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Medical colloid dressing and application thereof

A technology of colloid and antibacterial agent, which is applied in the field of medicine and biomaterials, can solve the problems of insufficient antibacterial effect and antibacterial effect, and achieve the effect of promoting wound healing, significant treatment and repair, and inhibiting scar hyperplasia

Active Publication Date: 2013-11-20
青岛童医生海洋生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the antibacterial effect of these water-soluble chitin derivatives is still insufficient, and its antibacterial effect is still insufficient when used in the healing treatment of ulcer infected wounds.

Method used

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  • Medical colloid dressing and application thereof
  • Medical colloid dressing and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] The preparation of medical colloid dressing A: take water-soluble chitin derivative chitosan quaternary ammonium salt 1.5g, antibacterial agent chlorhexidine acetate 0.05g respectively as solute, put the above-mentioned solute in a clean normal saline bottle, pour Add 100ml of physiological saline as a solvent into the bottle, stir to dissolve into a uniform hydrogel, cover the bottle, and sterilize it at 121°C for 20 minutes with moist heat to obtain medical colloid dressing A. The mass concentration containing chitosan quaternary ammonium salt in the medical colloid dressing A is 15g / L, and the mass concentration containing chlorhexidine acetate is 0.5g / L.

Embodiment 2

[0011] Preparation of medical colloid dressing B: Weigh 3.0 g of water-soluble chitin derivative carboxymethyl chitosan sodium salt and 0.75 g of bacteriostatic agent chlorhexidine acetate as solutes, and place the above solutes in a clean normal saline bottle , add solvent Ringer's solution 100ml to the bottle, stir to dissolve into a uniform hydrogel, cover the bottle stopper, and sterilize with damp heat at 121°C for 20min to obtain medical colloid dressing B. The mass concentration containing carboxymethyl chitosan sodium salt in the medical colloid dressing B is 30g / L, and the mass concentration containing chlorhexidine acetate is 7.5g / L.

Embodiment 3

[0013] Preparation of medical colloid dressing C: Weigh 2.0 g of water-soluble chitin derivative carboxymethyl chitin sodium salt, 5 g of water-soluble chitin derivative hydroxypropyl chitosan, and 1.5 g of bacteriostatic agent chlorhexidine acetate. Solute, put the above solute in a clean normal saline bottle, add 100ml of solvent distilled water into the bottle, stir to dissolve into a uniform hydrogel, cover the bottle stopper, and sterilize with damp heat at 121°C for 20 minutes to obtain medical colloid dressing C . The medical colloid dressing C contains 20 g / L of carboxymethyl chitin sodium salt, 50 g / L of hydroxypropyl chitosan, and 15 g / L of chlorhexidine acetate.

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Abstract

The invention relates to a medical colloid dressing and application thereof, in particular to a medical colloid dressing with the effects of easing pain, promoting surface of burns and scalds healing and restraining bacteria and application thereof. The dressing mainly comprises water-soluble chitin and chlorhexidine.

Description

technical field [0001] The invention relates to a medical dressing and its application, in particular to a medical colloidal dressing and its application, and belongs to the field of medicine and biological materials. Background technique [0002] Chitin, chitosan and their derivatives are the amino polysaccharides with the most abundant resources. Many experimental studies at home and abroad have shown that chitin, chitosan and their derivatives have a wide range of physiological activities, good biocompatibility, biodegradable. Water-soluble chitin derivatives are water-soluble amino polysaccharides formed by chemical modification of chitin, such as carboxymethyl chitin sodium salt, carboxymethyl chitosan sodium salt, succinyl chitosan sodium salt, hydroxypropyl chitin Chitosan, hydroxyethyl chitosan, hydroxypropyl chitin, hydroxyethyl chitin, chitosan quaternary ammonium salt, etc. These water-soluble chitosan derivatives have hemostatic and analgesic functions, promote...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/46A61K31/722A61K47/36A61P17/02
Inventor 潘学理
Owner 青岛童医生海洋生物科技股份有限公司
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