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A kind of external preparation for reducing swelling and relieving pain and preparation method thereof

A topical preparation, a technology for reducing swelling and pain relief, applied in the directions of non-central analgesics, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problems of unsatisfactory treatment effect of osteoarthritis and few reliable drugs, etc. , to achieve the effect of no toxic side effects, fast onset time and safe medication

Active Publication Date: 2017-11-10
王和鸣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment effect of osteoarthritis has been unsatisfactory for a long time, and there are not many reliable drugs that can improve the function
[0003] After checking the Chinese Pharmacopoeia and the drug standards issued by the Ministry (Bureau), although Zhongjiefeng and Jiujiecha are widely used as raw materials for oral and injection preparations, the unilateral preparation has the effects of clearing away heat and detoxification, reducing inflammation and pain, and relaxing tendons and activating collaterals. The market volume Great, but no topical medicines

Method used

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  • A kind of external preparation for reducing swelling and relieving pain and preparation method thereof
  • A kind of external preparation for reducing swelling and relieving pain and preparation method thereof
  • A kind of external preparation for reducing swelling and relieving pain and preparation method thereof

Examples

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preparation example Construction

[0026] A preparation method of an external preparation for reducing swelling and relieving pain, comprising the following steps:

[0027] 1) By weight, take the following raw materials:

[0028]

[0029] 2) Prepare the extracts of S. chinensis, safflower, angelica, clematis, shenjincao, and Speranza:

[0030] Take 6 kinds of raw materials of sarcophagus, safflower, angelica, clematis, shenjincao and skunkgrass, add water to decoct twice, add water 5-6 times the total weight of the above 6 kinds of raw materials each time, and decoct for 0.8 -1 hour, filter and combine the filtrate;

[0031] Concentrate the filtrate under reduced pressure to obtain a concentrated solution, the volume of the concentrated solution is 1 / 3-1 / 4 of the volume of the filtrate, then centrifuge the concentrated solution at a speed of 3000-4000r / min for 10-15min, and take the supernatant;

[0032] Pass the above supernatant through a resin column equipped with HPD-400 macroporous adsorption resin, t...

Embodiment 1

[0039] A preparation method of an external preparation for reducing swelling and relieving pain, comprising the following steps:

[0040] 1) By weight, take the following raw materials:

[0041]

[0042] 2) Prepare the extracts of S. chinensis, safflower, angelica, clematis, shenjincao, and Speranza:

[0043] Take 6 kinds of raw materials of sarcophagus, safflower, angelica, clematis, shenjincao, and sarcophagus, add water to decoct twice, add water 6 times the total weight of the above 6 kinds of raw materials each time, decoct for 1 hour, Filter and combine the filtrates;

[0044] Concentrating the filtrate under reduced pressure to obtain a concentrated solution, the volume of the concentrated solution is 1 / 4 of the volume of the filtrate, and then the concentrated solution is centrifuged at a speed of 4000r / min for 15min, and the supernatant is taken;

[0045] The above supernatant is passed through a resin column equipped with HPD-400 macroporous adsorption resin, th...

Embodiment 2

[0072] A preparation method of an external preparation for reducing swelling and relieving pain, comprising the following steps:

[0073] 1) By weight, take the following raw materials:

[0074]

[0075] 2) Prepare the extracts of S. chinensis, safflower, angelica, clematis, shenjincao, and Speranza:

[0076] Take 6 kinds of raw materials of sarcophagus, safflower, angelica, clematis, shenjincao, and sarcophagus, add water to decoct twice, add water 6 times the total weight of the above 6 kinds of raw materials each time, decoct for 1 hour, Filter and combine the filtrates;

[0077] Concentrate the filtrate under reduced pressure to obtain a concentrated solution, the volume of the concentrated solution is 1 / 4 of the volume of the filtrate, then centrifuge the concentrated solution at a speed of 3000r / min for 10min, and take the supernatant;

[0078] The above supernatant is passed through a resin column equipped with HPD-400 macroporous adsorption resin, the volume ratio...

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Abstract

The invention discloses an external preparation for reducing swelling and relieving pain and a preparation method thereof. The external preparation comprises raw materials in the following ratios by weight: 15-20 parts of sarcophagus, 9-15 parts of safflower, 9-15 parts of angelica, 9-15 parts of Clematis clematis, 9-15 parts of Streptococcus sinensis, 9-15 parts of Sperantospermia, 30-40 parts of camphor oil, 5-7 parts of borneol, 5-7 parts of menthol; the preparation of the external preparation The method is as follows: prepare the oil phase from camphor oil, stearic acid, glyceride, etc., prepare the water phase from triethanolamine, OP emulsifier, etc., then add the water phase to the oil phase, stir while adding, add an appropriate amount of essence below 40 ° C , and the extract prepared by sargassum, etc., borneol-menthol ethanol solution, mixed slowly by fusion method, cooled, and obtained. The external preparation of the invention has a fast onset time, can effectively improve syndromes of traditional Chinese medicine, is safe to use, has no toxic and side effects, and is a safe and effective medicine for treating knee joint osteoarthritis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an external preparation for reducing swelling and relieving pain and a preparation method thereof. Background technique [0002] Osteoarthritis (OA) is a chronic inflammatory disease of the degenerative joint cartilage. The etiology of osteoarthritis is complex and related to many factors such as age, gender, genetics, obesity, etc., and its true pathogenesis is still not very clear. The goals of current osteoarthritis treatment are to relieve joint pain, improve function, and rebuild damaged cartilage and bone structures as much as possible. However, for a long time, the treatment effect of osteoarthritis is not ideal, and there are not many reliable drugs that can improve the function. [0003] After checking the Chinese Pharmacopoeia and the drug standards issued by the Ministry (Bureau), although Zhongjiefeng and Jiujiecha are widely used as...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/716A61P19/02A61P29/00
Inventor 王和鸣蔡树河陈水金霍康富
Owner 王和鸣
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