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Traditional Chinese medicine composition for fortifying spleen and nourishing kidney and preparation method and application thereof

A technology for strengthening the spleen and tonifying the kidney and the composition, applied in the field of medicine, can solve the problems of high cost, renal insufficiency, high price, etc., and achieve significant curative effects, improve glomerular filtration rate, and reduce urinary protein.

Inactive Publication Date: 2013-07-03
HUNAN JIUDIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the current clinical treatment includes long-term hemodialysis, peritoneal dialysis and kidney transplantation, these treatment methods are not only expensive, but also have many difficult medical problems
The vast majority of patients in families and units in my country are unable to afford huge losses, especially due to the limited medical conditions in rural areas in my country, most patients are treated conservatively, such as Shenling, ACE inhibitors, etc. for non-dialysis drug treatment, but such treatment It also has the disadvantage of being expensive, and it only relieves symptoms unilaterally, and the elderly are more prone to renal insufficiency

Method used

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  • Traditional Chinese medicine composition for fortifying spleen and nourishing kidney and preparation method and application thereof
  • Traditional Chinese medicine composition for fortifying spleen and nourishing kidney and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Embodiment 1, the preparation of pharmaceutical capsule of the present invention

[0054] Weigh 400g of rhubarb, 250g of Citrus aurantium, 400g of epimedium, 400g of salvia miltiorrhiza, 250g of Chinese yam and 250g of golden cherry, and prepare capsules according to the following method:

[0055] A, rhubarb is pulverized into coarse powder, and 8 times of 75% ethanol is added to reflux extraction for 3 times, each time for 1.5 hours, let cool, filter, combine the filtrates, and reclaim ethanol;

[0056] B. Decoct the weighed epimedium huojia with 3 times the amount of medicinal materials in water for 1 hour, and collect the volatile oil at the same time, set aside, and collect the medicinal liquid in another device;

[0057] C. Decoct the taken Salvia miltiorrhiza, Citrus aurantii, Chinese yam and Fructus Rosa Fructus with 6 times the amount of medicinal materials, each time for 2 hours respectively, merge the decoction, and filter;

[0058] D. Add the alcohol extract...

Embodiment 2

[0060] Embodiment 2, the preparation of pharmaceutical granules of the present invention

[0061] Weigh 250g rhubarb, 500g citrus aurantium, 250g epimedium, 250g salvia miltiorrhiza, 500g yam and 500g golden cherry, and prepare granules as follows:

[0062] A. Grind rhubarb into coarse powder, add 10 times the amount of 65% ethanol to reflux extraction for 3 times, the first time for 1 hour, the second and third times for 1.5 hours respectively, let cool, filter, combine the filtrates, and recover ethanol;

[0063] B. Add 8 times of water to the weighed epimedium and decoct in an appropriate amount for 2 hours, and collect volatile oil at the same time, set aside, and collect the liquid medicine in another device;

[0064] C. Add 3 times the amount of water to decoct the taken Salvia miltiorrhiza, Citrus aurantii, Chinese yam and Rosa laevigata 2 times, each time for 1 hour respectively, combine the decoctions, and filter;

[0065] D. Add the alcohol extract obtained in step...

Embodiment 3

[0067] Embodiment 3, the preparation of medicament oral liquid of the present invention

[0068] Weigh 450g rhubarb, 75g citrus aurantium, 450g epimedium, 150g salvia miltiorrhiza, 300g yam and 300g golden cherry, and prepare granules as follows:

[0069] A. Grind rhubarb into coarse powder, add 5 times the amount of 65% ethanol to reflux and extract twice, extract for 1 hour each time, let cool, filter, combine the filtrates, and reclaim ethanol;

[0070] B. Add 5 times of water to the weighed epimedium and decoct in an appropriate amount for 1 hour, and collect volatile oil at the same time, set aside, and collect the liquid medicine in another device;

[0071] C. Add 3 times the amount of water to decoct the taken Salvia miltiorrhiza, Citrus aurantii, Chinese yam and Rosa japonica for 2 times, each time for 1 hour respectively, combine the decoctions, and filter;

[0072] D. Add the alcohol extract obtained in step B to the filtrate obtained in steps C and D, then add the ...

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Abstract

The invention relates to the technical field of medicines, provides a traditional Chinese medicine composition for fortifying spleen and nourishing kidney, provides a preparation method for the composition and application thereof in treatment of renal dysfunction. The composition of the present invention is used for the treatment of renal dysfunction, and especially has a good effect on chronic renal failure.

Description

field of invention [0001] The invention belongs to the field of medical technology inventions, and specifically relates to a traditional Chinese medicine composition for invigorating the spleen and tonifying the kidney, its preparation method and its application in the preparation of medicines for treating acute and chronic kidney diseases. The traditional Chinese medicine composition contains rhubarb. Background technique [0002] Renal insufficiency is a serious syndrome caused by the development of various acute and chronic kidney diseases to the advanced stage. It is a common difficult disease in clinical practice. According to statistics from the International Society of Nephrology, the annual incidence of chronic renal failure (CRF) in natural populations is 98-198 / 1 million. According to the survey of 2 million urban population in my country, 568 people / 1 million have end-stage renal failure. Although the current clinical treatment includes long-term hemodialysis, pe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P13/12
Inventor 朱志宏卜振军杨静
Owner HUNAN JIUDIAN PHARMA
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