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A technology of drugs and marine plants, which is applied in drug combinations, skeletal diseases, medical formulas, etc., can solve the problems of few bone-forming protein drugs, long treatment time, unsatisfactory effects, etc. low effect
Active Publication Date: 2012-09-05
郭宏昌
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[0002] At present, the best drug to promote fracture healing is bone morphogenetic protein, but there are very few substances for making bone morphogenetic protein drugs, so the price is expensive
Traditional Chinese and Western medicines are used for the treatment and prevention of nonunion, femoral head necrosis, and osteoporosis. The treatment time is long and the effect is not satisfactory.
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[0027] The present invention will be further described below in conjunction with embodiment:
[0028] The medicine for treating and preventing fractures of the present invention is prepared from kelp, algae marine plants rich in alginic acid, and acetic acid or acetic anhydride; its preparation method is as follows:
[0029] a. Take kelp and algae marine plants rich in alginic acid, dry and crush them into powder, soak the powder in acetic acid, add acetic acid to submerge the seaweed powder, react at room temperature for 2-3 weeks, and detect the degree of acetylation of the seaweed, Confirm that the end point of the reaction is reached (take 50 g of the reaction product, add 10 ml of acetic anhydride and 0.3 ml of sulfuric acid and mix it, and the reaction can be considered as reaching the end point if there is no more exothermic reaction); after the reaction, pour off the acetic acid liquid and dry at room temperature. Then it is neutralized with sodium hydroxide or other a...
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Abstract
The invention discloses a drug for treating and preventing fracture, which is prepared by the ingredients of kelp, marine alga plant rich in algin and acetic acid or acetic anhydride. The preparation method of the drug is as follows: a, getting kelp and marine alga plant rich in algin, drying and grinding to powder, soaking the powder in acetic acid, wherein, the amount of the acetic acid added is in a standard that the acetic acid immerses the marine alga powder to carry out reaction for 2-3 weeks at normal temperature, pouring out the acetic acid liquid after the reaction is finished, drying under normal temperature, after drying, neutralizing through sodium hydroxide or other alkaline substance, after neutralizing, drying under normal temperature, and getting the substance used for preparing the drug for promoting fracture healing; and b, getting the kelp and the marine alga plant rich in the algin, drying and grinding to powder, soaking the powder in the acetic anhydride, the amount of the acetic anhydride added is in a standard that the acetic anhydride immerses the marine alga powder, then adding sulfuric acid for catalytic reaction, wherein the amount of the sulfuric acid added is 0.3% of the amount of the acetic anhydride, pouring out the acetic acid liquid after the reaction is over, drying under normal temperature, after drying, neutralizing through sodium hydroxide or other alkaline substance, after neutralizing, drying under normal temperature, and finally getting the substance used for preparing the drug for promoting fracture healing.
Description
technical field [0001] The invention belongs to medical clinical medicine, and in particular relates to a medicine suitable for the treatment and prevention of fracture, nonunion, femoral head necrosis and osteoporosis. Background technique [0002] At present, the best drug to promote fracture healing is bone morphogenetic protein, but there are very few substances for making bone morphogenetic protein drugs, so the price is expensive. Traditional Chinese and Western medicines are used for the treatment and prevention of nonunion, femoral head necrosis, and osteoporosis. The treatment time is long and the effect is not satisfactory. Contents of the invention [0003] The object of the present invention is to provide a medicine for treating and preventing fractures with simple preparation method and wide source of raw materials. [0004] The purpose of the present invention can be achieved through the following technical measures: [0005] The medicine for treating and p...
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