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Traditional Chinese medicine composite for treating thyroid associated ophthalmopathy and preparation method thereof

A composition and thyroid technology, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as no control group, achieve less adverse reactions, reduce the incidence of adverse symptoms, and improve TCM syndrome effect of weather

Inactive Publication Date: 2013-07-03
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of the clinical studies on the treatment of thyroid-related ophthalmopathy with traditional Chinese medicine are case reports, and most reports do not have a control group

Method used

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  • Traditional Chinese medicine composite for treating thyroid associated ophthalmopathy and preparation method thereof
  • Traditional Chinese medicine composite for treating thyroid associated ophthalmopathy and preparation method thereof
  • Traditional Chinese medicine composite for treating thyroid associated ophthalmopathy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of Chinese medicine solution of the present invention. Take 60 grams of turmeric, 45 grams of red peony root, 30 grams of salvia miltiorrhiza, 120 grams of coix seed, 20 grams of fritillary fritillary, 15 grams of silkworm, and 80 grams of litchi core. ~ 1.5 hours, filter, and the filtrate is set aside; add 6 times the above filter residue, that is, 2220 grams of water, decoct for 1 ~ 1.5 hours, filter, and the filtrate is set aside; combine the above two filtrates to obtain a Chinese medicine composition solution.

Embodiment 2

[0029]Preparation of traditional Chinese medicine extract of the present invention. Take 30 grams of turmeric, 60 grams of red peony root, 80 grams of salvia miltiorrhiza, 60 grams of coix seed, 60 grams of fritillary fritillary, 10 grams of silkworm, and 30 grams of litchi core. ~ 1.5 hours, filter, and the filtrate is set aside; add 6 times the above filter residue, that is, decoct 1980 grams of water for 1 ~ 1.5 hours, filter, and the filtrate is set aside; combine the above two filtrates to obtain a Chinese medicine composition solution; The filtrates were combined and concentrated to a relative density of 1:1 to obtain an extract.

Embodiment 3

[0031] The preparation of the traditional Chinese medicine sugar-free granule of the present invention. Take 400 grams of turmeric, 350 grams of red peony root, 300 grams of salvia miltiorrhiza, 1000 grams of coix seed, 200 grams of fritillary fritillary, 100 grams of silkworm, and 600 grams of litchi core. ~ 1.5 hours, filter, and the filtrate is set aside; add 6 times the above filter residue, that is, decoct 17700 grams of water for 1 ~ 1.5 hours, filter, and the filtrate is set aside; combine the above two filtrates to obtain a Chinese medicine composition solution; The filtrates are combined and concentrated to a relative density of 1:1 to obtain an extract; the above extract is placed in a spray dryer and sprayed dry to obtain sugar-free granules.

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Abstract

The invention discloses a traditional Chinese medicine composite for treating thyroid associated ophthalmopathy and a preparation method of the traditional Chinese medicine composite. The traditional Chinese medicine composite is prepared from the following traditional Chinese medicines in parts by weight: 30-60 parts of radix curcumae, 30-60 parts of root of common peony, 30-80 parts of salviae miltiorrhizae, 60-120 parts of semen coicis, 20-60 parts of thunberg fritillary bulb, 10-30 parts of stiff silkworm and 30-80 parts of semen litchi. The invention designs a multi-time extraction technical route by taking water as a solvent. The traditional Chinese medicine composite disclosed by the invention can effectively lower the exophthalmos degree of the disease eye of the thyroid associated ophthalmopathy, and the total effective rate is 86.9%; the total effective rate of the main eye symptom and the sign integral curative effect of the disease eye of the thyroid associated ophthalmopathy is 91.8%; the total effective rate of the Chinese medicine syndrome integral curative effect of the thyroid associated ophthalmopathy patient is 90.3%; the lesion activity grade of the disease eyeof the thyroid associated ophthalmopathy can be effectively improved; and the thyroid function of the patient can be improved. The traditional Chinese medicine composite has high safety. The invention also discloses a preparation method for the traditional Chinese medicine composite granule.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating thyroid associated ophthalmopathy (TAO) and a preparation method thereof. Background technique [0002] Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune disease associated with abnormal thyroid function, and is the most common cause of exophthalmos in one or both eyes in adults. Also known as thyroid-associated immune orbitopathy, infiltrating exophthalmos, Graves ophthalmopathy, etc. Due to factors such as social and economic development, accelerated pace of life, increased work pressure, and increased iodine intake, the number of patients with abnormal thyroid function has increased significantly, and the incidence of related TAO has also increased year by year. According to statistics, the prevalence of TAO has reached 1%, and TAO has become the most com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K36/71A61K36/537A61K36/8994A61K36/8966A61K35/64A61K36/77A61P27/02A61P5/14
Inventor 谢学军邓亚平
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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