Mass spectrum model used for detecting liver cancer characteristic protein and preparation method thereof

A characteristic protein and mass spectrometry model technology, which is applied in the field of malignant tumor liver cancer detection, achieves high sensitivity and specificity, reasonable and feasible design, and improves survival rate and quality of life
CN101403740AInactive Publication Date: 2009-04-08BIOYONG TECH

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BIOYONG TECH
Publication Date
2009-04-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a mass spectrometry model used for detecting hepatocellular carcinoma serum characteristic protein, and a preparation method used for the mass spectrometry model. The method uses a plurality of characteristic protein combinations which are different in hepatocellular carcinoma patients and normal people to detects the hepatocellular carcinoma serum, adopts a method combining the traditional statistics with the modern biological informatics to process data, measures the protein combination spectrum spectrogram of serum samples of hepatocellular carcinoma patients and normal people by utilizing a mass spectrograph, and screens out the tumor markers of five corresponding hepatocellular carcinoma characteristic proteins, thus preparing the mass spectrometry model used for detecting the hepatocellular carcinoma serum characteristic proteins and provides foundation and resource for finding newer and more ideal tumor markers.
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Description

technical field

[0001] The invention relates to the field of malignant tumor liver cancer detection, and is a brand-new non-invasive detection method for early discovery and detection of liver cancer in vitro, and the sensitivity and specificity both reach 100%. Background technique

[0002] Primary liver cancer (hereinafter referred to as liver cancer) is one of the high incidence cancers in my country. Not only the incidence rate is very high in the southeast coastal areas, but also the incidence rate in the northwest area is not low. The reason is roughly related to the widespread prevalence of hepatitis B in my country. Now hepatitis B vaccination has been gradually promoted in our country. According to preliminary reports, the incidence of liver cancer has been significantly reduced in adolescents who have received hepatitis B vaccination. However, the high incidence of liver cancer is in the middle-aged and elderly people, so it will take time for the incidence of l...

Claims

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