Chinese patent drug nectar disinfection capsule for treating cold reducing-fever and preparing process thereof

Abstract

The invention discloses a Chinese traditional medicine Ganlu Jieduwan (tablet) for treating cold and clearing heat and the preparation method. The invention which contains 11 drugs such as Radix Scutellariae, pulvis talci, Rhizoma Acori Graminei and Rhizoma Belamcandae is the improved preparation on the basis of the original Ganlu disinfecting pill and is also the extractive refined and extracted according to the recipe quantity. 100 parts of the extractive and 0.2-0.5 parts of magnesium stearate are mixed and prepared into tablets, wherein the extractive is prepared by water extraction, alcohol extraction and alcohol-water mixed extraction while the content of the effective ingredient Baicalin is not lower than 9.0 per cent. The Ganlu disinfecting capsule (tablet) of the invention is characterized by small dose, quick degradation and high bioavailability; thereby the invention is applicable for people in different ages.

Description

[0001] Relevant instructions [0002] This application is a divisional application of the application number 200419919465.8 filed on June 2, 2004. technical field [0003] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a Chinese patent medicine Ganlu Xiaoxiao Capsule (tablet) for treating colds and clearing away heat and a preparation process thereof. Background technique [0004] In ancient times, Chinese patent medicines for treating colds were mostly pills or powders, but they were inconvenient to take because they were prone to mildew and deterioration in summer, and the dosage was large. In modern times, some ancient prescriptions or classic prescriptions are changed into tablets, capsules or granules. For example, Ganlu Xiaoxiao Pill is an ancient classic prescription, and its dosage form is water pill, (see the Ministry of Health of the People's Republic of China Drug Standards, Volume 9, page 54) mainly used for treat...

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Problems solved by technology

For example, Ganlu Xiaoxiao Wan is an ancient classic prescription, and its dosage form is a water pill. (For details, see the Ministry of Health of the People's Republic of China, Volume 9, Page 54 of Drug Standards). Obvious toxic and side effects, but due to the limitations of the dosage form and dosage, the market share has been small, far from meeting the needs of the majority of cold and fever patients

[0005] At present, Ganlu Xiaodu pills mainly have the following problems: (1). The long dissolution time generally takes 50 minutes, resulting in slow oral absorption and reduced bioavailability, which is not conducive to the efficacy of the drug; (2). The dosage is relatively large , taking about 86-129 pills (equivalent to 6-9 grams of crude drug) each time, causing inconvenience to patients, especially the elderly; (3). Since the preparation process of Ganlu Xiaoxiao Pills is to crush the prescription medicinal materials into powder It is directly formed into pan pills, so the drug content is low, and there is no quality standard control at present, and it is difficult to meet the hygiene inspection standards, etc.

In short, the solubility, dissolution rate, bioavailability and active ingredient content control of Ganlu disinfection pills need to be further improved.

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