Capsule preparation for treating nephritis associated with hepatitis B and preparation method thereof

A technology of hepatitis B and capsules, which is applied in the field of traditional Chinese medicine preparations, can solve the problem of no specific therapeutic effect on hepatitis B-related nephritis, achieve the effects of inhibiting the replication of hepatitis B virus, improving kidney function, and reducing urinary protein

Inactive Publication Date: 2011-01-05
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the problem that the existing medicines have no specific therapeutic effect on hepatitis B-associated nephritis, and discloses a capsule for treating hepatitis B-associated nephritis

Method used

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  • Capsule preparation for treating nephritis associated with hepatitis B and preparation method thereof
  • Capsule preparation for treating nephritis associated with hepatitis B and preparation method thereof
  • Capsule preparation for treating nephritis associated with hepatitis B and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: Preparation of Active Ingredients for Capsules

[0027] Weigh 800g of rhubarb and 400g of licorice; soak the rhubarb and licorice in water, then decoct twice with a slow fire, combine the decoction, let stand for 2 hours, filter and dry at 70°C to obtain the active ingredient of the capsule.

Embodiment 2

[0028] Example 2: Preparation of Active Ingredients for Capsules

[0029] Weigh 1000g of rhubarb and 500g of licorice, add 20 times the amount of water to soak for 30 minutes, boil it, decoct twice, each time simmer for 20 minutes, combine the water decoction, let it stand for 2 hours, filter it with gauze, and dry it at 70°C to get the product Active ingredients in capsules.

Embodiment 3

[0030] Example 3: Preparation of Active Ingredients for Capsules

[0031] The operating process of this embodiment is the same as that of Example 2, except that 1200 g of rhubarb and 600 g of licorice are weighed.

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Abstract

The invention relates to a capsule preparation for treating nephritis associated with hepatitis B and a preparation method thereof, belonging to the technical field of traditional Chinese medical preparations. The capsule preparation comprises an active component and a pharmaceutically acceptable carrier, wherein the active component is prepared from rhubarb and licorice. The preparation method of the capsule preparation comprises the following steps of: decocting the rhubarb and the licorice, mixing the decoctions, standing still, filtering and drying to obtain the active component; and mixing the active component with medical accessories, pelletizing and subpackaging in capsules to obtain the capsule preparation. The invention can restrict the replication of hepatitis B viruses, protect the liver, reduce enzyme, induce diuresis, reduce urinary protein, serum creatinine and urea, improve the renal function of a glomerulus nephritis rat and has the advantages of concurrent treatment of the liver and kidney, simultaneous treatment of the principal and secondary aspects of the diseases and symptomatic treatment.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a capsule for treating hepatitis B-associated nephritis and a preparation method thereof. Background technique [0002] Hepatitis B associated glomerulonephritis (HBV-GN) is a secondary nephropathy after hepatitis B virus (HBV) infection. Deposits in the glomeruli cause immune inflammation. According to the statistics of the World Health Organization, about 30% of the world's population and 10% of my country's population are infected with hepatitis B virus (Hepatitis B virus, HBV). Patients with chronic nephritis will develop renal failure, which is life-threatening. [0003] At present, there is no specific treatment for hepatitis B-related nephritis. Clinically, adrenal cortex hormones and / or immunosuppressants, antiviral drugs, interferon to control proteinuria and other symptomatic treatments are used to alleviate the condition, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61P13/12A61P1/16A61P31/20
Inventor 肖小河赵艳玲山丽梅王伽伯
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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