Tegafur and gimeracil compound injecta
A technology of tegafur and injection, which is applied in the field of injection, can solve the problems of drug malabsorption, technical difficulties in preparation, and large differences in individual drug absorption, etc., so as to alleviate the weight loss of the small intestine, achieve good therapeutic effect, and reduce gastrointestinal side effects Effect
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Embodiment 1
[0013] Tegafur 10g, Gimexast 2.18g 0.1M Potassium Hydroxide Solution, Sodium Sulfite 1g
[0014] Water for injection to 1000ml, the water for injection is pre-adjusted to pH 10 with 0.1M potassium hydroxide
[0015] Take 800ml of water for injection with adjusted pH, heat it to 40°C, add active ingredients such as tegafur and gimexast, stir to dissolve, add sodium sulfite, add water for injection with adjusted pH to the prescribed amount, filter and sterilize, and pack To 100 ampoules, each bottle contains 100mg tegafur, 21.8mg gimexast.
Embodiment 2
[0017] Tegafur 5g, Gemelast 1.09g, 0.1M Potassium Hydroxide Solution
[0018] Water for injection to 1000ml, the water for injection is pre-adjusted to pH 10 with 0.1M potassium hydroxide
[0019] Take 800ml of water for injection with adjusted pH, heat it to 40°C, add active ingredients such as tegafur and gimexast, stir to dissolve, make up the water for injection with adjusted pH to the prescribed amount, filter and sterilize, and pack into 100 ampoules Each dose contains 50mg of tegafur and 10.9mg of gimelast.
Embodiment 3
[0021] Tegafur 10g, Gemelast 2.18g, 1M Potassium Carbonate Solution
[0022] Water for injection to 1000ml, the water for injection is pre-adjusted to pH 10 with 1M potassium carbonate solution
[0023] Take 800ml of water for injection with adjusted pH, heat it to 40°C, add active ingredients such as tegafur and gimexast, stir to dissolve, make up the water for injection with adjusted pH to the prescribed amount, filter and sterilize, and pack into 100 ampoules Each dose contains 100mg tegafur and 21.8mg gimelast.
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