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Compound fubennikao injection

A technology of compound florfenicol and florfenicol is applied in the directions of pharmaceutical formulations, non-active medical preparations, digestive system, etc., and can solve the problems of reducing curative effect, excessive drug residues, etc., so as to improve curative effect, reduce discomfort, The effect of increasing weight gain

Inactive Publication Date: 2009-05-06
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the long-term repeated use of the above-mentioned drugs alone has caused the pathogenic microorganisms to develop resistance to the drugs, reducing the curative effect, and excessive drug residues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] a. Weigh 1.5kg of Florfenicol and put it into 2.5L of dimethylformamide, stir for 10-25min until clear;

[0019] b. Weigh 0.2kg of doxofylline and put it into 3L of propylene glycol, heat to 50-60°C and stir for 10-25min until clear;

[0020] c. Combine the solutions prepared in a and b, then add propylene glycol to 10L, stir evenly, keep for 15-20min, and make a compound florfenicol injection after the liquid is clear.

Embodiment 2

[0022] a. Put 1.2kg of florfenicol into 2.2L of dimethylformamide, stir for 10-25min until clear;

[0023] b. Take 3L of propylene glycol, add 0.15kg of doxofylline, heat to 50-60°C and stir to dissolve;

[0024] c. Combine the solutions prepared in a and b, then add propylene glycol to 10L, stir evenly, keep for 15-20min, and prepare a compound florfenicol injection after the liquid medicine is clarified.

Embodiment 3

[0026] a. Put 1.1kg of florfenicol into 2L of dimethylformamide, stir for 10-25min until clear;

[0027] b. Take 3L of propylene glycol, add 0.12kg of doxofylline, heat to 50-60°C and stir to dissolve;

[0028] c. Combine the solutions prepared in a and b, then add propylene glycol to 10L, stir evenly, keep for 15-20min, and prepare a compound florfenicol injection after the liquid medicine is clarified.

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PUM

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Abstract

The invention discloses a compound florfenicol injection for curing porcine mycoplasmas infection, which belongs to a medical preparation containing effective components, or an anti-infection animal medicament. Every 100L of injection is prepared by the following materials: 5 to 20kg of florfenicol, 10 to 30L of dimethylformamide, 0.5 to 5kg of doxofylline and the rest is propanediol. The invention adopts a compound preparation of florfenicol and doxofylline, which is highly effective to the mycoplasmal pneumonia of swine, reduces the medicament use times, treats both principal and secondary aspects of diseases and eases the stress response of the body of an affected animal. The injection for curing porcine mycoplasmas infection can be broadly applied to the porcine mycoplasmas diseases, relieve the clinical symptoms caused by the infection of the porcine mycoplasmas and increase the weight of the pig.

Description

technical field [0001] The invention relates to a pharmaceutical preparation containing organic active ingredients, or an anti-infection veterinary medicine, in particular to a compound florfenicol injection for veterinary use. Background technique [0002] Mycoplasma pneumonia is a common disease in pigs, which can cause typical respiratory symptoms such as coughing and wheezing in pigs. Mycoplasma pneumonia in swine is mainly caused by mycoplasma, also known as swine panting disease. It is an acute fulminant epidemic in new epidemic areas, and chronic or recessive outbreaks are more common in old epidemic areas. Various stress factors can promote the occurrence or aggravation of swine mycoplasma pneumonia, and it is widespread. In recent years, macrolides or quinolones are often used as the drug of choice for this disease. [0003] Florfenicol (Florfenicol), also known as fluthionase or chloramphenicol fluoride, is commonly used clinically and belongs to the amide alcoho...

Claims

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Application Information

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IPC IPC(8): A61K31/522A61K9/08A61K47/16A61K47/10A61P31/00A61P11/00A61P1/00A61P15/00A61K31/165
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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