Biological membrane which promotes healing and preparation method thereof

Abstract

The invention discloses a biological membrane which promotes healing and a preparation method thereof. The biological membrane which promotes healing is prepared by mixing chitosan derivative solution and sesame oil for ionic crosslink and drying the mixture to form membrane. The membrane has a certain flexibility and strength and integral gel can be formed after the membrane absorbs exudates. Adhesion with wound surface can be avoided, thus medicine changing is convenient and no secondary injury is caused. In addition, the membrane has the advantages of moist keeping, antibacterial action, scars reducing and the like. The membrane has obvious curative effect of promoting wound to heal and is applicable to curing surgical wound, bruise, burn, donor site, bedsore, diabetic ulcer and other wound surfaces which are difficult to heal.

Description

technical field [0001] The invention relates to a biofilm for promoting healing, in particular to a biofilm for promoting wound healing prepared by taking chitosan derivatives and sesame oil as main raw materials, and belongs to the field of biomedical materials. Background technique [0002] Trauma is the damage of normal skin (tissue) caused by external injury factors such as surgery, external force, heat, electric current, chemical substances, low temperature, and internal factors such as local blood supply disturbance. Common traumas include surgical incisions, abrasions, burns, donor sites, decubitus ulcers, vascular ulcers of lower extremities, diabetic ulcers, and other difficult-to-heal wounds. The formation and existence of trauma will have a major impact on the local and even whole body functions of the body. In order to accelerate the healing of the wound and reduce the infection of the wound surface, dressings are generally used to cover and protect the wound. ...

AI Technical Summary

Problems solved by technology

However, gel preparations of chitosan or its derivatives have the disadvantages of absorbing less wound exudate and difficulty in changing dressings.

However, pure chitosan or its derivative film, sponge or non-woven fabric preparations are limited in use due to poor mechanical properties, melting when encountering liquid, which is not conducive to dressing changes.

Chitosan or its derivative preparations currently under research or on the market are mostly cross-linked products with chemical cross-linking agents, and there is a potential risk of cross-linking agents harming the body

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