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Traditional Chinese medicine composition for treatment of rheumatoid arthritis and preparation method thereof

A composition and arthritis technology, applied in the field of medicine, can solve problems such as no optimization arrangement, insignificant effect, unsatisfactory effect, etc.

Inactive Publication Date: 2010-12-29
上海市长宁区光华中西医结合医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these traditional Chinese medicine compositions have insignificant drug effects, the effect between each component is not obvious, and the effect achieved is not ideal, and in the process of preparing traditional Chinese medicine preparations, the steps of each component are not optimized, and the yield of the preparation not tall

Method used

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  • Traditional Chinese medicine composition for treatment of rheumatoid arthritis and preparation method thereof
  • Traditional Chinese medicine composition for treatment of rheumatoid arthritis and preparation method thereof
  • Traditional Chinese medicine composition for treatment of rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] prescription one

[0023] White Hair Rattan 8g Small Green Grass 8g Double-faced Needle 8g Dandelion 8g

[0024] Smilax 8g Equisetum 10g

[0025] Add a total of six traditional Chinese medicines to the prescription, add water to decoct twice, add 2800ml of water for the first time, decoct for 2 hours, add 2800ml of water for the second time, decoct for 1.5 hours, filter the decoction, combine the filtrates, concentrate under reduced pressure to a relative density of 1.04 (60°C), add 2.5g of sodium benzoate and 0.4g of stevioside, mix well, let stand overnight, take the supernatant, add water to make 1000ml, mix well, fill, and sterilize.

Embodiment 2

[0027] Prescription two

[0028] White Hair Rattan 6g Small Green Grass 6g Double-faced Needle 7g Dandelion 8g

[0029] Smilax 8g Equisetum 8g

[0030] Add a total of six traditional Chinese medicines in prescription two, add water to decoct twice, add 2800ml of water for the first time, decoct for 5 hours, add 2800ml of water for the second time, decoct for 4 hours, filter the decoction, combine the filtrates, and concentrate under reduced pressure until the relative density is 1.04 (60°C), add 2.5g of sodium benzoate and 0.4g of stevioside, mix well, let stand overnight, take the supernatant, add water to make 1000ml, mix well, fill, and sterilize.

Embodiment 3

[0032] Prescription three

[0033] White Hair Rattan 10g Small Green Grass 10g Double-faced Needle 10g Dandelion 9g

[0034] Sarsaparilla 10g Equisetum 12g

[0035] Add 2500ml of water for the first time, decoct for 2 hours, add 2500ml of water for the second time, decoct for 1.5 hours, filter the decoction, combine the filtrates, and concentrate under reduced pressure until the relative density is 1.06 (60°C), add 2.5g of sodium benzoate and 0.4g of stevia, mix well, let it stand overnight, take the supernatant, add water to make 1000ml, mix well, fill it, and sterilize it.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for the treatment of rheumatoid arthritis and a preparation method thereof, and application thereof to preparing medicines for the treatment of wind dampness and rheumatoid arthritis. The traditional Chinese medicine composition according to the invention contains the following components in part by weight: bittersweet herb, all-grass of straightstalk alpine meadowrue, Radix zanthoxyli, dandelion, chinaroot greenbrier, Equisetum hiemale Linne and the like. The traditional Chinese medicine composition according to the invention can be prepared into mixture form, is simpler and cheaper compared with the prior art, and is favorable for transportation and storage. In addition, clinical experiments prove that the traditional Chinese medicine composition according to the invention has obvious therapeutic effect for wind dampness and rheumatoid arthritis.

Description

technical field [0001] The invention belongs to the field of medicine, and more specifically, the invention relates to a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (rheumatoid arthritis, RA) is a systemic chronic autoimmune disease characterized by inflammation of the joint synovium. The pathogenesis of RA is still not very clear. Trenthem first discovered that 50% of RA patients have serum There are autoantibodies against type II collagen (Collagen type II, C II), and based on these findings, an experimental arthritis animal model was first established in 1977. C II exists in large quantities in articular cartilage, and also exists in the retina and vitreous Among them, C II is a protein that is isolated from the immune system, but it can be presented as a self-antigen under certain pathological conditions. Extensive and in-depth research has been carried ou...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P29/00A61P19/04A61P19/02
Inventor 何东仪沈杰姜婷李卓伶倪立青周嘉陵张之澧
Owner 上海市长宁区光华中西医结合医院
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