New use of leuprorelin acetate in delaying senility and preventing climacteric syndrome

A leuprolide acetate, aging technology, applied in the directions of medical preparations, drug combinations, peptide/protein components containing active ingredients, etc., to improve E2 level, reduce sugar water consumption, and regulate hypothalamus-pituitary-gonad endocrine Effects of axis functions

Active Publication Date: 2008-01-09
北京博恩特药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report about leuprolide acetate being used for delaying ovarian functio

Method used

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  • New use of leuprorelin acetate in delaying senility and preventing climacteric syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Leuprolide acetate is made into microemulsion injection by conventional technology, one 1ml contains 4 micrograms of leuprolide acetate per milliliter, and is used for the treatment of menopausal syndrome. This injection is injected for adults, once a month, 1 bottle each time, 1 ml each time.

Embodiment 2

[0047] Leuprolide acetate is made into microemulsion injection by conventional technology, one bottle of 1 ml contains 20 micrograms of leuprolide acetate per ml, and is used for the treatment of menopausal syndrome; this injection is injected once a month for adults, one bottle at a time , one 1ml.

Embodiment 3

[0049] Leuprolide acetate is made into microemulsion injection by conventional technology, one 1 ml, each ml contains 120 micrograms of leuprolide acetate for the treatment of menopausal syndrome; this injection is injected once a month for adults, 1 stick at a time, One 1ml.

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PUM

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Abstract

The invention is concerned with a kind of new purpose of Leuprorelin Acetate to stave procreation function and prevent and cure climacteric syndrome. Leuprorelin Acetate is a kind of activated ramification for hypothalamus gonadotropin releasing hormone (GnRH), and micro amount of Leuprorelin Acetate replaces function of effete hypothalamus with age to active and renew the endocrine function of gonad to pituitary-ovary or testicle and avoid the decline of ovary or testicle with age. It renews endocrine balance of hypothalamus- pituitary-gonad and staves the senescence of ovarian function and prevent climacteric syndrome.

Description

technical field [0001] The invention relates to a new application of medicine, in particular to a new pharmaceutical application of leuprorelin acetate. Background technique [0002] Leuprolide acetate is a highly active derivative of hypothalamic gonadotropin-releasing hormone (LH-RH). testis) to synthesize and secrete sex hormones. Long-term large-scale use can positively inhibit the synthesis and secretion of testicular or ovarian sex hormones, and is often used clinically for sex hormone-dependent tumors and other diseases such as prostate cancer, breast cancer, uterine fibroids, endometriosis, and precocious puberty in children Treatment. There is no report about leuprolide acetate being used for delaying ovarian function aging and preventing and treating menopausal syndrome before the present invention. Contents of the invention [0003] The purpose of the invention is to disclose the new pharmaceutical application of leuprolide acetate in delaying ovarian functio...

Claims

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Application Information

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IPC IPC(8): A61K38/08A61K9/19A61K9/10A61P15/12
Inventor 冯前进冯玛丽梁卫郭光明崔晓星周晓庆
Owner 北京博恩特药业有限公司
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