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Medicine micropill and its prepn process

A technology of Shenqi Schisandra and Southern Schisandra, which is applied in the field of Shenqi Schisandra pellets and their preparation, can solve the problems of large chemical and mechanical irritations, unsuitable for long-term use, etc., and achieve small local irritation, excellent disintegration and solubility, Neat and beautiful appearance effect

Inactive Publication Date: 2007-12-19
刘建中
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] After the tablet enters the stomach, it will be attached to a certain point on the stomach wall, so the concentration of the drug formed by the tablet at a local point in the stomach is very high, and the chemical stimulation and mechanical stimulation to the stomach are very large, which may cause gastritis, ulcers, etc. disease, it is not suitable for long-term use, especially for some patients with stomach problems and the elderly

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0022] Southern Schisandra 500;

[0023] Codonopsis 200;

[0024] Astragalus 300;

[0025] Fried Suanzaoren 120.

[0026] The preparation method that present embodiment provides Shenqi Schisandra Pellets is as follows:

[0027] 1) powder Codonopsis pilosula and 1 / 3rd of the amount of southern schisandra into fine powder;

[0028] 2) the Radix Astragali of described amount, stir-fried Jujube Seed and the remaining 2 / 3 of described amount of Fructus Schisandra according to the flow extract and the percolation method under the item of extract ("Chinese Pharmacopoeia" 2005 edition one appendix 10), Use 10 times the amount of 45% ethanol, 70% ethanol and 60% ethanol as solvents, soak for 24 hours and percolate, collect the percolation liquid, recycle the ethanol and combine, and concentrate to a relative density of about 1.20 (60°C). clear ointment, spare;

[0029] ...

Embodiment 2

[0035] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0036] Southern Schisandra 600;

[0037] Codonopsis 150;

[0038] Astragalus 400;

[0039] Fried Suanzaoren 60.

[0040] The preparation method that present embodiment provides Shenqi Schisandra Pellets is as follows:

[0041] 1) the Codonopsis pilosula of said amount and the southern schisandra powder of 1 / 3 said amount are finely powdered, and set aside;

[0042] 2) with the described amount of Radix Astragali, fried Suanzaoren and remaining Schisandra chinensis extract and the percolation method under the item of extract ("Chinese Pharmacopoeia" 2005 edition one appendix 10), use 45% of 12 times the amount respectively Ethanol, 70% ethanol and 60% ethanol were used as solvents, soaked for 24 hours, then percolated, collected the percolated liquid, recovered the ethanol, combined, concentrated to a clear paste with a relative density of about 1.25 (60°C), and s...

Embodiment 3

[0050] The parts by weight of each component in the formula adopted in the present embodiment are as follows:

[0051] Southern Schisandra 500;

[0052] Codonopsis 150;

[0053] Astragalus 400;

[0054] Fried Suanzaoren 120.

[0055] The preparation method that present embodiment provides Shenqi Schisandra Pellets is as follows:

[0056] 1) the Codonopsis pilosula of said amount and the southern schisandra powder of 1 / 3 said amount are finely powdered, and set aside;

[0057] 2) The Astragalus membranaceus, fried Suanzaoren and the remaining Schisandra chinensis extract and the percolation method under the extract item ("Chinese Pharmacopoeia" 2005 edition one appendix 10) were used respectively with 45% of 8 times the amount Ethanol, 70% ethanol and 60% ethanol are used as solvents, soaked for 24 hours, then percolated, and the percolated liquid is collected, recovered from ethanol, combined, concentrated to a clear paste with a relative density of about 1.30-1.35 (60°C),...

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Abstract

The present invention relates to one kind of medicine micropill and its preparation process. The medicine micropill is prepared with Southern schisandra fruit 500-600 weight portions, Dangshen 150-200 weight portions, astragalus root 300-400 weight portions, fried wild jujube seed 60-120 weight portions, and microcrystalline cellulose 400-600 weight portions. It has diameter smaller than 0.05 mm, good disintegrating and dissolving performance, fast acting, stable medicine release, high bioavailability and other advantages.

Description

technical field [0001] The invention relates to a Shenqi Schisandra pellet and a preparation process thereof. Background technique [0002] The currently marketed Shenqi Wuweizi Tablets are the varieties recorded in the 2005 edition of the "Chinese Pharmacopoeia". Dreams, forgetfulness, palpitations, shortness of breath, spontaneous sweating and other symptoms. [0003] The formula of Shenqi Schisandra Tablets is as follows: Southern Schisandra 180g, Codonopsis 60g, Astragalus 120g, and fried Suanzaoren 30g. The preparation method of Shenqi Schisandra sheet is as follows: above four flavors, Codonopsis pilosula and Southern Schisandra 60g are ground into fine powder; Radix Astragali, stir-fried Suanzaoren and remaining Southern Schisandra according to flow extract and percolation hair (appendix 10) under the extract item respectively Use 45% ethanol, 70% ethanol, and 60% ethanol as solvents, soak for 24 hours, then carry out percolation, collect the percolation liquid, rec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K9/16A61P1/14A61P25/20
Inventor 刘建中梁起臣
Owner 刘建中
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