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Traditional Chinese medicinal composition for curing coronary disease and heart failure and preparation method thereof

A composition and technology for coronary heart disease, which can be used in drug combinations, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problems of long treatment time and unstable arterial plaque, and achieve the effect of promoting angiogenesis

Active Publication Date: 2011-01-26
NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0010] However, the main problems of angiogenesis therapy are safety, causing tumors, instability of arterial plaques, and relatively long treatment time.

Method used

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  • Traditional Chinese medicinal composition for curing coronary disease and heart failure and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh raw materials: Astragalus 9g, Rhodiola 6g, Jiangxiang 15g, Fangji 12g and cinnamon 4.5g, add 10 times the amount of water to the raw materials, heat and reflux for extraction for 2 hours, filter; then add 10 times the amount of of water, heated to reflux for extraction for 1 h, filtered; the residues were discarded, and the two extracts were combined. Concentrate and dry to obtain a dry extract; add appropriate amount of auxiliary materials to obtain granules.

Embodiment 2

[0027] Weigh raw materials: Astragalus 30g, Rhodiola rosea 6g, Jiangxiang 12g, Fangji 12g and cinnamon 3g, process the raw materials into 20 mesh medicinal material powder, add 8 times the amount of water, irradiate with 850W microwave power for 5min, filter, add An appropriate amount of auxiliary materials is used to obtain an oral liquid.

Embodiment 3

[0029] Weigh raw materials: Astragalus 30g, Rhodiola rosea 6g, Jiangxiang 9g, Fangji 12g and cinnamon 4.5g, process the raw materials into 100 mesh medicinal powder, add 6 times the amount of 5% ethanol to soak for 60min, and radiate with 85W microwave power After 60 minutes, filter, take the filtrate, concentrate and dry to obtain a dry extract, and add appropriate amount of auxiliary materials to obtain granules.

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Abstract

The invention discloses a traditional Chinese medicinal composition for curing coronary disease and heart failure, which is prepared from the following raw material medicaments in percentage by weight: 19.35 to 63.16 percent of astragalus membranaceus, 4.65 to 20.34 percent of rhodiola rosea, 14.63 to 46.15 percent of lignum dalbergiae odoriferae, 7.5 to 29.03 percent of stephania tetrandra and 1.64 to 15 percent of cinnamon. The traditional Chinese medicinal composition of the invention can promote angiogenesis. Clinical searches prove that the traditional Chinese medicinal composition has acertain treatment effect on outpatients with the coronary disease and heart failure which are determined as vital energy deficiency and blood stasis by traditional Chinese medical science. Moreover, the invention also discloses a preparation method of the traditional Chinese medicinal composition for curing the coronary disease and heart failure. By adopting a microwave auxiliary extraction process, the preparation method guarantees the medicinal effects of the product and improves the yield of a target component at the same time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating coronary heart disease and heart failure. In addition, the present invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] So far, there have been various schemes for angiogenesis therapy for ischemic heart disease, and basic research and clinical trials have been carried out. Its representatives are: [0003] ①Intramyocardial revascularization using laser [0004] Transmyocardial laser revascularization using laser (transmyocardial laser revascularization-rization), as the name suggests, is a means of reconstructing blood flow pathways in the myocardium through laser perforation. Research began in 1980. However, the created pathway was closed shortly after opening, so the long-term blood flow improvement effect is considered to be the effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61P9/10A61P9/04
Inventor 汤秀珍沈平孃唐英杜晨捷虞伟姚譞路钧镧
Owner NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE
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