The invention relates to a medicine composition for treating nephropathy. The medicine is prepared from herba epimedii, frangrant ainsliaea herb, polygonum multiflorum, honeysuckle, myrrh, dandelions, oriental wormwood, coptis chinensis, the root of kudzu vines, teasel roots, the root of bidentate achyranthes, radix stemonae, cinnamon, rhizoma atractylodis, radix paeoniae alba, Chinese yams, ginkgo leaves, burdock, rohdea japonica, pepper, acanthopanax, rhizoma acori graminei, golden cypress, rhizoma alismatis and peach kernels. The medicine composition treats both symptoms and root causes of chronic nephrosis in a deficiency and excess mode, the curative effect is definite, the formulation is precise, preparation is easy and convenient, and broad application prospects are achieved.