Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Valsartan liposome, preparation method thereof and medicinal composition containing same

A technology for valsartan resin and a composition, which is applied in the field of medicine, can solve the problems of large size of the pharmaceutical composition, unsuitable for varieties with high main drug content, and low main drug content, etc., and achieves stable product quality and improved biological Availability and efficacy of the drug show fast effects

Inactive Publication Date: 2010-08-25
王丽燕
View PDF6 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prepared liposome also has higher auxiliary material content and less main drug content; the external size of the pharmaceutical composition made from liposomes is too large, and is also not suitable for varieties with higher main drug content.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Valsartan liposome, preparation method thereof and medicinal composition containing same
  • Valsartan liposome, preparation method thereof and medicinal composition containing same
  • Valsartan liposome, preparation method thereof and medicinal composition containing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

Embodiment 2

Embodiment 3

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Concentrationaaaaaaaaaa
Diameteraaaaaaaaaa
Hardnessaaaaaaaaaa
Login to View More

Abstract

The invention relates to valsartan liposome, a preparation method thereof and a medicinal composition containing the same. Active components of the medicinal composition are valsartan and / or amlodipine. The valsartan liposome consists of the valsartan or pharmaceutically acceptable salt thereof and phospholipid, wherein the weight of the phospholipid is 1 to 10 times that of the valsartan or the pharmaceutically acceptable salt thereof; and the medicinal composition prepared by the valsartan liposome not only meets the requirement of Chinese Pharmacopoeia, but also has the advantages of quicker dissolution, quicker drug effect exertion, obviously improved biological utilization compared with conventional valsartan medicinal composition.

Description

A kind of valsartan liposome, its preparation method and its pharmaceutical composition technical field The invention relates to a valsartan liposome, a preparation method thereof and a pharmaceutical composition containing it. The valsartan liposome has a faster dissolution rate and a faster drug effect than ordinary valsartan pharmaceutical compositions. 1. The advantages of significantly improved bioavailability belong to the technical field of medicine. Background technique Due to the development of social economy and the change of people's lifestyle, the prevalence of hypertension in our country shows a continuous growth trend. Hypertension is a common and frequently-occurring disease, and it is also the most important risk factor for cardiovascular and cerebrovascular diseases. There is a continuous positive correlation between blood pressure level and the incidence of cardiovascular disease. The important complications of hypertension, stroke, heart disease and ki...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/127A61K9/20A61K9/48A61K31/41A61K31/4422A61K47/24A61P9/12
Inventor 王丽燕
Owner 王丽燕
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com