Traditional Chinese medicine aerosol for treatment of infantile cough

A pediatric cough and aerosol technology, applied in aerosol delivery, drug combination, pharmaceutical formulation and other directions, can solve the problems of misdiagnosed as upper respiratory tract infection, economic burden of toxic and side effects, airway mucosal hyperresponsiveness, etc. High availability, high drug concentration, fast onset effect

Inactive Publication Date: 2013-07-31
赵广林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main pathological change is the interaction between inflammatory cells, inflammatory mediators, cytokines and airway tissue and cells, resulting in persistent airway inflammatory response and airway mucosal hyperresponsiveness, often misdiagnosed as upper respiratory tract infection, bronchitis, The long-term use of multiple antibiotics has not only caused unnecessary side effects, additional economic burden, but also delayed the progress of the disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0023] (1) Take 200g of Shiwei, 150g of Polygonum cuspidatum, 170g of Citron, 230g of Angelica dahurica, 120g of Scallion, 150g of mulberry leaves, and 170g of white cardamom, add it to 7 times its mass and soak in water for 3 hours, extract under normal pressure reflux for 2 hours, and filter out the solution; Then add the water that accounts for 4 times of its quality and reflux for 2 hours under normal pressure in the medicinal material, and filter the filtrate; combine the filtrate twice and concentrate, the volume of the concentrated medicinal solution is 800ml, and the concentrated solution is reduced to 80% of 3 times the volume (V / V) in ethanol, leave to settle for 24 hours, filter; filtrate reclaims ethanol, and the volume of concentrated medicinal solution is 700ml;

[0024] (2) After adding 80% (V / V) ethanol accounting for 7 times of its mass to the residue of the above medicinal materials and mixing, leave it at room temperature for 24 hours, and filter; the filtra...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine aerosol for treatment of infantile cough. According to traditional Chinese medical science, etiological factors of infantile cough include phlegm-heat accumulation, exterior disorder, interior and exterior inharmony, phlegm stagnation in air ways and failure of lung qi in dispersion. Therefore, traditional Chinese medicines including pyrrosialeaf, polygonum cuspidatum, citron fruit, angelica dahurica, fistular onion stalk, folium mori and amomum cardamomum, which have functions of freeing lung and relieving asthma, clearing lung heat, and eliminating phlegm and relieving a cough, are used for preparing the aerosol in the drug manufacturing room of the people's hospital of Yinan county. According to clinical tests in the people's hospital of Yinan county, the total effective rate reaches 97.3% which is evidently higher than control groups. The traditional Chinese medicine aerosol is externally and locally applied, high in medicineutilization rate, low in toxic and adverse effect, convenient in use, quick in effectiveness and worthy of clinical popularization and application.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine aerosol for treating cough in children. Background technique [0002] Pediatric cough is the most common respiratory disease that seriously affects children's physical and mental health. It is one of the common chronic coughs in pediatric outpatient clinics. In recent years, the prevalence and mortality of children with asthma have been on the rise. Clinically, the main manifestation is recurrent cough. The main pathological change is the interaction between inflammatory cells, inflammatory mediators, cytokines and airway tissue and cells, resulting in persistent airway inflammatory response and airway mucosal hyperresponsiveness, often misdiagnosed as upper respiratory tract infection, bronchitis, The long-term use of multiple antibiotics has not only caused unnecessary side effects, additional economic burden, but also delayed the con...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/12A61K36/9064A61P11/14
Inventor 赵广林
Owner 赵广林
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