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Right supporting and toxin eliminating oral liquid and preparation method of oral liquid

A technology for strengthening the body and detoxifying, oral liquid, applied in the direction of antiviral agents, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of low bioavailability, inconvenient use, etc. The effect of reducing production costs

Inactive Publication Date: 2012-10-10
HENAN SOAR VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since Fuzhengjiedu powder is a traditional Chinese medicine powder, it needs to be taken with ingredients, so it has the disadvantages of inconvenient use and relatively low bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A Fuzheng Jiedu oral liquid is prepared from the following raw materials in weight percent: 40% Radix Radix Radix, 40% Radix Astragali and 20% Epimedium. The preparation method of the Fuzheng Jiedu Oral Liquid is as follows: take the crude drug in proportion and grind it into a coarse powder, add water 10 times the weight of the crude drug, adjust the pH to 2.0 with hydrochloric acid, reflux extraction for 0.5h, and then use bicarbonate The sodium solution was adjusted to a pH of 5.5, refluxed for extraction for 1 hour, the extract was centrifuged in a high-speed centrifuge (15000r / min), the supernatant was concentrated under reduced pressure to the same weight as the raw drug, and then separated by a membrane to obtain a clarified liquid. Potassium sorbate of 0.1% by weight of the clarified liquid is added to the clarified liquid, then diluted with water to the same weight as the crude drug, and canned to obtain the product.

Embodiment 2

[0018] A Fuzheng Jiedu oral liquid is prepared from the following raw materials in weight percent: 40% Radix Radix Radix, 40% Radix Astragali and 20% Epimedium. The preparation method of the Fuzheng Jiedu Oral Liquid is as follows: take the crude drug in proportion and pulverize it into powder, add water 12 times the weight of the crude drug, adjust the pH to 3.0 with hydrochloric acid, reflux extraction for 1 hour, and then use sodium bicarbonate solution Adjust the pH to 6.5, reflux and extract for 0.5h, the extract is centrifuged in a high-speed centrifuge (15000r / min), the supernatant is concentrated under reduced pressure to twice the weight of the raw material drug, and then separated by a membrane to obtain a clear liquid. Add 0.2% potassium sorbate by weight of the clarified liquid into the clarified liquid, then add water to dilute to 2 times the weight of the crude drug, and pack it in a can to obtain the product.

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Abstract

The invention belongs to the technical field of medicine for animals, and particularly relates to right supporting and toxin eliminating oral liquid, which is prepared from the following raw material medicine in percentage by weight: 40 percent of isatis root, 40 percent of astragalus and 20 percent of epimedium herb. A preparation method of the oral liquid comprises the following steps that the raw material medicine is proportionally taken and is crushed into coarse powder, water accounting for 10 to 12 times of the weight of the raw material medicine is added, in addition, the pH is regulated to 2.0 to 3.0 by hydrochloric acid, the reflux extraction is carried out for 0.5 to 1 hour, next, the pH is regulated to 5.5 to 6.5 by sodium bicarbonate, the reflux extraction is carried out for 0.5 to 1 hour, the extraction liquid is concentrated to 1 to 2 times of the raw material medicine through pressure reduction after being filtered, then, clear liquid is obtained after the membrane separation, preservatives are added, the solution is diluted by adding water, and the oral liquid is obtained after the filling. The oral liquid has the advantages that the recipe is reasonable, the absorption rate is high, the addition can be realized through drinking water, and the use is convenient.

Description

technical field [0001] The invention belongs to the technical field of veterinary drugs, and in particular relates to a Fuzhengjiedu oral liquid and a preparation method thereof. Background technique [0002] Fuzheng Jiedu Powder is composed of Radix Radix Isatidis, Radix Astragali and Epimedium Herba. It is recorded in the 2010 edition of "Chinese Veterinary Pharmacopoeia" that Fuzheng Jiedu Powder is mainly used to treat chicken infectious bursal disease. However, because Fuzhengjiedu powder is a traditional Chinese medicine powder, it needs to be taken with mixing ingredients, so it has the disadvantages of inconvenient use and relatively low bioavailability. Contents of the invention [0003] The object of the present invention is to overcome the disadvantages of the prior art, and provide a Fuzhengjiedu oral liquid and a preparation method thereof. The oral liquid is added through drinking water, and is easy to use and has a high absorption rate. [0004] To achieve ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/08A61P31/14
Inventor 刘升贺培益陈圆圆柴保国
Owner HENAN SOAR VETERINARY PHARMA
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