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Method for preparing 'rupikang' capsule

A technology of Rupikang and capsules, which is applied in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of large dosage, limited use range, large-scale production, and low bioavailability

Active Publication Date: 2008-04-30
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the disadvantages of large dosage, poor taste, difficulty in swallowing and low bioavailability of pills and granules, the scope of use and large-scale production of the drug are greatly limited.

Method used

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  • Method for preparing 'rupikang' capsule
  • Method for preparing 'rupikang' capsule
  • Method for preparing 'rupikang' capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] Prescription: Danshen 180g, β-cyclodextrin 45g;

[0080] 500g Prunella vulgaris, 400g orange leaves, 220g safflower, 160g turmeric, 300g saponins, 280g Cyperus cyperi, 240g earthworm;

[0081] Preparation:

[0082] ① Soak the salvia miltiorrhiza and β-cyclodextrin in water for 30 minutes, then decoct twice, the first time for 0.5 hours, the second time for 1 hour, filter, and the filtrate is concentrated into a thick paste with a relative density of 1.30 measured at 60°C, ready for use;

[0083] ② Decoct Prunella vulgaris, orange leaves, salvia miltiorrhiza, safflower, turmeric, saponins, Cyperus cyperi, and earthworm with water for 2 times, the first time for 1 hour, and the second time for 3 hours, combine the decoction, filter, The filtrate is concentrated into a thick paste with a relative density of 1.10 measured at 60°C; the amount of water added is 6 and 8 times the total weight of Prunella vulgaris, orange leaves, salvia miltiorrhiza, safflower, turmeric, sapon...

Embodiment 2

[0086] Prescription: Danshen 280g, β-cyclodextrin 60g;

[0087] Prunella vulgaris 350g, orange leaves 600g, safflower 150g, turmeric 250g, saponins 180g, Cyperus cyperi 240g, earthworm 100g;

[0088] Preparation:

[0089] ① Soak Salvia miltiorrhiza and β-cyclodextrin in water for 45 minutes, then decoct 3 times, for 1.5 hours for the first time, 1 hour for the second time, 0.5 hours for the third time, filter, and concentrate the filtrate to a thick liquid with a relative density of 1.10 measured at 60°C. ointment, ready to use;

[0090] ② Decoct Prunella vulgaris, orange leaves, salvia miltiorrhiza, safflower, turmeric, saponins, Cyperus cyperi, and earthworm with water twice, for 2 hours for the first time, and 1.5 hours for the second time, combine the decoctions, filter, The filtrate is concentrated into a thick paste with a relative density of 1.20 measured at 60°C; the amount of water added is 10 and 6 times the total weight of Prunella vulgaris, orange leaves, salvia ...

Embodiment 3

[0093] Prescription: Danshen 150g, β-cyclodextrin 35g;

[0094] Prunella vulgaris 700g, orange leaves 380g, safflower 280g, turmeric 100g, saponins 240g, Cyperus cyperi 150g, earthworm 300g;

[0095] Preparation:

[0096] ① Soak the salvia miltiorrhiza and β-cyclodextrin in water for 60 minutes, then decoct twice, the first time for 1 hour, the second time for 1.5 hours, filter, and the filtrate is concentrated into a thick paste with a relative density of 1.40 measured at 60°C, ready for use;

[0097] ② Decoct Prunella vulgaris, orange leaves, salvia miltiorrhiza, safflower, turmeric, saponins, Cyperus cyperi, and earthworm with water for 3 times, the first time for 1 hour, the second time for 3 hours, the third time for 2 hours, and combine Decoction, filtration, the filtrate is concentrated into a thick paste with a relative density of 1.40 measured at 60°C; the amount of water added is the total weight of Prunella vulgaris, orange leaves, salvia miltiorrhiza, safflower, t...

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Abstract

The invention discloses a process for preparing a capsule for treating milk addiction. After being soaked with water for 15 to 60 minutes, radix salviae miltiorrhizae and cyclodextrins are decocted, and filtering liquid is condensed into thick paste. Self-heal, folium citri reticulatae, radix salviae miltiorrhizae, safflower, radix curcumae, spina gleditsae, nutgrass galingale rhizome and earthworm are decocted with water, and the filtering liquid is condensed into the thick paste. The two thick pastes are combined and are crushed into powder after being dried by reducing pressure, and then the powder is homogeneously mixed with disintegrants to palletize with ethanol, the capsule is made after the palletized pellets are screened, dried, combined into an integral pellet and are filled intothe capsules. The capsule for treating the milk addiction provided by the invention has the advantages of simple technique, low cost, high bioavailability, good mouth feel, and convenient taking, andthe invention is capable of being used for treating symptoms such as breast tenderness, breast bilging pain and the like caused by liver-Qi depression and qi stagnation and blood stasis.

Description

technical field [0001] The present invention relates to a preparation method of Rupikang Capsules for treating breast diseases, in particular to a preparation method of Rupikang Capsules for treating liver qi stagnation, mammary gland hyperplasia and breast pain caused by qi stagnation and blood stasis . Background technique [0002] Breast disease is a common disease and frequently-occurring disease in women. The incidence of breast disease has reached 32.24% of women of childbearing age, and the incidence of mammary gland hyperplasia is 30.4%, accounting for more than 80% of all breast diseases. Preparations are used to treat such diseases, but such drugs have large side effects on the human body, slow curative effect, and poor drug resistance of patients. [0003] The application number is 03124458.0, the invention name is: Rupikang Pill and its preparation method, the application number is 03118940.7, the invention name is: Rupikang Granule and its preparation method. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61K9/16A61P15/14A61K35/64A61K35/62
Inventor 杨文龙
Owner 杨文龙
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