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Diabetic nephropathy treating traditional Chinese medicine composition

A technology for diabetic nephropathy and a composition, applied in the field of traditional Chinese medicine, can solve the problems of high price of new drugs, and achieve the effects of reducing urinary protein, increasing filtration rate and obvious therapeutic effect.

Active Publication Date: 2018-05-01
北京市房山区中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many new drugs and new uses of old drugs, such as protein glycation end products and oxidative stress inhibitors, direct renin inhibitors and anti-inflammatory drugs with renal protection, immunosuppressant mycophenolate mofetil (MMF) ) application research in DN, etc., but these new drugs are expensive, and there is still a certain distance to the real treatment of DN, and the specific mechanism of its adverse reactions and treatment of DN still needs further in-depth research and discussion

Method used

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  • Diabetic nephropathy treating traditional Chinese medicine composition
  • Diabetic nephropathy treating traditional Chinese medicine composition
  • Diabetic nephropathy treating traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Raw materials: Astragalus 20g, Codonopsis 9g, Angelica 6g, Atractylodes macrocephala 9g, Rehmannia glutinosa 12g, Cornus 9g, Chuanxiong 6g, cooked rhubarb 6g, Citrus aurantium 6g, Salvia miltiorrhiza 10g, Bupleurum 6g;

[0029] Preparation method: Take the above-mentioned raw materials according to the proportion, add water to decoct twice, each time for 1 hour, filter, combine the decoction, concentrate to 200ml, and take it twice in the morning and evening.

Embodiment 2

[0031] Raw materials: Astragalus 18g, Codonopsis 10g, Angelica 5g, Stir-fried Atractylodes macrocephala 10g, Rehmannia glutinosa 11g, Cornus 10g, Chuanxiong 5g, Cooked rhubarb 7g, Citrus aurantium 5g, Salvia miltiorrhiza 12g, Bupleurum 5g;

[0032] Preparation method: Take the raw material drug in proportion, add 60% ethanol to reflux extraction twice, each time for 1 hour, filter, and combine the filtrates to obtain the product.

Embodiment 3

[0034] Raw materials: Astragalus 25g, Codonopsis 8g, Angelica 7g, Stir-fried Atractylodes macrocephala 8g, Rehmannia glutinosa 14g, Cornus 8g, Chuanxiong 7g, cooked rhubarb 5g, Citrus aurantium 7g, Salvia 7g, Bupleurum 7g;

[0035] Preparation method: take the raw material drug in proportion, add 70% ethanol to reflux extraction twice, each time for 1 hour, filter, and combine the filtrates to obtain the product.

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Abstract

The invention relates to a diabetic nephropathy treating traditional Chinese medicine composition, which comprises the following bulk drugs: milkvetch root, codonopsis pilosula, angelica sinensis, atractylodes macrocephala, rehmannia glutinosa, common macrocarpium fruit, ligusticum chuanxiong hort, rheum palmatum l, fructus aurantii, salvia miltiorrhiza, and radix bupleuri.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating diabetic nephropathy, and belongs to the field of traditional Chinese medicines. Background technique [0002] At present, diabetes mellitus (DM) has become one of the diseases that seriously threaten human health. According to the statistics of the International DM Federation, the number of people with DM in the world in 2011 was about 366 million, of which 48% of the growth occurred in China and India. The total number of people suffering from DM in my country has reached 92.4 million, which is much higher than expected. Diabetic nephropathy (DN) is one of the most common and serious microvascular complications of DM. In developed countries in Europe and America, 20%-40% of DM patients are complicated with DN, and finally become the primary cause of dialysis patients. With the increasing number of DM patients ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P3/10A61P13/12
CPCA61K36/232A61K36/233A61K36/236A61K36/284A61K36/344A61K36/40A61K36/481A61K36/537A61K36/708A61K36/752A61K36/804A61K2300/00
Inventor 孔令新王艳云白东海
Owner 北京市房山区中医医院
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