Labdane diterpenoid compounds, arborvitae seed extract, preparation method thereof and application thereof

A kind of technology of diterpenoids and compounds, applied in the field of helichanoid diterpenoids
CN102746259AActive Publication Date: 2012-10-24SUN YAT SEN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUN YAT SEN UNIV
Publication Date
2012-10-24

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Abstract

The invention provides a plurality of labdane diterpenoid compounds and derivatives thereof, which can be used for preparing pharmaceutical composition for preventing or treating neurodegenerative diseases. The invention also provides an arborvitae seed extract, the arborvitae seed extract contains one or more labdane diterpenoid compounds and the derivatives, and can be used for preparing pharmaceutical composition for preventing or treating neurodegenerative diseases.
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Description

technical field

[0001] The present invention relates to a helianthene-type diterpenoid compound, Semen boitae extract, a preparation method and application thereof. Background technique

[0002] Neurodegenerative diseases (Neuro degenerative diseases, NDD) are a class of chronic, progressive neurological diseases, mainly including Alzheimer's disease (Alzheimer's disease, AD), Parkinson's disease (Pakinson's disease, PD), Huntington's disease (Huntington's disease) , HD), amyotrophic lateral sclerosis (Amyotuophic laterals clerosis, ALS) and so on. These diseases have complex pathophysiological processes, with different lesion sites and etiologies, but neurodegeneration is their common denominator. Patients with neurodegenerative diseases often have symptoms such as memory loss, cognitive difficulties, dementia, movement balance disorders, and loss of motor ability. The quality of life of patients is seriously reduced. economic and psychological stress. As the global popu...

Claims

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