Method for preparing Chinese medicinal granules for treating cold

A technology of traditional Chinese medicine granules and granules, which is applied in the field of medicine, can solve the problems of large loss of active ingredients of medicinal materials, easy escape of volatile components, and low extraction rate, and achieve the effects of fast drug onset, short extraction time, and high extraction rate

Active Publication Date: 2011-01-26
XIUZHENG PHARMA GROUP HOIDING +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of this invention is to provide a kind of preparation method of the traditional Chinese medicine granule for treating common cold, make the medicine that makes take effect fast, curative effect is high, overcome its extraction rate that existing preparation method exists is low, can't some high boiling point, All low-volatility components are proposed, the volatile components of the drug are easy to escape, and the active components of the medicinal materials are greatly lost.

Method used

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  • Method for preparing Chinese medicinal granules for treating cold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Take 200g of nepeta panicles, 60g of mint, 100g of windproof, 100g of Bupleurum, 60g of perilla leaves, 100g of kudzu root, 60g of bellflower, 80g of bitter almond, 60g of angelica, 200g of kudiding, and 160g of reed rhizome.

[0023] Preparation:

[0024] ①Take 200g of nepeta panicles, 60g of mint, and 60g of perilla leaves, grind them into 30-mesh coarse powder, and use supercritical CO2 to extract the volatile oil, the extraction temperature is 40°C, the extraction pressure is 40Mpa, the extraction time is 30 minutes, and the CO2 flow rate is 20kg / h, the dregs of the medicine are collected in another device for standby;

[0025] ②Take 100g of Bupleurum bupleurum, 100g of Fangfeng, 100g of kudzu root, 60g of bellflower, 80g of bitter almond, 60g of Angelica dahurica, 200g of kudiding, and 160g of reed rhizome, grind them into 30 mesh coarse powder, and add 10 times the weight of water to super High-pressure extraction once, the pressure is 300MPa, and the pressure i...

Embodiment 2

[0028] Take 200g Nepeta panicle, 60g mint, 100g Fangfeng, 100g Bupleurum, 60g perilla leaf, 100g kudzu root, 60g bellflower, 80g bitter almond, 60g Angelica dahurica, 200g Kudiding, and 160g reed rhizome for later use.

[0029] Preparation:

[0030] ①Take 200g of Nepeta panicles, 60g of mint, and 60g of perilla leaves, crush them into 60-mesh coarse powder, and use supercritical CO2 to extract the volatile oil. The extraction temperature is 30°C, the extraction pressure is 15Mpa, the extraction time is 50 minutes, and the CO2 flow rate is 25kg / h, the dregs of the medicine are collected in another device for standby;

[0031] ②Take 100g of Bupleurum bupleurum, 100g of Fangfeng, 100g of kudzu root, 60g of Platycodon grandiflorum, 80g of bitter almond, 60g of Angelica dahurica, 200g of kudiding, and 160g of reed rhizome, grind them into 60 mesh coarse powder, and add 6 times the weight, Ultrahigh-pressure extraction with 8 times the weight of water twice, the pressure is 100MPa...

Embodiment 3

[0034] Take 200g Nepeta panicle, 60g mint, 100g Fangfeng, 100g Bupleurum, 60g perilla leaf, 100g kudzu root, 60g bellflower, 80g bitter almond, 60g Angelica dahurica, 200g Kudiding, and 160g reed rhizome for later use.

[0035] Preparation:

[0036] ①Take 200g of nepeta panicles, 60g of mint, and 60g of perilla leaves, grind them into 40 mesh coarse powder, and use supercritical CO2 to extract the volatile oil, the extraction temperature is 25°C, the extraction pressure is 10Mpa, the extraction time is 100 minutes, and the CO2 flow rate is 48kg / h, the dregs of the medicine are collected in another device for standby;

[0037]②Take 100g of Bupleurum bupleurum, 100g of Fangfeng, 100g of kudzu root, 60g of bellflower, 80g of bitter almond, 60g of Angelica dahurica, 200g of kudiding, and 160g of reed rhizome, grind them into 40 mesh coarse powder, and add 10 times the weight, 8 times the weight, 6 times the weight of water ultra-high pressure extraction 3 times, the pressure is ...

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Abstract

The invention discloses a method for preparing Chinese medicinal granules for treating a cold, which belongs to the field of medicine and overcomes the defects of low extraction rate of the conventional preparation method and high effective ingredient loss of medicaments. The preparation method comprises the following steps of: crushing schizonepeta spike, mint and perilla leaf into coarse powderaccording to a formula of cold heat clearing granules (No.1-644, version 2005), and extracting the medicaments with volatile oil by adopting supercritical CO2 and ultrahigh pressure; crushing bupleurum, parsnip, kudzuvine root, platycodon root, bitter almond kernel, angelica dahurica, bunge's corydalis and reed rhizome into coarse powder, mixing the coarse powder and the rest medicament residue of the extracted medicaments, performing ultrahigh pressure extraction by adding water, filtering the extract, and concentrating the extract with reduced pressure to form clear paste; and adding auxiliary materials into the clear paste to prepare granules, and adding volatile oil into the granules to obtain the Chinese medicinal granules. The method has the advantages of preventing oxidation, dissipation and reaction of thermo-sensitive components, completely keeping the bioactivity of biomass and reducing loss of effective ingredients along with quicker medicament response and stronger function.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of traditional Chinese medicine granules for treating colds. Background technique [0002] Influenza is a clinically common disease and frequently-occurring disease. Its clinical manifestations are fever, headache, sneezing, sore throat, malaise, aches and other symptoms. Some experts calculated an account for its market capacity: about 75% of people in our country suffer from at least one cold every year. That is to say, nearly 1 billion people need to use cold medicine at least once a year. Based on the average dosage of 15 to 20 yuan each time, the medicine for treating colds has a market space of at least 15 billion to 20 billion yuan per year. Ganmao Qingre Granules is a pure Chinese medicine preparation, which is an effective clinical prescription for many years. It is made of 11 traditional Chinese medicines. It has the effect of dispell...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P31/16A61P11/00
Inventor 高文功高陆高红梅李君海朱丽佳付强赵源慧
Owner XIUZHENG PHARMA GROUP HOIDING
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