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Micropills for treating osteoporosis and its preparation technology

A technology for osteoporosis and pellets, which is used in medical preparations containing active ingredients, bone diseases, medical raw materials derived from ferns/filamentous plants, etc. Moisture softening, bad taste, etc

Inactive Publication Date: 2011-01-12
杨义澄
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the problems that the above-mentioned Gushukang granules have a bad taste, and the granules are easy to absorb moisture and soften, agglomerate and mildew, and are not conducive to taking by diabetic and obese patients, the present invention provides a Gushukang pellet and its preparation process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0041] Epimedium 500.4;

[0042] Rehmannia glutinosa 662.4;

[0043] Drynaria 331.2;

[0044] Astragalus 500.4;

[0045] Danshen 331.2;

[0046] Fungus 265.2;

[0047] Cucumber seeds 265.2;

[0048] Starch 135.

[0049] The present embodiment provides the preparation method of Gushukang pellets as follows:

[0050] 1) Grind 265.2g of cucumber seeds into fine powder and set aside;

[0051] 2) Extract 331.2 g of Danshen medicinal material twice with ethanol back flow, add 12 times the amount for the first time, extract for 2 hours, add 6 times the amount for the second time, extract for 1.5 hours, filter, use the dregs for later use, combine the filtrates, and recover ethanol And concentrated to a clear paste with a relative density of 1.30 (60-70°C), set aside;

[0052] 3) Add 500.4g of salvia miltiorrhiza, 500.4g of epimedium, 662.4g of rehmannia root, 331.2...

Embodiment 2

[0067] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0068] Epimedium 100;

[0069] Rehmannia glutinosa 1400;

[0070] drynaria 60;

[0071] Astragalus 1400;

[0072] Danshen 60;

[0073] Fungus 530;

[0074] Cucumber seeds 50.

[0075] The present embodiment provides the preparation method of Gushukang pellets as follows:

[0076] 1) Grind 50g of cucumber seeds into fine powder and set aside;

[0077] 2) Extract 60 g of Salvia miltiorrhiza medicinal material twice with ethanol under reflux, add 10 times the amount for the first time, extract for 2 hours, add 6 times the amount for the second time, extract for 1.5 hours, filter, use the dregs for later use, combine the filtrates, recover the ethanol and Concentrate to a clear paste with a relative density of 1.25 (60-70°C), set aside;

[0078] 3) Add 100g of salvia miltiorrhiza and epimedium, 1400g of rehmannia glutinosa, 60g of rhizoma drynariae, 1400g of astr...

Embodiment 3

[0093] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0094] Epimedium 1000;

[0095] Rehmannia glutinosa 130;

[0096] Drynaria 660;

[0097] Astragalus 130;

[0098] Danshen 660;

[0099] fungus 50;

[0100] Cucumber seeds 530.

[0101] The present embodiment provides the preparation method of Gushukang pellets as follows:

[0102] 1) Grind 530g of cucumber seeds into fine powder and set aside;

[0103]2) Extract 660 g of Danshen medicinal material twice with ethanol under reflux, add 10 times the amount for the first time, extract for 2 hours, add 8 times the amount for the second time, extract for 1.5 hours, filter, use the dregs for later use, combine the filtrates, recover the ethanol and Concentrated to a relative density of 1.1 (60 ~ 70 ℃) clear paste, set aside;

[0104] 3) Add 1000g of salvia miltiorrhiza and epimedium, 130g of rehmannia glutinosa, 660g of rhizoma drynariae, 130g of astragalus, and 50g...

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PUM

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Abstract

The invention relates to a micro-pill preparation and its producing craft, especially the Gushukang micro-pill and its producing craft. The Gushukang micro-pill is produced according to following weight shares: longspur epimedium 100-1000; ripe radix rehmanniae 200-400; drynaria 60-660; astragalus root 130-1400; radix salviae miltiorrhizae 60-660; dried edible fungus 50-530; cucumber-seed 50-530.The invention has a good resolvability, a smart curative effect, a stable medicine releasing, a high bio-availability, a small local thrill, a beautiful pill appearance, a small moisture absorption, and a good feeling for patients, further it is easy to transport, store and carry.

Description

technical field [0001] The invention relates to a pellet preparation and a preparation process thereof, in particular to a Gushukang pellet and a preparation process thereof. Background technique [0002] Gushukang Granules currently sold in the market meet the national standard WS of the State Drug Administration. 3 -019(Z-006)-99(z), has the functions of invigorating kidney and Qi, promoting blood circulation and strengthening bones. It is used for middle-aged and elderly people with osteoporosis caused by deficiency of kidney qi and blood, accompanied by pain in the waist and spine, soreness of the shins and knees, mental fatigue and fatigue. [0003] The formula of Gushukang granules is as follows: Epimedium 417g, Rehmannia glutinosa 552g, Drynaria drynaria 276g, Astragalus 417g, Salvia miltiorrhiza 276g, Fungus 221g, Cucumber seeds 221g. The preparation method of Gushukang granule is as follows: take the above seven flavors, take Salvia miltiorrhiza and extract twice ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K36/53A61K36/481A61K36/42A61K36/296A61K36/11A61K9/16A61P19/10
Inventor 梁起臣杨义澄
Owner 杨义澄
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