Drug for treating chronic arrhythmia

A technology of arrhythmia and slowness, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as prone to discomfort symptoms, and achieve the effect of improving the average ventricular rate

Inactive Publication Date: 2018-09-28
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the above-mentioned medicines are mainly warming and tonifying dryness medicines, for a considerable number of patients with Yin-deficiency syndrome, it is easy to produce discomfort symptoms.

Method used

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  • Drug for treating chronic arrhythmia
  • Drug for treating chronic arrhythmia
  • Drug for treating chronic arrhythmia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0117] Embodiment 1 (granule)

[0118] 1. Prescription: Epimedium 2500g, Cinnamon 1000g, Astragalus 2000g, Schisandra 1500g, Rhodiola 1000g, Panax notoginseng 1000g, Chenpi 1000g.

[0119] 2. Preparation method:

[0120] (1) Take Panax notoginseng, add 8 times the amount of 70% ethanol and extract under heat reflux for 3 times, each time for 1.5 hours, collect and combine the ethanol extract, filter, and the filtrate is decompressed to recover ethanol and concentrate to 60 °C with a relative density of 1.10 Extract, spare;

[0121] (2) Take the other raw materials except Panax notoginseng, add water and decoct 3 times, boil for 30 minutes after the first boiling, fry for 1 hour after the second boiling, and fry for 1.5 hours after the third boiling, combine Decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.25 at 80°C, set aside;

[0122] (3) Place the extracts prepared in steps (1) and (2) together in an oven, ba...

Embodiment 2

[0124] Embodiment 2 (granule)

[0125] 1. Prescription: Epimedium 2600g, Cinnamon 900g, Astragalus 2200g, Schisandra 1400g, Rhodiola 1100g, Panax notoginseng 900g, Chenpi 900g.

[0126] 2. Preparation method:

[0127] Prepare granules according to the method described in Example 1.

Embodiment 3

[0128] Embodiment 3 (granule)

[0129] 1. Prescription: Epimedium 2500g, Cinnamon 900g, Astragalus 2200g, Schisandra 1700g, Rhodiola 900g, Sanqi 900g, Chenpi 900g.

[0130] 2. Preparation method:

[0131] Prepare granules according to the method described in Example 1.

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PUM

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Abstract

The invention relates to a drug for treating chronic arrhythmia. The drug is prepared from active ingredients and a pharmaceutically acceptable excipient, wherein the active ingredients include, by weight, 23-28% of herba epimedii, 9-11% of cortex cinnamomi, 18-22% of radix astragali, 14-17% of fructus schisandrae chinensis, 9-11% of rhizome of Rhodiola sachalinensis, 9-11% of radix notoginseng and 9-11% of pericarpium citri reticulatae. The drug can be prepared into common granules or capsules or tablets by using conventional methods. Through clinical verification, the drug for treating the chronic arrhythmia is remarkable in therapeutic effect, causes no adverse reactions and has no toxic and side effects.

Description

technical field [0001] The present invention relates to medical preparations, in particular to traditional Chinese medicine preparations containing undetermined structures from plants for treating bradyarrhythmia Background technique [0002] Bradyarrhythmia is a common clinical arrhythmia. Arrhythmia can be caused by various diseases such as coronary heart disease, hypertensive heart disease, heart failure, viral myocarditis, hypothyroidism, and autonomic dysfunction. Clinically, it often manifests as palpitations and restlessness in the heart, conscious heart beating, panic, involuntary, paroxysmal or persistent, accompanied by chest tightness, shortness of breath, or even chest pain, shortness of breath, cold sweating of extremities, and syncope. It belongs to the category of "heart palpitations" in traditional Chinese medicine. With the fast pace of life, high work pressure, strong psychological stress, such as more alcohol and tobacco addiction, less physical activity...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/752A61P9/06
CPCA61K36/296A61K36/258A61K36/41A61K36/481A61K36/54A61K36/57A61K36/752A61K36/79A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P9/06A61K2300/00
Inventor 贾钰华徐煜凌周凤华孙晓敏刘晓瑜余林中
Owner SOUTHERN MEDICAL UNIVERSITY
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