Medication for treating bronchitis

A bronchitis and drug technology, applied in the field of drugs for the treatment of bronchitis, can solve the problems of chronic bronchitis recurrence and pathogenic bacteria recurrence, and achieve the effects of wide distribution in the body and good oral absorption.

Inactive Publication Date: 2007-12-26
沈福水
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The second is that influenza virus infection and respiratory infection lead to the resurgence of residual pathogenic bacteria stored in the bronchi, which leads to the recurrence of chronic bronchitis
The third is the resurgence of residual mycoplasma, chlamydia and pathogenic bacteria in the bronchus, leading to the recurrence of chronic bronchitis

Method used

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  • Medication for treating bronchitis
  • Medication for treating bronchitis
  • Medication for treating bronchitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Tablets are formulated with a total weight of 0.5 g. Includes azithromycin, amantadine hydrochloride, microcrystalline cellulose as prescribed by the Pharmacopoeia, monohydroxypropyl cellulose, magnesium stearate, povidone, and sodium lauryl sulfate.

[0032] The pharmacopoeia of the dispersible tablet allows 0.5g±5%, the total weight is 0.475-0.525g, which is actually 97.17-101.96%=0.48585-0.5098g. The heavy metal content shall not exceed 10 parts per million. Its preparation method is identical with traditional tablet, and following table is the composition of each embodiment of tablet:

[0033] total weight

[0034] Capsules:

[0035] The Pharmacopoeia stipulates that the allowable error of the 0.4g capsule is ±7.5%, that is, 0.4±0.75%, that is, 0.37-0.43 grams.

[0036] Azithromycin accounts for 61-63.39%, that is, 0.2257-0.2725 grams.

[0037] Amantadine hydrochloride accounts for 24.5%-25.58%, that is, 0.09065-0.109994 grams.

[0038] Microcrystall...

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Abstract

The present invention relates to a medicine for effectively curing bronchitis. Said medicine is made up by using azithromycin as first active component, amantadine hydrochloride as second active component and one kind or several kinds of medicinal inactive components through a certain preparation process. The weight ratio of first active component and second active component is 2.5-25:1 and the described inactive components are diluting agent, disintegrating agent, wetting agent and surfactant, etc.

Description

technical field [0001] The invention relates to a medicine for treating bronchitis. Background technique [0002] my country's chronic bronchitis obstructive emphysema disease accounts for about 3% of the total adult population, and the death rate ranks fourth. Since my country is a country with a high proportion of people smoking and a large population base, chronic bronchitis obstructs There are more patients with emphysema, so it has a great impact on the loss of labor force and the decline of people's quality of life. The burden on families and society is heavy, and the medical expenses are relatively high. At present, chronic bronchitis is difficult to cure medically. Repeated attacks of chronic bronchitis will lead to chronic obstructive emphysema becoming more and more serious, and finally lead to cor pulmonale, heart failure and loss of labor force, quality of life and self-care difficulties and death. The reasons for recurrent outbreaks are: the first is that influe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7052A61P11/00A61K31/13
Inventor 沈福水
Owner 沈福水
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