Disinfectant for animals and preparation method thereof

Abstract

The invention discloses a disinfectant for animals and a preparation method thereof, belonging to the field of medicines for veterinary use. The disinfectant for animals takes glutaric dialdehyde, single-chain quaternary ammonium salt and double-chain quaternary ammonium salt as active ingredients. The preparation method comprises the following steps: 1) adding glutaric dialdehyde, alcohol and surfactant to a container to stir uniformly and place statically; 2) adding single-chain quaternary ammonium salt and double-chain quaternary ammonium salt; 3) using a part phosphoric acid buffer solution to dissolve the chelating agent and oxidant completely and mixing with the above ingredient; and 4) continuously adding phosphoric acid buffer solution to the formulation amount to obtain a disinfectant stock solution with pH value of 2.5-4.0. The invention has low toxicity, low irritation, small smell, small corrosiveness, high efficiency of disinfection and side disinfecting spectrum. The liquid disinfectant with wide bactericidal spectrum and some washing efficiency is specifically suitable for daily disinfection of colony house, and is suitable for largely popularizing and using.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a compound veterinary disinfectant containing glutaraldehyde and single- and double-chain quaternary ammonium salts suitable for disinfection of livestock and poultry, livestock houses and livestock and a preparation method thereof. Background technique [0002] With the rapid development of intensive breeding industry, it has become an important measure to prevent and control the epidemic of livestock and poultry infectious diseases by using disinfectants to disinfect livestock and poultry and their surroundings to kill pathogens and cut off the transmission route. However, the commonly used disinfectants such as bleaching powder, sodium hypochlorite, peroxide, phenols, formaldehyde, etc. have some common shortcomings, such as poor stability, strong corrosion, strong irritation, etc., and some are also harmful to the human body. It even has carcinogenic effects. [0003] Glutaraldehyde is a br...

AI Technical Summary

Problems solved by technology

However, the biggest defect of quaternary ammonium cationic surfactants is their narrow antibacterial spectrum (effective against viruses, bacteria, and fungi, but ineffective against mycoplasma and spores), which greatly limits their clinical use in veterinary medicine.

Although the combined use of single and double-chain quaternary ammonium salts can also improve the disinfection effect, as in U.S. Patent No. 4,464,398, single-chain quaternary ammonium salts are used in conjunction with single-chain quaternary ammonium salts, although compared with using a single quaternary ammonium salt disinfectant However, due to the narrow bactericidal spectrum of quaternary ammonium salts, it cannot kill mycoplasma and spores, so it cannot be used as a broad-spectrum disinfectant

Another U.S. patent, US5322856, mentions the combined use of glutaraldehyde and double-chain quaternary ammonium salts, which expands the bactericidal spectrum, but only uses a single variety of quaternary ammonium salts to make it vulnerable to the action of organic matter

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