.

Description

1. Technical field [0001] The invention relates to a drug combination for treating diabetic nephropathy and a preparation method thereof. 2. Background technology [0002] Diabetic nephropathy (DN for short) is one of the systemic microvascular complications of diabetes mellitus (DM for short), and it is also an important cause of death in diabetic patients. It is very common in clinical practice and has a serious prognosis, which is one of the world's medical problems. So far there is no specific and effective control measures. Traditional Chinese medicine has achieved a certain effect in the treatment of diabetic nephropathy, but most of them are decoctions, which are inconvenient to use and should not be taken for a long time. At present, there are also some researches on Chinese patent medicines for treating diabetic nephropathy, such as the capsule for treating diabetic nephropathy with application number 200410020622.7. , leech, cinnamon, grass fruit, toosendan, cum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61K9/20A61K9/48A61P3/10A61P13/12
Inventor 吕仁和
Owner 北京市金药源药物研究院
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