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Medicine composition for curing arrhythmia and preparation method thereof

A technology of arrhythmia and composition, which is applied in the field of traditional Chinese medicine preparations for treating arrhythmia and its preparation, and can solve the problems of insufficient nourishing qi and tonifying yang, unsatisfactory effects, etc.

Active Publication Date: 2008-05-21
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On November 16, 2000, the Chinese Patent Gazette published a patent application titled "Traditional Chinese Medicine Composition for Treating Sick Sinus Syndrome" with publication number 1354004. Made from cistanche, cassia twig, nard pine, asarum, ephedra, salvia miltiorrhiza, and chuanxiong, but the effect of nourishing qi and nourishing yang is insufficient, and the effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Example 1: 100g of red ginseng, 250g of epimedium, 750g of psoralen, 250g of medlar, 250g of ephedra, 375g of salvia miltiorrhiza, 250g of leech, 50g of asarum; add 6 times of water to asarum, extract by steam distillation for 6 hours, filter , collect the volatile oil, and collect the filtrate in another device; the volatile oil is added with an appropriate amount of polysorbate-80 to dissolve it for later use; the red ginseng is extracted three times with 75% ethanol under reflux, the first time is 1.5 hours, and the remaining time is 1 hour, filter and combine the filtrates, Recover ethanol, add water to about 100ml, refrigerate for 72 hours, filter, and use the filtrate for later use. Add 10 times of water to the other 6 herbs such as Epimedium, decoct three times, 1 hour each time, combine the decoction, filter, combine the filtrate and the distilled filtrate, filter, and concentrate the filtrate under reduced pressure (40°C) to a relative density of 1.09, add etha...

Embodiment 2

[0084] Red ginseng 50g, epimedium 375g, psoralen 375g, medlar 375g, ephedra 125g, salvia miltiorrhiza 200g, leech 375g, asarum 25g; Asarum was added 5 times of water, extracted by steam distillation for 8 hours, filtered, collected volatile oil, Collect the filtrate in another device; add 2 times of β-cyclodextrin to the volatile oil, add 3 times of water, grind for 30 minutes, dry at low temperature (40°C), grind into a fine powder, and sieve for later use; Red ginseng is extracted three times with 55% ethanol under reflux, each After 1 hour, filter, combine the filtrates, and recover ethanol. Add 8 times of water to the other 6 ingredients such as Epimedium, decoct three times, 1 hour each time, combine the decoction with the above two filtrates, filter, and concentrate the filtrate under reduced pressure at 30°C to a clear paste with a relative density of 1.20, add the above β-cyclodextrin inclusion complex, packed into capsules, ready to use.

Embodiment 3

[0086] Red ginseng 150g, epimedium 125g, psoralen 1125g, medlar 125g, ephedra 375g, salvia miltiorrhiza 550g, leech 125g;

[0087]Add Asarum 10 times water, extract by steam distillation for 4 hours, filter, collect the volatile oil, and collect the filtrate in another device; add β-cyclodextrin 6 times the volatile oil, add 1 time water, grind for 30 minutes, dry at 60°C, and grind into fine powder powder, sieved for later use; red ginseng was refluxed with 90% ethanol and extracted three times, each time for 2 hours, filtered, the filtrate was combined, and ethanol was recovered; the remaining 6 ingredients such as epimedium were added with 12 times of water, decocted three times, each time for 2 hours, The decoction is combined with the above two filtrates, filtered, and the filtrate is concentrated under reduced pressure to a clear paste with a relative density of 1.10 at 60°C. Mix the starch, take out 15-20% mixed powder for later use; add 5-10% polyvinylpyrrolidone absol...

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PUM

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Abstract

The invention relates to a drug combination which cures arrhythmia and a production method. The drug combination is produced by red ginseng, epimedium, fructus psoraleae (stir-frying with salt-water), medlar, ma-huang, asarum, salvia miltiorrhiza and bloodsucker. The granule types comprise grain granule, hard capsule granule, soft capsule granule, troche, drop pill, pill and oral liquid preparation. The invention aims at providing a drug curing the arrhythmia, not only has accurate curative effects, but also better improves clinic symptoms, shortens the treatment period and prevents recrudescence.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating arrhythmia and a preparation method thereof. Background technique [0002] Sick sinus syndrome (sick sinus for short) and sinus bradycardia (sinus bradycardia for short) are common arrhythmia diseases. Traditional Chinese medicine believes that sick sinus and sinus depression are caused by deficiency of heart and kidney yang and cold coagulation of blood vessels. On November 16, 2000, the Chinese Patent Gazette published a patent application titled "Traditional Chinese Medicine Composition for Treating Sick Sinus Syndrome" with publication number 1354004. Cistanche, Guizhi, Gansong, Asarum, Ephedra, Salvia, Chuanxiong, but the effect is not satisfactory due to the deficiency of Qi and Yang. Contents of the invention [0003] The purpose of the present invention is to provide a new traditional Chinese medicine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P9/06A61K35/62
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA
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